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Top Startup Exits in Durham for 2026

In Durham, we rank 4 startup exits based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Startup exits in Durham are falling behind the performance of their global counterparts.

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Top Startup Exits in Durham for 2026

1st
Brii BioSciences logo
Brii BioSciencesSB Score: 407Public Exit

Brii Biosciences is a biotechnology cmpany focusing on accelerating innovation and optimizing access to the latest medicines for Chinese patients.

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Website
briibio.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$415M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
NET Power logo
NET PowerSB Score: 388Public Exit

NET Power is a clean energy technology company with a mission to globally deploy affordable and reliable zero-emissions energy solutions. The Company licenses its proprietary NET Power Cycle, which transforms natural gas into low-cost, clean power that's available 24/7. Founded in 2010 and headquartered in Durham, North Carolina, NET Power is driving global adoption by partnering with power producers, technology providers, investors and other innovators to deliver utility-scale plants.

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Website
www.netpower.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$150M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Thryv logo
ThryvSB Score: 345Public Exit

A fitness profile, similar to an electronic medical record, which individuals can use with trainers, gyms, consumer devices, and apps. We will work towards becoming a standard platform by first providing a website and app personal trainers use to manage clients. However, records are owned by clients and persist when their training service ends.

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Website
www.thryv.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:4

Largest Startup Exits in Durham by Funding

The top three largest startup exits in Durham have raised total funding of more than USD 0. Among the top three funded exits, the most popular industry, based on total funding, is Healthtech.
1st
Parata Systems logo
Parata SystemsSB Score: 134Public Exit

Parata Systems provides pharmacy automation solutions in the United States.

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Website
www.parata.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
NET Power logo
NET PowerSB Score: 388Public Exit

NET Power is a clean energy technology company with a mission to globally deploy affordable and reliable zero-emissions energy solutions. The Company licenses its proprietary NET Power Cycle, which transforms natural gas into low-cost, clean power that's available 24/7. Founded in 2010 and headquartered in Durham, North Carolina, NET Power is driving global adoption by partnering with power producers, technology providers, investors and other innovators to deliver utility-scale plants.

View Full Page
Website
www.netpower.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$150M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Brii BioSciences logo
Brii BioSciencesSB Score: 407Public Exit

Brii Biosciences is a biotechnology cmpany focusing on accelerating innovation and optimizing access to the latest medicines for Chinese patients.

View Full Page
Website
briibio.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$415M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:4

Top Hiring Startup Exits in Durham by Employee Size

The top three hiring startup exits in Durham have an average employee size that is smaller than to the global average. Among these, the Software & Data industry features the startup exit with the largest workforce.
1st
Thryv logo
ThryvSB Score: 345Public Exit

A fitness profile, similar to an electronic medical record, which individuals can use with trainers, gyms, consumer devices, and apps. We will work towards becoming a standard platform by first providing a website and app personal trainers use to manage clients. However, records are owned by clients and persist when their training service ends.

View Full Page
Website
www.thryv.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Brii BioSciences logo
Brii BioSciencesSB Score: 407Public Exit

Brii Biosciences is a biotechnology cmpany focusing on accelerating innovation and optimizing access to the latest medicines for Chinese patients.

View Full Page
Website
briibio.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$415M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
NET Power logo
NET PowerSB Score: 388Public Exit

NET Power is a clean energy technology company with a mission to globally deploy affordable and reliable zero-emissions energy solutions. The Company licenses its proprietary NET Power Cycle, which transforms natural gas into low-cost, clean power that's available 24/7. Founded in 2010 and headquartered in Durham, North Carolina, NET Power is driving global adoption by partnering with power producers, technology providers, investors and other innovators to deliver utility-scale plants.

View Full Page
Website
www.netpower.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$150M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Parata Systems logo
Parata SystemsSB Score: 134Public Exit

Parata Systems provides pharmacy automation solutions in the United States.

View Full Page
Website
www.parata.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:4

Explore More Top Startups

Explore the Startup Ecosystem of Durham

National Rank

(United States)

new

Regional Rank

(North America)

18th

1

Global Rank

(WorldWide)

44th

5

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2026 National Rank CityGlobal RankTotal Score & National ShareAnnual Growth

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Quantity Score
Quality ScoreBusiness Score
1st
0
1st
0
935.32535.2%
0.0%
00.00
00.00
00.00
2nd
0
2nd
0
352.15913.3%
0.0%
00.00
00.00
00.00
3rd
0
4th
0
152.3715.7%
0.0%
00.00
00.00
00.00
4th
0
5th
+
1
127.1194.8%
0.0%
00.00
00.00
00.00
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