293 Top startups in Cambridge for April 2025

We rank Patients Know Best, Ko-fi and Speechmatics in Cambridge along with 290 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Cambridge startup ecosystem ranks #72 globally and #2 in United Kingdom.

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Top Unicorn Startups in Cambridge for 2025

CMR Surgical is the only unicorn in Cambridge raising more than USD 3B. It is the undefined ranked unicorn in Western Europe.
SB Score:527

CMR Surgical, a UK company, designs and manufactures Versius, a robotic surgery system. Versius enhances precision and efficiency in surgical procedures, revolutionizing the way surgeries are performed.

Industry:
Healthtech
Subindustry:
Medtech

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Total amount:1

Best Startups in Cambridge for 2025

SB Score:548

Patients Know Best is a secure platform for transferring medical data among healthcare settings, people, and devices. Recognized as a leader in patient-controlled records, it solves healthcare fragmentation by empowering patients and enabling integrated care. It serves as a central hub for all healthcare data transactions.

Industry:
Healthtech
Subindustry:
Medtech

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SB Score:517

Ko-fi enables creators—such as illustrators, podcasters, and bloggers—to receive fan support by allowing patrons to donate the cost of a coffee through their Ko-fi page. With just one click, fans can express their appreciation and help fund their favorite content creators' passions.

Industry:
Software & Data
Subindustry:
SaaS

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SB Score:487

The world’s first adaptive, self-organising ‘smart ledger’. Fetch is a next-generation protocol, invented by world-leading AI experts, that enables a digital world where Autonomous Economic Agents can perform proactive economic activity. With unrivalled performance and scalability, Fetch is the missing critical infrastructure for tomorrow’s digital economy.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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Discover a stunning collection of leather satchels and music bags in various sizes, colors, and styles including backpack and shoulder strap options. Perfect for those who appreciate quality and style on the go.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:473

Built on a proprietary Large Language Model (LLM), Luminance brings Legal-Grade™ AI to every touchpoint a business has with its documents, from contract generation to negotiation and post-execution analysis. Developed by world-leading AI experts from the University of Cambridge, Luminance's specialist AI is now used by over 700 organisations in 70 countries working in more than 80 languages. This includes over a quarter of the world's largest law firms, all of the Big Four consultancy firms and multinational organisations including AMD, BBC Studios, LG Chem, Hitachi, Staples and Yokogawa.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:462

Featurespace offers cutting-edge adaptive behavioral analytics technology and automated deep behavioral networks to enhance risk management. Their innovative solutions provide real-time insights and protection against fraudulent activities.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:455

Horizon Discovery Group PLC is a UK life science company that uses gene editing and gene modulation platforms to produce cells, applying them in research and clinical applications that advance human health. The Company’s gene editing and gene modulation platform, are able to alter almost any DNA sequence or RNA transcription, has generated a catalogue of over 1,000,000 cell and reagent products that help researchers recapitulate the genetic and protein anomalies found in diseases like cancer. These models have been adopted by c12, 000 organizations to better understand of the predictors and drivers of disease and drug response, and by Horizon in a range of services offered to customers, as well as in the Company’s own research R&D pipeline.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:448

Bit.bio decodes the genetic makeup of human cells, bridging the gap between coding and biology. Their technology identifies the unique characteristics of each cell, revolutionizing our understanding of cell identity.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:293

Top 104 Healthtech Startups in Cambridge for 2025

The top three Healthtech startups in Cambridge have raised more than USD 1.56B. Cambridge startup ecosystem ranks #28 globally for the Healthtech industry.
SB Score:548

Patients Know Best is a secure platform for transferring medical data among healthcare settings, people, and devices. Recognized as a leader in patient-controlled records, it solves healthcare fragmentation by empowering patients and enabling integrated care. It serves as a central hub for all healthcare data transactions.

Industry:
Healthtech
Subindustry:
Medtech

National Rank (United Kingdom)

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Regional Rank (Western Europe)

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SB Score:455

Horizon Discovery Group PLC is a UK life science company that uses gene editing and gene modulation platforms to produce cells, applying them in research and clinical applications that advance human health. The Company’s gene editing and gene modulation platform, are able to alter almost any DNA sequence or RNA transcription, has generated a catalogue of over 1,000,000 cell and reagent products that help researchers recapitulate the genetic and protein anomalies found in diseases like cancer. These models have been adopted by c12, 000 organizations to better understand of the predictors and drivers of disease and drug response, and by Horizon in a range of services offered to customers, as well as in the Company’s own research R&D pipeline.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United Kingdom)

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SB Score:448

Bit.bio decodes the genetic makeup of human cells, bridging the gap between coding and biology. Their technology identifies the unique characteristics of each cell, revolutionizing our understanding of cell identity.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United Kingdom)

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Regional Rank (Western Europe)

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Total amount:104

Top 89 Software & Data Startups in Cambridge for 2025

The top three Software & Data startups in Cambridge have raised more than USD 547M. Cambridge startup ecosystem ranks #86 globally for the Software & Data industry.
SB Score:517

Ko-fi enables creators—such as illustrators, podcasters, and bloggers—to receive fan support by allowing patrons to donate the cost of a coffee through their Ko-fi page. With just one click, fans can express their appreciation and help fund their favorite content creators' passions.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United Kingdom)

0

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Regional Rank (Western Europe)

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SB Score:487

The world’s first adaptive, self-organising ‘smart ledger’. Fetch is a next-generation protocol, invented by world-leading AI experts, that enables a digital world where Autonomous Economic Agents can perform proactive economic activity. With unrivalled performance and scalability, Fetch is the missing critical infrastructure for tomorrow’s digital economy.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United Kingdom)

0

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Regional Rank (Western Europe)

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Total amount:89

Top 13 Ecommerce & Retail Startups in Cambridge for 2025

The top three Ecommerce & Retail startups in Cambridge have raised more than USD 150M. Cambridge startup ecosystem ranks #81 globally for the Ecommerce & Retail industry.

Discover a stunning collection of leather satchels and music bags in various sizes, colors, and styles including backpack and shoulder strap options. Perfect for those who appreciate quality and style on the go.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:380

Metail is redesigning digital fashion experiences. The company has developed a range of expertise and capabilities in 3D body modeling, garment applications, and outfit visualization as well as size recommendation, AR, and VR garment try-on. Metail is helping brands and manufacturers embed and harness their digital product creation and selling capabilities using compelling visualization to communicate better. As a result, teams experience better collaboration, quicker decision-making, and less waste in taking their products to market.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

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SB Score:369

Zedify is decarbonising the last mile in cities with cargo bikes: over 80% lower carbon and 13% more efficient than the next best alternative, we delight our customers with affordable deliveries that build loyalty to their brands.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Total amount:13

Most Funded Startups in Cambridge for 2025

The top three most funded startups in Cambridge have raised total funding of more than USD 1.74B. Artios Pharma has 0.41% more funding than PragmatIC Semiconductor.
SB Score:357

Artios is an independent DNA Damage Response (DDR) company focused on developing first-in-class treatments for cancer. Established in May 2016, the Company is led by an experienced scientific and leadership team with proven expertise in DDR drug discovery. Artios is building a pipeline of next-generation DDR programs, including through a unique partnership with Cancer Research Technology (CRT), the development and commercialization arm of Cancer Research UK (CRUK), and with leading DNA repair researchers worldwide. The Company’s investors include SV Life Sciences, Merck Ventures, Imperial Innovations, Arix Bioscience PLC, CRT Pioneer Fund (managed by Sixth Element Capital), and AbbVie Ventures. Artios is based at the Babraham Institute in Cambridge, UK.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United Kingdom)

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SB Score:369

CellCentric’s primary programme targets a deubiquitinase (DUB) enzyme which is strongly associated with prostate cancer, a leading cause of mortality among men. The target modulates the androgen receptor pathway and can potentially combat the multiple resistance mechanisms seen with recently approved prostate cancer drugs such Xtandi and Zytiga. The programme also has potential clinical utility in non-small cell lung, breast and colon cancer.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United Kingdom)

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Total amount:293

Top Hiring Startups in Cambridge by Employee Number

The top three hiring startups in Cambridge have an median employee size that is between [5001-10000]

1st

CSR
SB Score:417

CSR is a pioneering designer and developer of silicon and software for the consumer electronics market. We help to transform the lives of motorists, photographers, music lovers, mobile phone users and other gadget-loving consumers. CSR is dedicated to finding simple solutions to complex problems. Using our track record working with leading brands, our highly skilled engineers develop world-class technologies that realise the potential of a wide range of devices to make peoples' lives and experiences easier, richer and more varied. Our energies are focused on five sectors: * Voice and music, including headsets, speakers and docks for high definition wireless experiences * Location, helping to bring the outdoors in and allowing people to find their way around airports or shopping centres for example * Automotive infotainment, driving innovative solutions for the auto industry with the integration of smartphones and in-vehicle systems * Bluetooth® Smart, capitalising on low energy connectivity for a range of devices * Imaging (cameras and printers), delivering integrated connectivity, location and imaging CSR is at the forefront of developing semiconductors and software for a host of world-leading technology platforms and standards, including Bluetooth®, GPS and other location technologies, FM radio, Wi-Fi®, Near Field Communication and numerous others. As the demand for our products has grown, and the range of devices and applications proliferated, we have expanded into new markets including voice, music and gaming. To reinforce our commitment, we have acquired companies in these sectors including SiRF in 2009, aptX® in 2010 and Zoran in 2011.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:344

AVEVA provides innovative engineering IT software for industries such as plants, power, and marine. Their solutions streamline processes and improve efficiency, catering to the specific needs of each sector.

Industry:
Healthtech
Subindustry:
Health-Other

National Rank (United Kingdom)

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Total amount:293

Explore the Startup Ecosystem of Cambridge

National Rank

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Regional Rank

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15th

1

Global Rank

(WorldWide)

72nd

9

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Top Cities for Startups in United Kingdom - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
3rd
0
144.375
00.00
00.00
00.00
2nd
0
72nd
-
9
9.776
00.00
00.00
00.00
3rd
0
85th
0
9.030
00.00
00.00
00.00
4th
0
99th
-
3
7.884
00.00
00.00
00.00
5th
0
119th
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18
6.448
00.00
00.00
00.00
6th
0
121st
-
4
6.171
00.00
00.00
00.00
7th
+
1
168th
+
2
3.733
00.00
00.00
00.00
8th
-
1
172nd
-
14
3.598
00.00
00.00
00.00
9th
0
188th
+
12
2.890
00.00
00.00
00.00
10th
+
2
211th
+
11
2.292
00.00
00.00
00.00
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