7833 Top startups in San Francisco for April 2025

We rank Brave, Scribd and Medium in San Francisco along with 7830 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Francisco startup ecosystem ranks #1 globally and #1 in United States.

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Top Unicorn Startups in San Francisco for 2025

171 startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in San Francisco have raised more than USD 1350T.
SB Score:1000

OpenAI, an AI research and product company, enhances digital intelligence for the greater good. Their innovations, like ChatGPT, aim to improve technology for the benefit of humanity.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:917

Stripe is the ultimate platform for managing your online business. It streamlines all your operations, from processing payments to tracking sales, in one easy-to-use interface. Get started today and watch your internet business thrive with Stripe.

Industry:
Fintech
Subindustry:
Payments

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SB Score:908

Discord connects communities with chat, voice, and video features, perfect for gamers and interest groups. Join the fun in real-time conversations and calls on this popular communication platform.

Industry:
Software & Data
Subindustry:
Software

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Total amount:171

Best Startups in San Francisco for 2025

SB Score:796

Brave, the privacy-focused web browser, blocks trackers and ads for a faster, safer browsing experience. Enjoy a cleaner online experience with enhanced security.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:788

Scribd is the unlimited reading subscription that offers access to the best books, audiobooks, news and magazine articles, documents and more. Scribd's e-book subscription service is available on Android and iOS smartphones and tablets, as well as personal computers. Scribd brings together the best books, audiobooks, and journalism to help readers become their best selves. The company offers unlimited access to the best books, audiobooks, articles, documents, and more, all in one app.

Industry:
Social & Leisure
Subindustry:
Entertainment

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SB Score:742

Medium is revolutionizing idea sharing by tapping into collective creativity and emphasizing the importance of design. They believe in democratizing content creation and shaping a better media landscape. Join their elite team focused on deliberate growth and innovation in engineering and design.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:736

Healthline Networks is a provider of health information and technology solutions for publishers, advertisers, employers, healthcare providers, and health plans. Originally founded as YourDoctor.com in 1999, the company relaunched in 2005 as Healthline Networks and is organized into two business units: Healthline Media and Healthline HIT Solutions. Healthline Media, together with its flagship Healthline.com and YourDoctor.com, is one of the top ten health information destination properties according comScore. Healthline Media also manages HealthWEB—a network of health publishers that include Yahoo! Health, Drugs.com, and many others. Healthline Media is the 2nd largest and fastest growing consumer health publisher in the world, reaching 85 million people a month. You can depend on us to provide expert content along with genuine caring. We will support, guide, and inspire you toward the best possible health outcomes for you and your family. Our solid profitability and rapid growth enables us to invest in expanding our reach and offering to have even more impact on many millions more users. We have offices in San Francisco, New York City, UK, Iceland and Taiwan - and are looking for people who share our vision of a stronger, healthier world! If you're interested in careers with us, please feel free to email us at: collaborate@healthline.com

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:735

Narvar is a customer experience platform that helps retailers inspire long-term customer loyalty, at all steps of the post-purchase journey. It helps retailers inspire loyalty beyond reason. As an enterprise-grade customer experience platform serving 500+ retailers like Sephora, Patagonia, Home Depot, Gap, and Bose, Narvar enables seamless post-purchase experiences that retain, engage, and delight customers — from cart to doorstep, and beyond. With effortless order tracking, proactive communications, and seamless returns, Narvar applies machine learning across billions of interactions to simplify the everyday lives of consumers. The company was established in 2012 and is based in San Francisco, California.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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6th

Deel
SB Score:702

Deel is a comprehensive global compliance and payroll solution that empowers businesses to hire talent from anywhere in the world. Its innovative technology streamlines payroll, HR, compliance, and benefits, enabling companies to efficiently manage their international teams and ensure seamless operations across borders.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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7th

JUUL
SB Score:698

JUUL produces and sells electronic nicotine vaporizers. Their sleek devices provide a convenient and discreet way for users to enjoy nicotine without the smoke and odor of traditional cigarettes.

Industry:
Social & Leisure
Subindustry:
Social & Leisure-Other

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SB Score:695

Change.org is the world’s largest social change platform with over 150 million users in 196 countries. Change.org empowers anyone, anywhere, to create the change they want to see. On Change.org, people everywhere are starting campaigns, mobilizing supporters, and working with decision-makers to drive solutions. Change.org is a certified B-corporation, a new class of companies dedicated to positive impact. Investors include Bill Gates, Arianna Huffington, Ev Williams, Richard Branson, Reid Hoffman, and the Omidyar Network, started by eBay founder Pierre Omidyar.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:691

Motive is a remote-first company that serves more than one million drivers and over 100,000 businesses by building technology to improve the safety, productivity, sustainability, and profitability of businesses that power the physical economy. Shoaib Makani and his co-founders Ryan Johns and Obaid Khan founded the company in 2013 to serve the trucking industry, a workforce that is essential to the economy but underserved by technology. For the first time ever safety, operations and finance teams can manage their drivers, vehicles, equipment, and fleet related spend in a single system. Combined with industry leading AI, the Motive platform gives you complete visibility and control, and significantly reduces manual workloads by automating and simplifying tasks. Motive serves more than 120,000 customers – from Fortune 500 enterprises to small businesses – across a wide range of industries, including transportation and logistics, construction, energy, field service, manufacturing, agriculture, food and beverage, retail, and the public sector. Motive is the only fully unified Integrated Operations Platform, combining Driver Safety, Fleet Management, Equipment Monitoring, and Spend Management all in one place. Motive has more than 3,500 employees across 8 global offices.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:684

RealPage offers rental housing industry software and services on-demand. Streamlining operations for property management, maintenance, and resident services, RealPage is the go-to solution for efficient and effective rental property management.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

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11th

Smule
SB Score:674

Smule is a popular social singing app where users can create and share musical performances with a wide selection of songs and duet options. Join the community and showcase your talent with this interactive platform.

Industry:
Software & Data
Subindustry:
Apps

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Total amount:7833

Top 3749 Software & Data Startups in San Francisco for 2025

The top three Software & Data startups in San Francisco have raised more than USD 4.11B. San Francisco startup ecosystem ranks among the top 10 locations in the world for startups in Software & Data, holding the 1st position.
SB Score:796

Brave, the privacy-focused web browser, blocks trackers and ads for a faster, safer browsing experience. Enjoy a cleaner online experience with enhanced security.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:742

Medium is revolutionizing idea sharing by tapping into collective creativity and emphasizing the importance of design. They believe in democratizing content creation and shaping a better media landscape. Join their elite team focused on deliberate growth and innovation in engineering and design.

Industry:
Software & Data
Subindustry:
Apps

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3rd

Deel
SB Score:702

Deel is a comprehensive global compliance and payroll solution that empowers businesses to hire talent from anywhere in the world. Its innovative technology streamlines payroll, HR, compliance, and benefits, enabling companies to efficiently manage their international teams and ensure seamless operations across borders.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Total amount:3749

Top 783 Fintech Startups in San Francisco for 2025

The top three Fintech startups in San Francisco have raised more than USD 3.61B. San Francisco startup ecosystem ranks among the top 10 locations in the world for startups in Fintech, holding the 1st position.
SB Score:663

Mercury offers specialized banking services and accounts tailored for startups. Simplify your financial management with their digital platform designed to meet the unique needs of new businesses.

Industry:
Fintech
Subindustry:
Online Banking

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SB Score:659

Block is a technology company that offers financial services like Square, Cash App, and Spiral, entertainment through TIDAL, and other innovative projects under TBD. Supported by experienced teams in Counsel, Finance, and People, Block provides guidance at the corporate level for success.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:659

Mission Lane provides transparent and equitable credit solutions for all consumers. Their mission is to ensure that everyone has access to clear and fair credit options.

Industry:
Fintech
Subindustry:
Financial Services

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Total amount:783

Top 615 Healthtech Startups in San Francisco for 2025

The top three Healthtech startups in San Francisco have raised more than USD 5.01B. San Francisco startup ecosystem ranks among the top 10 locations in the world for startups in Healthtech, holding the 1st position.
SB Score:736

Healthline Networks is a provider of health information and technology solutions for publishers, advertisers, employers, healthcare providers, and health plans. Originally founded as YourDoctor.com in 1999, the company relaunched in 2005 as Healthline Networks and is organized into two business units: Healthline Media and Healthline HIT Solutions. Healthline Media, together with its flagship Healthline.com and YourDoctor.com, is one of the top ten health information destination properties according comScore. Healthline Media also manages HealthWEB—a network of health publishers that include Yahoo! Health, Drugs.com, and many others. Healthline Media is the 2nd largest and fastest growing consumer health publisher in the world, reaching 85 million people a month. You can depend on us to provide expert content along with genuine caring. We will support, guide, and inspire you toward the best possible health outcomes for you and your family. Our solid profitability and rapid growth enables us to invest in expanding our reach and offering to have even more impact on many millions more users. We have offices in San Francisco, New York City, UK, Iceland and Taiwan - and are looking for people who share our vision of a stronger, healthier world! If you're interested in careers with us, please feel free to email us at: collaborate@healthline.com

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:648

Doximity connects healthcare professionals for secure communication, career networking, and access to medical news and research. Join the platform for opportunities to connect, collaborate, and stay updated in the ever-evolving field of healthcare.

Industry:
Healthtech
Subindustry:
Health Care

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3rd

Eaze
SB Score:633

Eaze offers legal, safe, and convenient cannabis delivery services, promoting accessibility and education. Experience hassle-free access to cannabis products with professional delivery service.

Industry:
Healthtech
Subindustry:
Cannabis

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Total amount:615

Most Funded Startups in San Francisco for 2025

The top three most funded startups in San Francisco have raised total funding of more than USD 47.6B. JUUL has 13.27% more funding than Altos Labs.

1st

JUUL
SB Score:698

JUUL produces and sells electronic nicotine vaporizers. Their sleek devices provide a convenient and discreet way for users to enjoy nicotine without the smoke and odor of traditional cigarettes.

Industry:
Social & Leisure
Subindustry:
Social & Leisure-Other

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SB Score:530

Altos Labs specializes in rejuvenating cells to reverse disease and improve overall health. Their innovative approach focuses on restoring cellular health and resilience, aiming to transform the field of medicine.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:655

Getaround empowers users to instantly rent and drive great cars shared by people in their city. Cars can be rented by the hour, or the day, with a $1M insurance policy and 24/7 roadside assistance included. By using its app, people skip the lines and paperwork at traditional rental car counters, and the hassle of buying and maintaining a car. Powered by Getaround ConnectTM, the patented connected car technology, Getaround creates a fun and safe carsharing experience is without the need to meet the car owner, carry an access card, or coordinate picking up a car key. People share everything from a Prius to a Tesla and earn thousands in extra income each year, offsetting the high cost of car ownership while also making a positive impact on the environment.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Total amount:7833

Top Hiring Startups in San Francisco by Employee Number

The top three hiring startups in San Francisco have an median employee size that is between [10001+]
SB Score:659

Block is a technology company that offers financial services like Square, Cash App, and Spiral, entertainment through TIDAL, and other innovative projects under TBD. Supported by experienced teams in Counsel, Finance, and People, Block provides guidance at the corporate level for success.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:615

Globant is a digital transformation company that empowers organizations to unlock their complete potential through innovative solutions and reinvention.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:511

Taekus is a fintech company that enhances credit card rewards for travelers by offering 10x the value on premium benefits, starting with airline tickets. With Taekus, users can effortlessly maximize their rewards without the hassle of sifting through complicated fine print.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:428

Cloud Software Group empowers modern enterprises to adapt, transform, and overcome challenges in private, public, and managed sectors.

Industry:
Edtech
Subindustry:
Education-Other

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Total amount:7833

Explore the Startup Ecosystem of San Francisco

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
-
1
37.971
00.00
00.00
00.00
9th
0
24th
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2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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