StartupBlink

258 Top startups in Durham for July 2026

We rank Wolfspeed, Teamworks and ServiceTrade in Durham along with 255 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Durham is part of Raleigh Durham startup ecosystem which ranks #44 globally and #18 in North America.

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Best Startups in Durham for 2026

1st
Wolfspeed logo
WolfspeedSB Score: 573

Wolfspeed is a premier provider of SiC-based power and GaN-on-SiC-based RF power solutions. This also includes the related core competencies in wafer substrate manufacturing for SiC, as well as for SiC with a monocrystalline GaN layer for RF power applications. With these competencies, more than 550 highly skilled employees and a strong IP portfolio of approximately 2,000 patents and patent applications, this deal complements Infineon's previous acquisition of International Rectifier in early 2015. Wolfspeed's SiC-based product portfolio ideally adds to Infineon's offering.

View Full Page
Website
www.wolfspeed.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$780M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Teamworks logo
TeamworksSB Score: 545

Teamworks is a privately held software company that provides a centralized platform for sports organizations to manage operations, communication, and athlete engagement. Its suite of applications supports functions such as logistics coordination, recruiting, compliance, performance nutrition, and athlete development. The company serves a diverse clientele, including collegiate and professional sports teams, Olympic and national governing bodies, as well as military and tactical units.​

View Full Page
Website
www.teamworks.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$422.2M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
ServiceTrade logo
ServiceTradeSB Score: 492

We're here to help service delivery companies focus on what they do best. Delivering great service at a great price. With smart phones in every pocket and rising customer demand for better visibility, ServiceTrade has the answer for incredible customer service. What we can do for your service business?

View Full Page
Website
servicetrade.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$34.1M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Carpe logo
CarpeSB Score: 483

Carpe manufactures an over-the-counter antiperspirant hand and foot lotion that is dermatologist-recommended, 100% non-irritating, and clinically proven to help reduce sweat.

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Website
www.mycarpe.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$2.3M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
5th
ProcessMaker logo
ProcessMakerSB Score: 473

ProcessMaker develops and markets enterprise business process management (BPM) software Larger enterprise customers who require highly customised solutions can also get customer support, training, and professional services from the organisation. The company's flagship Low-Code BPM software is noted for its ease of use and significant customization capabilities.

View Full Page
Website
www.processmaker.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$45M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
6th
Metabolon logo
MetabolonSB Score: 462

Metabolon is a technology company, that develops analytical methods and software for biomarker discovery using metabolomics. Metabolon's expertise in data and translational science enables customers and partners to tackle some of the most complex and urgent questions in the life sciences, thereby accelerating research and improving development outcomes. The company provides scalable and customizable multiomics solutions, including metabolomics and lipidomics, to support customer needs from discovery through clinical trials and throughout the product lifecycle. The company aims to provide biochemical data and insights that broaden and hasten the impact of life sciences research, while also integrating seamlessly with other 'omics' technologies.

View Full Page
Website
www.metabolon.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$207.2M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
7th
Gradient Health logo
Gradient HealthSB Score: 455

Gradient Health, based in Durham, North Carolina, is on a mission to categorize global medical images by pathology. Established in 2018, the company is dedicated to providing clear and accurate labeling for the healthcare industry.

View Full Page
Website
gradienthealth.io
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$100.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
8th
GoTriangle logo
GoTriangleSB Score: 450

GoTriangle is a partnership of public transportation agencies, and organizations funded to promote commuter benefits in the Triangle. The purpose of the GoTriangle.org website is to help people easily find all the information they need to get out from behind the steering wheel and find other travel options that are safe, convenient, inexpensive, more sustainable. All centrally located in one online resource. GoTriangle is a family of transportation services that work together to promote sustainable travel and provide useful resources, including a Trip Planner, transit maps, fares and alerts, teleworking info, & guides to biking & walking in the Triangle.

View Full Page
Website
www.gotriangle.org
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$20M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
9th
Higharc logo
HigharcSB Score: 448

Higharc is the all-in-one web platform that simplifies, connects, and improves each step of design, construction, and sales for home building. It enables builders to design, sell in 3D, and get permit-ready construction documents — all in a single platform. Higharc is on a mission to help builders create better homes and communities, more affordably.

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Website
www.higharc.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$80M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
10th
Precision BioSciences logo

Precision BioSciences is a biotechnology company dedicated to improving lives through its next-generation gene editing technology, ARCUS. Precision BioSciences’ mission is to translate the world’s most powerful genome editing technology into greatly needed products throughout the life sciences. Precision’s proprietary ARCUS genome editing technology enables the production of highly specific nucleases that can insert, remove, and modify DNA at essentially any location in a complex genome.

View Full Page
Website
precisionbiosciences.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$135.7M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
11th
Pairwise Plants logo
Pairwise PlantsSB Score: 436

Pairwise is a purpose-driven food+tech company dedicated to building a healthier world through better fruits and vegetables. Founded in 2017 by Drs. David Liu, Feng Zhang, J. Keith Joung, Tom Adams, and Haven Baker, Pairwise holds licenses from Harvard and Massachusetts General Hospital to base editing and high-fidelity enzymes, and has an expanding internal portfolio of tools and traits. The Pairwise team is growing new types of fruits and vegetables, including leafy greens, berries, and stonefruit, with the first products expected within a few years. The Pairwise team is comprised of leaders in agriculture, CPG food, and research and development.

View Full Page
Website
pairwise.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$155M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:160

Most Funded Startups in Durham for 2026

The top three most funded startups in Durham have raised total funding of more than USD 1.48B. Wolfspeed has 0.85% more funding than Teamworks.
1st
Wolfspeed logo
WolfspeedSB Score: 573

Wolfspeed is a premier provider of SiC-based power and GaN-on-SiC-based RF power solutions. This also includes the related core competencies in wafer substrate manufacturing for SiC, as well as for SiC with a monocrystalline GaN layer for RF power applications. With these competencies, more than 550 highly skilled employees and a strong IP portfolio of approximately 2,000 patents and patent applications, this deal complements Infineon's previous acquisition of International Rectifier in early 2015. Wolfspeed's SiC-based product portfolio ideally adds to Infineon's offering.

View Full Page
Website
www.wolfspeed.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$780M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Teamworks logo
TeamworksSB Score: 545

Teamworks is a privately held software company that provides a centralized platform for sports organizations to manage operations, communication, and athlete engagement. Its suite of applications supports functions such as logistics coordination, recruiting, compliance, performance nutrition, and athlete development. The company serves a diverse clientele, including collegiate and professional sports teams, Olympic and national governing bodies, as well as military and tactical units.​

View Full Page
Website
www.teamworks.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$422.2M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
restor3d logo
restor3dSB Score: 417

Restor3d enables surgeons to improve the reconstruction and repair of the human body through 3D printed implants. The company leverages artificial intelligence to optimize the design and functionality of its implants, aiming for better anatomical fit and patient outcomes. The firm possesses exclusive knowledge and intellectual assets related to 3D printing of osseointegrative substances, AI-driven planning and design automation tools, as well as digital health solutions aimed at delivering integrated, data-supported care to enhance individual patient results.

View Full Page
Website
www.restor3d.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$276.7M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:160

Top Hiring Startups in Durham by Employee Number

The top three hiring startups in Durham have an median employee size that is between [1001-5000]
1st
Wolfspeed logo
WolfspeedSB Score: 573

Wolfspeed is a premier provider of SiC-based power and GaN-on-SiC-based RF power solutions. This also includes the related core competencies in wafer substrate manufacturing for SiC, as well as for SiC with a monocrystalline GaN layer for RF power applications. With these competencies, more than 550 highly skilled employees and a strong IP portfolio of approximately 2,000 patents and patent applications, this deal complements Infineon's previous acquisition of International Rectifier in early 2015. Wolfspeed's SiC-based product portfolio ideally adds to Infineon's offering.

View Full Page
Website
www.wolfspeed.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$780M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Gradient Health logo
Gradient HealthSB Score: 455

Gradient Health, based in Durham, North Carolina, is on a mission to categorize global medical images by pathology. Established in 2018, the company is dedicated to providing clear and accurate labeling for the healthcare industry.

View Full Page
Website
gradienthealth.io
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$100.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Emvenio Research logo
Emvenio ResearchSB Score: 435

Emvenio Research develops decentralized trial solutions to improve clinical trial access to underserved and high-risk populations. Its mission is to eliminate the barriers to clinical trials by bringing access to people where they live, work, and are willing to engage.

View Full Page
Website
emvenio.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$9.2M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Archaius logo
ArchaiusSB Score: 203

Play is a consumer-focused mobile network operator in Poland with over 15 million subscribers. It provides mobile voice, messaging, data, and video services for both consumers and businesses on a contract and prepaid basis under the umbrella brand Play.

View Full Page
Website
archaius.net
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:258

Explore More Top Startups

Explore the Startup Ecosystem of Durham

National Rank

(United States)

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Regional Rank

(North America)

18th

1

Global Rank

(WorldWide)

44th

5

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2026 National Rank CityGlobal RankTotal Score & National ShareAnnual Growth

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