52 Top startups in Mannheim for April 2025

We rank OSAPIENS, alugha and CYANITE in Mannheim along with 49 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Mannheim startup ecosystem ranks #152 globally and #5 in Germany.

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Best Startups in Mannheim for 2025

SB Score:498

Osapiens, a fast-growing company based in Mannheim, Germany, is dedicated to advancing corporate sustainability. By providing innovative solutions, Osapiens empowers businesses to adopt eco-friendly practices and enhance their environmental impact, driving meaningful change in the corporate world.

Industry:
Software & Data
Subindustry:
Software

National Rank (Germany)

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SB Score:464

With alugha it becomes very easy to transform your video into a multilingual video. With an all in one place solution for transcribing, creating subtitles, translate and dub videos within every modern browser it is as easy as never before. You can invite anyone also with just a smartphone to join the project for just a specific language. With a global CDN Network, unlimited object storage a state-of-the-art html5 video player and 10,000 of multilingual videos which most is about free education and edutainment you will find the best place to position yourself and your videos to a highly interested community.

Industry:
Social & Leisure
Subindustry:
Entertainment

National Rank (Germany)

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Regional Rank (Western Europe)

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SB Score:373

This AI-powered SaaS platform revolutionizes the music industry by providing advanced analytics and personalized recommendations for artists and labels. It helps users optimize their music promotion strategies and connect with their target audience more effectively.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (Germany)

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SB Score:363

Hey Holy is a pet food manufacturer that specializes in nutritious products for dogs. By incorporating natural ingredients alongside essential vitamins and minerals, they create tasty options free from sugar additives and harmful preservatives, all conveniently available for online shopping.

Industry:
Social & Leisure
Subindustry:
Communities

National Rank (Germany)

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SB Score:359

This startup enables businesses to respond to customer reviews three times faster with personalized replies crafted by an AI assistant. Integration is seamless through their app or APIs. Users can sign up for free to efficiently manage customer feedback and enhance their engagement in no time.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:326

Facilitating cancer and stem cell research, drug discovery, toxicology, and tissue engineering, Cellitate's polymeric platforms improve cellular interaction for enhanced cell culture in biological research.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (Germany)

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Regional Rank (Western Europe)

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1000 Satellites Coworking offers leased office spaces for corporate employers, individuals, and startups, creating a productive work environment. Join us for a collaborative workspace that fosters creativity and productivity.

Industry:
Social & Leisure
Subindustry:
Communities

National Rank (Germany)

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SB Score:294

Spotted is a hyperlocal app that helps users connect with amazing people in their daily lives. It facilitates making new connections and forming relationships with those around you.

Industry:
Software & Data
Subindustry:
Apps

National Rank (Germany)

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SB Score:282

Hycube offers top-tier renewable energy storage solutions, revolutionizing the engineering industry. Their cutting-edge technology provides superior energy storage capabilities for a sustainable future.

Industry:
Energy & Environment
Subindustry:
Clean Energy

National Rank (Germany)

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SB Score:279

PracticallyArzt is a dynamic job exchange platform dedicated to connecting medical professionals with a diverse array of doctor vacancies. It offers vital news, resources, and services tailored for careers in the medical field, while also serving the pharmaceutical industry effectively.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:256

CloudRail has developed a uniform API for technically similar services, from social networks to various cloud storage devices. The same applies to IoT devices that can be networked via CloudRail.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (Germany)

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Regional Rank (Western Europe)

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Total amount:52

Top 26 Software & Data Startups in Mannheim for 2025

The top three Software & Data startups in Mannheim have raised more than USD 299M. Mannheim startup ecosystem ranks #90 globally for the Software & Data industry.
SB Score:498

Osapiens, a fast-growing company based in Mannheim, Germany, is dedicated to advancing corporate sustainability. By providing innovative solutions, Osapiens empowers businesses to adopt eco-friendly practices and enhance their environmental impact, driving meaningful change in the corporate world.

Industry:
Software & Data
Subindustry:
Software

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:373

This AI-powered SaaS platform revolutionizes the music industry by providing advanced analytics and personalized recommendations for artists and labels. It helps users optimize their music promotion strategies and connect with their target audience more effectively.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:359

This startup enables businesses to respond to customer reviews three times faster with personalized replies crafted by an AI assistant. Integration is seamless through their app or APIs. Users can sign up for free to efficiently manage customer feedback and enhance their engagement in no time.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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Total amount:26

Top 4 Healthtech Startups in Mannheim for 2025

The top three Healthtech startups in Mannheim have raised more than USD 13.6M. Mannheim startup ecosystem ranks #144 globally for the Healthtech industry.
SB Score:326

Facilitating cancer and stem cell research, drug discovery, toxicology, and tissue engineering, Cellitate's polymeric platforms improve cellular interaction for enhanced cell culture in biological research.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (Germany)

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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SB Score:234

Vibrosonic GmbH creates high-quality hearing solutions that are completely invisible when worn. Their innovative products are designed to provide premium sound quality without compromising on discretion.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (Germany)

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Regional Rank (Western Europe)

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SB Score:128

APONTIS PHARMA specializes in bridging connections for chronic disorder patients, focusing on diabetes, cardiovascular, and respiratory diseases like COPD. They are experts in mediation and support, facilitating relationships and providing valuable knowledge in these areas.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (Germany)

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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Total amount:4

Top 1 Fintech Startups in Mannheim for 2025

Mannheim startup ecosystem ranks #208 globally for the Fintech industry.
SB Score:98

Introducing a lending bot for Bitfinex, Quoinex, and Poloniex. Easily lend and borrow cryptocurrency with automated assistance. Maximize your potential profits with seamless and efficient transactions.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Germany)

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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Total amount:1

Most Funded Startups in Mannheim for 2025

The top three most funded startups in Mannheim have raised total funding of more than USD 306M. OSAPIENS has 8.22% more funding than Spotted.
SB Score:498

Osapiens, a fast-growing company based in Mannheim, Germany, is dedicated to advancing corporate sustainability. By providing innovative solutions, Osapiens empowers businesses to adopt eco-friendly practices and enhance their environmental impact, driving meaningful change in the corporate world.

Industry:
Software & Data
Subindustry:
Software

National Rank (Germany)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:294

Spotted is a hyperlocal app that helps users connect with amazing people in their daily lives. It facilitates making new connections and forming relationships with those around you.

Industry:
Software & Data
Subindustry:
Apps

National Rank (Germany)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:464

With alugha it becomes very easy to transform your video into a multilingual video. With an all in one place solution for transcribing, creating subtitles, translate and dub videos within every modern browser it is as easy as never before. You can invite anyone also with just a smartphone to join the project for just a specific language. With a global CDN Network, unlimited object storage a state-of-the-art html5 video player and 10,000 of multilingual videos which most is about free education and edutainment you will find the best place to position yourself and your videos to a highly interested community.

Industry:
Social & Leisure
Subindustry:
Entertainment

National Rank (Germany)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
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Total amount:52

Top Hiring Startups in Mannheim by Employee Number

The top three hiring startups in Mannheim have an median employee size that is between [251-500]
SB Score:498

Osapiens, a fast-growing company based in Mannheim, Germany, is dedicated to advancing corporate sustainability. By providing innovative solutions, Osapiens empowers businesses to adopt eco-friendly practices and enhance their environmental impact, driving meaningful change in the corporate world.

Industry:
Software & Data
Subindustry:
Software

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:104

RAD-x runs medical service companies focusing on diagnostic imaging and nuclear medicine. Their services provide advanced diagnostic tools for healthcare professionals, ensuring accurate and timely medical assessments.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (Germany)

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Regional Rank (Western Europe)

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SB Score:216

Klarsolar is a dedicated photovoltaic provider specializing in solar energy solutions. They offer comprehensive consulting, planning, and installation services, ensuring customers receive expert guidance at every stage. For inquiries, their contact information is readily available on their website, making it easy to connect with their team.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:128

APONTIS PHARMA specializes in bridging connections for chronic disorder patients, focusing on diabetes, cardiovascular, and respiratory diseases like COPD. They are experts in mediation and support, facilitating relationships and providing valuable knowledge in these areas.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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Total amount:52

Explore the Startup Ecosystem of Mannheim

National Rank

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Regional Rank

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38th

2

Global Rank

(WorldWide)

152nd

4

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Top Cities for Startups in Germany - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
13th
-
2
49.918
00.00
00.00
00.00
2nd
0
39th
-
5
21.959
00.00
00.00
00.00
3rd
0
98th
-
8
8.060
00.00
00.00
00.00
4th
+
1
134th
+
26
5.112
00.00
00.00
00.00
5th
-
1
152nd
-
4
4.237
00.00
00.00
00.00
6th
0
154th
+
12
4.149
00.00
00.00
00.00
7th
+
1
163rd
+
25
3.886
00.00
00.00
00.00
8th
+
1
178th
+
26
3.244
00.00
00.00
00.00
9th
-
2
206th
-
24
2.481
00.00
00.00
00.00
10th
+
5
225th
+
40
2.084
00.00
00.00
00.00
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