StartupBlink Blog


This report depicts the state of the healthtech startup industry in 2022. Providing an in-depth look into the top 30 cities for healthtech as well as the top unicorns, exits, and pantheons, this report details the findings of the Global Startup Ecosystem Index.

Healthtech Industry at a Glance: top insights

➡️ In 2022, the second largest industry in the StartupBlink Index is healthtech, with 12.7% of our sampled startups. On the Startupblink Ecosystem Map there are10 sub-industries for healthtech:  Assisted Living (0.6%), Biotechnology (33.5%), Cannabis (1.4%), Fitness (7%), Health Care (40.9%), Life Sciences (4.7%), Medtech (5.9%), Pharmaceuticals (2.6%) and Health– other (3.5%). 

➡️ The Unicorn count in our sample database for this industry is 73, which represents 6.46% of the total sampled startups. The top location for unicorn startups in healthtech is the United States (53), followed by China (8), India (3), and Finland (2). 

➡️ The number of exits from healthtech represents 13.46% of the total exits in our sample database. The top location for exits is the United States (49), followed by Canada (3), Germany (3), the United Kingdom (2), and  Belgium (2).

➡️ The United States dominates the top 30 destinations for healthtech Startups boasting 17 startup ecosystems that overperform in this industry. The top seven cities are San Francisco Bay, Boston, New York, San Diego, Los Angeles, Denver, and Seattle.

Ranking the top 30 Cities for Healthtech

Healthtech is the second largest industry, as it counts for 12.7% of startup activity. The top 7 cities that host the highest number of startups are; San Francisco Bay, Boston, New York, San Diego, Los Angeles, Denver, and Seattle, respectively. A country comparison shows that The US leads the healthtech industry, followed by China and the United Kingdom. Hence, China overperforms in healthtech in spite of its global ranking. 

With no surprise, San Francisco preserves its position as the leader of the healthtech industry as well.  However, Denver and San Diego are the cities that grab attention, as they are positioned in the top seven, despite their lower position in the global ranking. This year, Boston Area (ranked 2nd)  and New York (ranked 3rd), shrunk the gap with San Francisco to 36% and 58% from last year’s gap of 136% and 189% in 2021. The US cities: Lexington, Louisville, and Nashville have a striking position, showing a 599,99%, 308,3%, and 335,3% increase compared to their global ranking. 

In the healthtech rankings, US cities are catching up with London. Yet, in comparison to last year, London succeeded to increase their position by two spots. It is also important to note that Cambridge and Oxford are ranking a few spots below their 2021 rankings.

Oulu (ranked 30th) is a significant overperformer that shows the most remarkable change of 549,99% compared to its global ranking. Basel and Oxford are ranking better than their global rankings, showing a %239,3 and 268,9% increase, respectively.

Overall, Chinese cities are underperforming in their healthtech rankings, with the exception of Hangzhou, gaining 11 places and positioned at the 19th spot. Yet, its contenders, Beijing (ranked 14th) and Shanghai (ranked 12th) are still ahead. In comparison to the 2021 rankings, Beijing (ranked 14th) and Shenzhen (ranked 31st) showed a fall of 70,9% and 57,1%, respectively.

Healthtech Unicorns in 2022

Unicorns are startups that reach a valuation of one billion dollars or above. Below are the highest-ranked healthtech unicorns from the  StartupBlink database. 

  1. Omada Health

San Francisco, United States

  1. Benchling

San Francisco, United States

  1. Reify Health

San Francisco, United States

  1. Medable

Palo Alto San Francisco, United States

  1. Athletic Greens

New York , United States

  1. Oxford Nanopore Technologies

Oxford, United Kingdom

  1. Proteus Digital Health

Redwood City, United States

  1. Alto Pharmacy

San Francisco, United States

  1. Carbon Health

San Francisco, United States

  1. DispatchHealth

Denver, United States

Healthtech Pantheon Members in 2022

Pantheon member is a category coined by StartupBlink which includes companies or organizations that are no longer a startup or a unicorn but still have a substantial impact on their startup ecosystem and its brand. These Pantheons are categorized into three tiers depending on their impact and quality. Below are the pantheon members making a notable impact in the healthtech industry: 

  1. AstraZeneca

Cambridge, United Kingdom

  1. Novartis

Basel, Switzerland

  1. Pfizer

New York, United States

  1. Moderna

Cambridge, United States

  1. BionTech

Mainz, Germany

Healthtech Exits in 2022

Exit for a startup occurs when the founder sells the company’s ownership to an investor or another company. It is a strategy for many startups that have been decided on since their establishment. Here are the top exits in 2022 according to the StartupBlink database:

  1. Pillpack

Boston, United States

  1. CureVac

Tubingen, Germany

  1. Butterfly Network

Guilford, United States

  1. SmileDirectClub

Nashville, United States

  1. ABILITY Network

Minneapolis, United States

  1. eviCore Healthcare

Bluffton, United States

  1. Everlywell

Austin, United States

  1. Doctor On Demand

San Francisco, United States

  1. Sunrise

Brussels, United States

  1. ATAI Life Sciences

Munich, Germany

Notable Healthtech Startups

  1. Halodoc

Jakarta, Indonesia

Halodoc is a health-tech platform that connects patients with doctors, insurance, labs, and pharmacies in one simple mobile application.

  1. Evidation

San Mateo, United States

Evidation measures health in everyday life and enables anyone to participate in ground-breaking research and health programs.

  1. Anagin

Indianapolis, United States

Anagin is developing first-in-class therapies for treating neuropsychiatric diseases.

  1. MyFitnessPal

San Francisco, United States

MyFitnessPal is a free, comprehensive nutrition and fitness system that makes it easy for you to attain your fitness goals and live healthier. 

  1. WebTeb

Amman, Jordan

WebTeb publishes evidence-based medical information and continuously updates it. The company is managed by a professional team that includes doctors.

  1. Athenahealth

Watertown, United States

Athenahealth is a leading provider of cloud-based business and clinical services for physician practices. 

  1. Medtrics Lab

New York, United States

Medtrics is the only Residency Management Platform built from the ground up for ACGME’s Next Accreditation System.

  1. mindbodygreen

New York, United States

Mindbodygreen is an independent media brand dedicated to wellness.

  1. Validic

Durham, United States

Validic is interoperability for mHealth. Their API platform integrates dozens, and eventually hundreds, of consumer health apps, fitness devices, home health devices, and medical devices. 

  1. Altibbi

Dubai, United Arab Emirates

Altibbi is the Largest Digital Health platform in the Arab World, including 1.5M pages of medical content and a 24/7 telehealth service.


To ensure that the rankings are as accurate as possible, we have based our algorithm on objective, quantifiable data that can be comparatively measured across regions, countries, and cities. We refrained from using subjective tools such as surveys and interviews, and instead utilized data that was either accumulated directly from the StartupBlink map or has arrived from integration with a reliable global data partner. We allow as few assumptions as possible regarding cause and effect and focus on one thing: measuring results. We avoid relying on any theoretical models assuming the causes of success for startup ecosystems. 

Every year our algorithm is more accurate, and it should be noted that the momentum change of each ecosystem is not only influenced by its achievements over the last year, but also by these algorithm improvements. We have been sampling startup ecosystem data on the curated and interactive StartupBlink Global Map, which enables us to test and perfect our algorithm based on vast sets of data. We estimate that the core map dataset has a representative sample covering 10-15% of total relevant entities in global startup ecosystems. In addition, hundreds of thousands of entities and data integrations are taken into account via our global data partners. Each location’s final score is based on the exact same algorithm. However, we are aware that our sample size fluctuates depending on location and data sourcing. Our only intervention in the score is discounting locations where we determined that the sample size of the entities is higher than average. In order to solve issues with lower than average sample size, we have partnered with approximately 100 Ecosystem Partners, most of which are Government agencies, many of them in locations where our data is limited. We offer all governments administrative access to curate the dataset of their ecosystems, at no cost, granting them complimentary access. On our rankings with Unicorns and Exits, we take into account the valuation of each startup and add some special filters to exclude government entities and corporate spin-offs.

The Methodology used in the 11 industry rankings, including Software and Data, is identical to the algorithm of the global rankings while taking into account the startup database of each industry. However, the fintech Industry rankings are built on an official Fintech Ecosystem Portal: Findexable’s Global Fintech Map, which includes deeper algorithm changes customized according to the specific characteristics of the fintech industry.

Our Data Partners: