18 Top startups in Roanoke for January 2025

We rank Slync.io, Floafers and KlariVis in Roanoke along with 15 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Roanoke ranks #605 globally and #165 in United States.

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Best Startups in Roanoke for 2025

SB Score:367

Slync.io offers process automation for enterprise supply chains and the global logistics industry, streamlining operations and increasing efficiency.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:365

Floafers crafts stylish EVA foam shoes for men and women. Lightweight and comfortable, their footwear is ideal for everyday wear. Join the Floafers movement for fashionable, durable shoes that are perfect for any occasion.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (United States)

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SB Score:355

KlariVis is a cutting-edge data analytics platform that provides powerful insights. With its proprietary software, users can easily analyze data to make informed decisions.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:274

PogoTec specializes in developing the world's smallest and lightest camera that seamlessly attaches to nearly all types of glasses. This innovative device empowers users to capture high-quality photos and videos effortlessly, enhancing their daily experiences without compromising style or comfort.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:248

Generated Photos uses advanced technology to create lifelike human faces and bodies that are completely virtual. Their generative adversarial networks (GANs) generate unique and realistic images of people that do not actually exist, providing a valuable resource for a variety of industries.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:214

Coeurative pioneers biotechnology solutions for diseases caused by cellular hypoxia, delivering innovative curative treatments. Their focus is on developing strategies to combat the effects of low oxygen levels in the body.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:188

Acomhal Research, a biotech startup founded in 2017, develops innovative cancer treatments. Co-founded by Dr. Samy Lamouille and Dr. Robert Gourdie at Virginia Tech Carilion, the company focuses on targeting cancer cells with novel therapies.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:187

Nursesbnb is an innovative mid-term rental platform that utilizes proprietary technology to address the housing shortage for traveling healthcare professionals. By connecting them to safe and budget-friendly accommodations, it offers peace of mind and supports the essential workforce in the healthcare industry.

Industry:
Software & Data
Subindustry:
SaaS

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Regional Rank (North America)

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SB Score:187

Chorda Pharma, established by Rick Carliss in 2018 in Roanoke, Virginia, focuses on delivering long-term pain relief solutions for conditions such as arthritis, diabetic neuropathy, and sports injuries. Their innovative treatments aim to enhance the quality of life for those suffering from chronic pain.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:146

Art Money offers innovative financial services that empower art enthusiasts to purchase artwork while supporting artists and galleries. With seamless online payment solutions and secure transaction verification, Art Money enhances the art-buying experience across galleries, auction houses, and digital platforms, fostering growth in the creative economy.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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GEM Equipment & Manufacturing offers a wide range of manufacturing services including laser cutting, metal forming, machining, welding, assembly, and shipping. They specialize in creating carts, returnable packaging, platforms, and contract manufacturing solutions for businesses.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

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Regional Rank (North America)

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Total amount:18

Top 9 Software & Data Startups in Roanoke for 2025

The top three Software & Data startups in Roanoke have raised more than USD 114M. Roanoke ranks #379 globally for the Software & Data industry.
SB Score:367

Slync.io offers process automation for enterprise supply chains and the global logistics industry, streamlining operations and increasing efficiency.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:355

KlariVis is a cutting-edge data analytics platform that provides powerful insights. With its proprietary software, users can easily analyze data to make informed decisions.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:248

Generated Photos uses advanced technology to create lifelike human faces and bodies that are completely virtual. Their generative adversarial networks (GANs) generate unique and realistic images of people that do not actually exist, providing a valuable resource for a variety of industries.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:9

Top 3 Healthtech Startups in Roanoke for 2025

The top three Healthtech startups in Roanoke have raised more than USD 1.62M. Roanoke ranks among the top 10 locations in the world for startups in Healthtech, holding the 2nd position.
SB Score:214

Coeurative pioneers biotechnology solutions for diseases caused by cellular hypoxia, delivering innovative curative treatments. Their focus is on developing strategies to combat the effects of low oxygen levels in the body.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:188

Acomhal Research, a biotech startup founded in 2017, develops innovative cancer treatments. Co-founded by Dr. Samy Lamouille and Dr. Robert Gourdie at Virginia Tech Carilion, the company focuses on targeting cancer cells with novel therapies.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:187

Chorda Pharma, established by Rick Carliss in 2018 in Roanoke, Virginia, focuses on delivering long-term pain relief solutions for conditions such as arthritis, diabetic neuropathy, and sports injuries. Their innovative treatments aim to enhance the quality of life for those suffering from chronic pain.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:3

Top 2 Hardware & IoT Startups in Roanoke for 2025

The top three Hardware & IoT startups in Roanoke have raised more than USD 2.25M. Roanoke ranks among the top 10 locations in the world for startups in Hardware & IoT, holding the 3rd position.
SB Score:274

PogoTec specializes in developing the world's smallest and lightest camera that seamlessly attaches to nearly all types of glasses. This innovative device empowers users to capture high-quality photos and videos effortlessly, enhancing their daily experiences without compromising style or comfort.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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GEM Equipment & Manufacturing offers a wide range of manufacturing services including laser cutting, metal forming, machining, welding, assembly, and shipping. They specialize in creating carts, returnable packaging, platforms, and contract manufacturing solutions for businesses.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:2

Most Funded Startups in Roanoke for 2025

The top three most funded startups in Roanoke have raised total funding of more than USD 117M. Slync.io has 6.44% more funding than KlariVis.
SB Score:367

Slync.io offers process automation for enterprise supply chains and the global logistics industry, streamlining operations and increasing efficiency.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:355

KlariVis is a cutting-edge data analytics platform that provides powerful insights. With its proprietary software, users can easily analyze data to make informed decisions.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:365

Floafers crafts stylish EVA foam shoes for men and women. Lightweight and comfortable, their footwear is ideal for everyday wear. Join the Floafers movement for fashionable, durable shoes that are perfect for any occasion.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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Total amount:18

Top Hiring Startups in Roanoke by Employee Number

The top three hiring startups in Roanoke have an median employee size that is between [11-50]
SB Score:367

Slync.io offers process automation for enterprise supply chains and the global logistics industry, streamlining operations and increasing efficiency.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:365

Floafers crafts stylish EVA foam shoes for men and women. Lightweight and comfortable, their footwear is ideal for everyday wear. Join the Floafers movement for fashionable, durable shoes that are perfect for any occasion.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:355

KlariVis is a cutting-edge data analytics platform that provides powerful insights. With its proprietary software, users can easily analyze data to make informed decisions.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:274

PogoTec specializes in developing the world's smallest and lightest camera that seamlessly attaches to nearly all types of glasses. This innovative device empowers users to capture high-quality photos and videos effortlessly, enhancing their daily experiences without compromising style or comfort.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:18

Explore the Startup Ecosystem of Roanoke

National Rank

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165th

18

Regional Rank

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189th

19

Global Rank

(WorldWide)

605th

84

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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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3rd
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4th
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121.937
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5th
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109.679
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