20 Top startups in Harrisburg for April 2025

We rank Pledge It, MacuLogix and Elephant Energy in Harrisburg along with 17 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Harrisburg startup ecosystem ranks #466 globally and #138 in United States.

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Best Startups in Harrisburg for 2025

SB Score:440

Pledge It empowers athletes to raise funds for their team or cause through performance-based fundraising. Athletes can set goals and supporters can pledge donations based on their achievements.

Industry:
Fintech
Subindustry:
Fintech-Other

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SB Score:392

MacuLogix focuses on detecting and tracking age-related macular degeneration. It leverages the science of dark adaptation to help eliminate preventable blindness caused by AMD. Through its AdaptDx® dark adaptometer, MacuLogix enables eye care professionals to detect, monitor, and start treating AMD three years before it can be seen in order to prevent vision loss.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:253

Elephant Energy simplifies the transition to a gas-free home by offering modern, all-electric heating and cooling systems, as well as appliances. Their services include heat pumps, water heaters, and EV charging solutions, making it easy for homeowners to upgrade to energy-efficient technologies.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:211

Hot Tech Industries specializes in creating an efficient thermodynamic heat transfer process. Their focus is on developing sustainable solutions for heat transfer applications.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:170

Culineer is a mobile app that offers a wide range of delicious food recipes. Users can easily access and follow step-by-step instructions to create mouthwatering dishes. Get ready to explore new culinary experiences and impress your friends and family with your cooking skills.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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SB Score:155

FullStac specializes in creating cloud-based SaaS solutions for small businesses, focusing on eCommerce and business management. Our products are designed to streamline operations and improve efficiency.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:149

INTAG offers cutting-edge biological solutions that enhance nutrient recycling, minimize environmental impact, and boost crop yields for farmers. By integrating innovative practices, INTAG empowers agricultural sustainability and improves the efficiency of farming operations.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

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SB Score:121

Glorywebs creates professional websites for businesses to attract customers and increase sales. Our work helps clients build online credibility and showcase their value.

Industry:
Software & Data
Subindustry:
Web Development

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10th

Geneia
SB Score:86

Geneia is an analytic solutions and services company that helps clients improve outcomes, lower cost and restore the Joy of Medicine to physician practice. It simplifies the evolution of value-based care and drives collaboration between health plans, hospitals, providers, and employers. It has a Theon platform that provides analytics, insights and care management solution for health plans, hospitals, providers, and employers that are easy to use, delivers key insights into performance, risk, cost, and utilization, and has predictive capabilities that guide early and targeted interventions to improve outcomes. It was founded in 2006 and is headquartered in Harrisburg, Pennsylvania.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:70

Thought AI transforms traditional analytics by integrating artificial intelligence directly with data, enabling digital information to operate autonomously. This innovative approach eliminates the need for an application layer, streamlining processes and enhancing decision-making for users.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

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Total amount:20

Top 5 Software & Data Startups in Harrisburg for 2025

The top three Software & Data startups in Harrisburg have raised more than USD 110K. Harrisburg startup ecosystem ranks #342 globally for the Software & Data industry.
SB Score:170

Culineer is a mobile app that offers a wide range of delicious food recipes. Users can easily access and follow step-by-step instructions to create mouthwatering dishes. Get ready to explore new culinary experiences and impress your friends and family with your cooking skills.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:121

Glorywebs creates professional websites for businesses to attract customers and increase sales. Our work helps clients build online credibility and showcase their value.

Industry:
Software & Data
Subindustry:
Web Development

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:86

Geneia is an analytic solutions and services company that helps clients improve outcomes, lower cost and restore the Joy of Medicine to physician practice. It simplifies the evolution of value-based care and drives collaboration between health plans, hospitals, providers, and employers. It has a Theon platform that provides analytics, insights and care management solution for health plans, hospitals, providers, and employers that are easy to use, delivers key insights into performance, risk, cost, and utilization, and has predictive capabilities that guide early and targeted interventions to improve outcomes. It was founded in 2006 and is headquartered in Harrisburg, Pennsylvania.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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Regional Rank (North America)

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Total amount:5

Top 2 Edtech Startups in Harrisburg for 2025

Harrisburg startup ecosystem ranks among the top 10 locations in the world for startups in Edtech, holding the falseth position.
SB Score:70

Thought AI transforms traditional analytics by integrating artificial intelligence directly with data, enabling digital information to operate autonomously. This innovative approach eliminates the need for an application layer, streamlining processes and enhancing decision-making for users.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

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Regional Rank (North America)

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SB Score:53

Commonwealth Gaming helps navigate permitting issues and applications, offering assistance through email or phone. For clear and engaging information, reach out for support with startup processes.

Industry:
Edtech
Subindustry:
Edtech

National Rank (United States)

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Regional Rank (North America)

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Total amount:2

Top 2 Marketing & Sales Startups in Harrisburg for 2025

Harrisburg startup ecosystem ranks among the top 10 locations in the world for startups in Marketing & Sales, holding the falseth position.
SB Score:44

Speece Technologies delivers custom technology solutions, including full-stack web development, app development, and digital marketing services, to clients seeking tailored solutions for their business needs.

Industry:
Marketing & Sales
Subindustry:
Digital Marketing

National Rank (United States)

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Regional Rank (North America)

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SB Score:23

A Mighty Group offers a range of marketing services including advertising, web design, brand development, and digital marketing. Specializing in TV and radio advertising, they also provide auto and live surveys, direct mail marketing, and app design to help businesses grow and succeed.

Industry:
Marketing & Sales
Subindustry:
Adtech

National Rank (United States)

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Regional Rank (North America)

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Total amount:2

Most Funded Startups in Harrisburg for 2025

The top three most funded startups in Harrisburg have raised total funding of more than USD 62.3M. MacuLogix has 11.07% more funding than Pledge It.
SB Score:392

MacuLogix focuses on detecting and tracking age-related macular degeneration. It leverages the science of dark adaptation to help eliminate preventable blindness caused by AMD. Through its AdaptDx® dark adaptometer, MacuLogix enables eye care professionals to detect, monitor, and start treating AMD three years before it can be seen in order to prevent vision loss.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:440

Pledge It empowers athletes to raise funds for their team or cause through performance-based fundraising. Athletes can set goals and supporters can pledge donations based on their achievements.

Industry:
Fintech
Subindustry:
Fintech-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:253

Elephant Energy simplifies the transition to a gas-free home by offering modern, all-electric heating and cooling systems, as well as appliances. Their services include heat pumps, water heaters, and EV charging solutions, making it easy for homeowners to upgrade to energy-efficient technologies.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:20

Top Hiring Startups in Harrisburg by Employee Number

The top three hiring startups in Harrisburg have an median employee size that is between [101-250]
SB Score:392

MacuLogix focuses on detecting and tracking age-related macular degeneration. It leverages the science of dark adaptation to help eliminate preventable blindness caused by AMD. Through its AdaptDx® dark adaptometer, MacuLogix enables eye care professionals to detect, monitor, and start treating AMD three years before it can be seen in order to prevent vision loss.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:440

Pledge It empowers athletes to raise funds for their team or cause through performance-based fundraising. Athletes can set goals and supporters can pledge donations based on their achievements.

Industry:
Fintech
Subindustry:
Fintech-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:253

Elephant Energy simplifies the transition to a gas-free home by offering modern, all-electric heating and cooling systems, as well as appliances. Their services include heat pumps, water heaters, and EV charging solutions, making it easy for homeowners to upgrade to energy-efficient technologies.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:121

Glorywebs creates professional websites for businesses to attract customers and increase sales. Our work helps clients build online credibility and showcase their value.

Industry:
Software & Data
Subindustry:
Web Development

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:20

Explore the Startup Ecosystem of Harrisburg

National Rank

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Regional Rank

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156th

4

Global Rank

(WorldWide)

466th

21

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
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1
37.971
00.00
00.00
00.00
9th
0
24th
-
2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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