79 Top startups in Tucson for April 2025

We rank Direct.me, Fangamer and Try Your Best in Tucson along with 76 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Tucson startup ecosystem ranks #309 globally and #87 in United States.

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Best Startups in Tucson for 2025

SB Score:446

Direct.me is an innovative online platform that empowers influencers and businesses to showcase and promote their digital presence. By centralizing all online activities, it simplifies the way users connect, engage, and grow their audiences, enhancing their overall online visibility and impact.

Industry:
Software & Data
Subindustry:
SaaS

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SB Score:444

This company specializes in creating unique video game merchandise. They offer a variety of products inspired by popular games, perfect for passionate gamers looking to showcase their favorite franchises.

Industry:
Social & Leisure
Subindustry:
Gaming

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SB Score:431

Try Your Best is a blockchain technology company that empowers businesses to enhance their operations with innovative solutions. By leveraging decentralized systems, it enables secure transactions, improved transparency, and streamlined processes, driving efficiency and trust across various industries.

Industry:
Fintech
Subindustry:
Blockchain

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SB Score:430

A transformative SaaS platform that helps charities create and manage impactful fundraising events. From start to finish, users can easily plan and execute unforgettable experiences that drive donations and support their cause.

Industry:
Social & Leisure
Subindustry:
Communities

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5th

weed
SB Score:392

Weed is an informative platform dedicated to the cannabis industry, emphasizing its health effects and societal impact. As a member of the Contrib Network, it was established through a collaboration between Global Ventures and ZCapital, aiming to provide valuable insights into cannabis-related topics.

Industry:
Social & Leisure
Subindustry:
Communities

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SB Score:376

Pyx Health is a mobile app that combats loneliness by connecting users with supportive communities. It offers a solution to social isolation, fostering meaningful connections and improving overall well-being.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:376

Phantom Space specializes in advanced space transportation technology, encompassing satellites, propulsion systems, and launch vehicles. Their cutting-edge solutions are reshaping the future of space exploration.

Industry:
Transportation
Subindustry:
Aerospace

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SB Score:373

Azuro is a decentralized betting protocol that uses smart contracts to ensure transparency in betting. With a wide range of markets, liquidity, and unique features like collectible bets and NFT gamification, Azuro offers a modern betting experience for users worldwide.

Industry:
Fintech
Subindustry:
Blockchain

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SB Score:360

World View Enterprises offers cutting-edge flight technologies for a breathtaking view of Earth from the edge of space. Experience a unique perspective of our planet like never before.

Industry:
Transportation
Subindustry:
Aerospace

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SB Score:352

PitchVantage utilizes AI to provide real-time feedback on presentation skills, offering a seamless e-learning experience. Perfect your public speaking with instant analysis and personalized tips.

Industry:
Edtech
Subindustry:
Edtech

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SB Score:341

NVX-108 is an oxygen therapeutic for life-threatening conditions like cancer and heart attack. Previously approved in Europe as an ultrasound contrast agent, it's now ready for human clinical trials after successful animal studies. Safe in humans and effective in treating ischemic/hypoxic diseases, this startup is poised for success.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:79

Top 17 Healthtech Startups in Tucson for 2025

The top three Healthtech startups in Tucson have raised more than USD 124M. Tucson startup ecosystem ranks #191 globally for the Healthtech industry.
SB Score:376

Pyx Health is a mobile app that combats loneliness by connecting users with supportive communities. It offers a solution to social isolation, fostering meaningful connections and improving overall well-being.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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SB Score:341

NVX-108 is an oxygen therapeutic for life-threatening conditions like cancer and heart attack. Previously approved in Europe as an ultrasound contrast agent, it's now ready for human clinical trials after successful animal studies. Safe in humans and effective in treating ischemic/hypoxic diseases, this startup is poised for success.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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SB Score:310

This company provides digital communities, health tracking technology, and synbiotic supplements with CBD for menopausal women. Join us for support, tracking, and wellness with natural supplements.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Total amount:17

Top 15 Software & Data Startups in Tucson for 2025

The top three Software & Data startups in Tucson have raised more than USD 8.45M. Tucson startup ecosystem ranks #439 globally for the Software & Data industry.
SB Score:446

Direct.me is an innovative online platform that empowers influencers and businesses to showcase and promote their digital presence. By centralizing all online activities, it simplifies the way users connect, engage, and grow their audiences, enhancing their overall online visibility and impact.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:295

Metropia uses behavioral economics to help drivers choose better departure times, routes, and modes, optimizing transportation systems for smoother travel.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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YourCoach Health serves as a dynamic operating system for behavior change, empowering users to adopt healthier habits and achieve their wellness goals. By providing personalized guidance and support, it transforms the journey toward a healthier lifestyle into an engaging and manageable experience.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

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Regional Rank (North America)

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Total amount:15

Top 6 Edtech Startups in Tucson for 2025

The top three Edtech startups in Tucson have raised more than USD 1.22M. Tucson startup ecosystem ranks #182 globally for the Edtech industry.
SB Score:352

PitchVantage utilizes AI to provide real-time feedback on presentation skills, offering a seamless e-learning experience. Perfect your public speaking with instant analysis and personalized tips.

Industry:
Edtech
Subindustry:
Edtech

National Rank (United States)

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SB Score:131

ClassEquity empowers students with essential financial knowledge for the future. Our mission is to ensure all students have access to financial literacy education. Join us in preparing the next generation for success.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

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SB Score:101

HBM Prenscia empowers engineers with advanced technology and software solutions to analyze data efficiently and make informed decisions. As a global leader in reliability, durability, and performance engineering, HBM Prenscia offers a range of products and services to support engineering professionals worldwide.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

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Total amount:6

Most Funded Startups in Tucson for 2025

The top three most funded startups in Tucson have raised total funding of more than USD 275M. World View Enterprises has 0.67% more funding than Phantom Space.
SB Score:360

World View Enterprises offers cutting-edge flight technologies for a breathtaking view of Earth from the edge of space. Experience a unique perspective of our planet like never before.

Industry:
Transportation
Subindustry:
Aerospace

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:376

Phantom Space specializes in advanced space transportation technology, encompassing satellites, propulsion systems, and launch vehicles. Their cutting-edge solutions are reshaping the future of space exploration.

Industry:
Transportation
Subindustry:
Aerospace

National Rank (United States)

0

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Regional Rank (North America)

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SB Score:279

Aqualung Therapeutics is creating a groundbreaking monoclonal antibody treatment for severe inflammation. Their innovative approach targets uncontrolled inflammation to help improve patient outcomes.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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Total amount:79

Top Hiring Startups in Tucson by Employee Number

The top three hiring startups in Tucson have an median employee size that is between [101-250]
SB Score:101

HBM Prenscia empowers engineers with advanced technology and software solutions to analyze data efficiently and make informed decisions. As a global leader in reliability, durability, and performance engineering, HBM Prenscia offers a range of products and services to support engineering professionals worldwide.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:444

This company specializes in creating unique video game merchandise. They offer a variety of products inspired by popular games, perfect for passionate gamers looking to showcase their favorite franchises.

Industry:
Social & Leisure
Subindustry:
Gaming

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:376

Pyx Health is a mobile app that combats loneliness by connecting users with supportive communities. It offers a solution to social isolation, fostering meaningful connections and improving overall well-being.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:270

Tucson Tamale delivers delicious tamales to selected areas for free and offers convenient curbside pickup. Enjoy gourmet tamales with ease from this food production company.

Industry:
Foodtech
Subindustry:
Food and Beverage

National Rank (United States)

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Total amount:79

Explore the Startup Ecosystem of Tucson

National Rank

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Regional Rank

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101st

3

Global Rank

(WorldWide)

309th

9

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
-
1
37.971
00.00
00.00
00.00
9th
0
24th
-
2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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