1st
CMR SurgicalCMR Surgical, a UK company, designs and manufactures Versius, a robotic surgery system. Versius enhances precision and efficiency in surgical procedures, revolutionizing the way surgeries are performed.
We rank Patients Know Best, Ieso Digital Health and Speechmatics in Cambridge along with 344 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Cambridge startup ecosystem ranks #85 globally and #3 in United Kingdom.
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1st
CMR SurgicalCMR Surgical, a UK company, designs and manufactures Versius, a robotic surgery system. Versius enhances precision and efficiency in surgical procedures, revolutionizing the way surgeries are performed.
Total amount:1

Patients Know Best is the world’s first patient-controlled medical records system. It is a fully secure online tool which enables patients to better organise, manage and control their own health care provision – it also saves the time of physicians through allowing secure, online consultations. Founded by Dr. Mohammad Al-Ubaydli, a physician, programmer and expert in IT in healthcare, Patients Know Best has won social enterprise awards for its focus on patient care. Patients Know Best’s first customers include Great Ormond Street Hospital, St Mark’s Hospital, Novartis and NHS South Devon. Patients Know Best integrates fully into the NHS secure network and is available for use by any patient with any clinician anywhere in the world. Patients Know Best complies fully with UK NHS and data protection requirements as well as the EU data protection act and US HIPAA legislation for dealing with medical data.
Provides digital therapy solutions to improve mental health outcomes.
3rd
SpeechmaticsSpeechmatics exists to understand every voice. Offering its speech-to-text API engine for solution and service providers to integrate into their stack irrespective of their industry or use case. Businesses use Speechmatics around the world to accurately understand and transcribe human-level speech into text regardless of demographic, age, gender, accent, dialect or location
Pragmatic is a ultra-low-cost flexible electronics. Their flexible integrated circuits (FlexICs) are thinner than human hair and can be invisibly embedded in objects, enabling innovators to create novel solutions to everyday problems that are not practical with conventional electronics. Designers can create their own application-specific flexible devices using our FlexIC Foundry® service at a fraction of the cost and time required for traditional silicon circuits, opening up multiple new markets. We also offer standard FlexIC products that extend proven applications such as RFID and NFC into mass market use cases, enabling the potential for trillions of smart objects that can engage with consumers and their environments. All FlexICs are manufactured on our revolutionary FlexLogIC® production system, a highly scalable manufacturing model for cost-effective high-volume production, achieved with orders of magnitude lower capital investment and operating cost compared to a traditional silicon IC fab. Our novel, differentiated technology is being adopted by a growing base of global companies across diverse markets, including consumer goods, retail, healthcare, pharmaceutical, gaming and security. Pragmatic is headquartered in Cambridge, UK, with our first billion-unit production facility in Sedgefield. Shareholders include Cambridge Innovation Capital, Arm and Avery Dennison.

Beautiful leather satchels and music bags in a variety of sizes, colours - backpack or shoulder strap styles. Made in England, the traditional school satchel is back and looking better than ever.
6th
bit.bioBit.bio specializes in the fields of coding and biology that determine the identity of every human cell. Their mission is coding cells for health. To do so, we apply the principles of computation to biology. Bit.bio's current focus is to develop a scalable technology platform capable of producing consistent batches of every human cell. This has the potential to unlock a new generation of medicine: it will enable research and drug discovery to move on from inappropriate models and work with the cells that actually are affected by the human disease. A scalable platform of consistent cells will also be the basis for a new generation of cell and tissue therapies. To achieve our goals, we have assembled a team of pioneers in stem cells, cellular reprogramming, mathematical modeling, and cell therapy. Collaboration is at the heart of bit.bio. We are empirical, highly ambitious, and driven by a common purpose.
7th
LuminanceLuminance develops an AI-powered platform for contract generation, negotiation, and post-execution analysis. Its proprietary legal language model is designed to process and understand legal documents with a focus on accuracy and compliance. The platform combines generative and analytical AI to assist businesses in managing contract-related workflows. Luminance is used by organizations across various industries to streamline legal document review and decision-making.
8th
PitPatPitPat is dedicated to improving animal health and wellbeing through the application of wearables, technology and data. The company designs and manufactures affordable products for pet owners, and creates bespoke solutions for commercial partners. More on pitpat.com

Horizon Discovery Group PLC is a UK life science company that uses gene editing and gene modulation platforms to produce cells, applying them in research and clinical applications that advance human health. The Company’s gene editing and gene modulation platform, are able to alter almost any DNA sequence or RNA transcription, has generated a catalogue of over 1,000,000 cell and reagent products that help researchers recapitulate the genetic and protein anomalies found in diseases like cancer. These models have been adopted by c12, 000 organizations to better understand of the predictors and drivers of disease and drug response, and by Horizon in a range of services offered to customers, as well as in the Company’s own research R&D pipeline.
10th
PillSortedPillSorted aims to provide a personalised way of delivering medication to patients, while setting forth the blueprint for the future of digital pharmacy care.
11th
Nu QuantumNu Quantum develops quantum networking hardware and software that connects multiple quantum processors into a distributed computing architecture designed to scale quantum computing systems beyond single processors. The company creates photonic interfaces and networking units to enable entanglement distribution and modular integration across diverse qubit technologies for scalable quantum computation. Its offerings include systems that weave entanglement links between quantum processing units and support a qubit-agnostic software layer to abstract and manage networked quantum resources. Nu Quantum’s technology supports research and development collaborations with quantum hardware providers and ecosystem partners focused on advancing distributed quantum compute infrastructures.
Total amount:347

Patients Know Best is the world’s first patient-controlled medical records system. It is a fully secure online tool which enables patients to better organise, manage and control their own health care provision – it also saves the time of physicians through allowing secure, online consultations. Founded by Dr. Mohammad Al-Ubaydli, a physician, programmer and expert in IT in healthcare, Patients Know Best has won social enterprise awards for its focus on patient care. Patients Know Best’s first customers include Great Ormond Street Hospital, St Mark’s Hospital, Novartis and NHS South Devon. Patients Know Best integrates fully into the NHS secure network and is available for use by any patient with any clinician anywhere in the world. Patients Know Best complies fully with UK NHS and data protection requirements as well as the EU data protection act and US HIPAA legislation for dealing with medical data.
Provides digital therapy solutions to improve mental health outcomes.
3rd
SpeechmaticsSpeechmatics exists to understand every voice. Offering its speech-to-text API engine for solution and service providers to integrate into their stack irrespective of their industry or use case. Businesses use Speechmatics around the world to accurately understand and transcribe human-level speech into text regardless of demographic, age, gender, accent, dialect or location
Total amount:347

Patients Know Best is the world’s first patient-controlled medical records system. It is a fully secure online tool which enables patients to better organise, manage and control their own health care provision – it also saves the time of physicians through allowing secure, online consultations. Founded by Dr. Mohammad Al-Ubaydli, a physician, programmer and expert in IT in healthcare, Patients Know Best has won social enterprise awards for its focus on patient care. Patients Know Best’s first customers include Great Ormond Street Hospital, St Mark’s Hospital, Novartis and NHS South Devon. Patients Know Best integrates fully into the NHS secure network and is available for use by any patient with any clinician anywhere in the world. Patients Know Best complies fully with UK NHS and data protection requirements as well as the EU data protection act and US HIPAA legislation for dealing with medical data.
Provides digital therapy solutions to improve mental health outcomes.
3rd
SpeechmaticsSpeechmatics exists to understand every voice. Offering its speech-to-text API engine for solution and service providers to integrate into their stack irrespective of their industry or use case. Businesses use Speechmatics around the world to accurately understand and transcribe human-level speech into text regardless of demographic, age, gender, accent, dialect or location
Total amount:347

Patients Know Best is the world’s first patient-controlled medical records system. It is a fully secure online tool which enables patients to better organise, manage and control their own health care provision – it also saves the time of physicians through allowing secure, online consultations. Founded by Dr. Mohammad Al-Ubaydli, a physician, programmer and expert in IT in healthcare, Patients Know Best has won social enterprise awards for its focus on patient care. Patients Know Best’s first customers include Great Ormond Street Hospital, St Mark’s Hospital, Novartis and NHS South Devon. Patients Know Best integrates fully into the NHS secure network and is available for use by any patient with any clinician anywhere in the world. Patients Know Best complies fully with UK NHS and data protection requirements as well as the EU data protection act and US HIPAA legislation for dealing with medical data.
Provides digital therapy solutions to improve mental health outcomes.
3rd
SpeechmaticsSpeechmatics exists to understand every voice. Offering its speech-to-text API engine for solution and service providers to integrate into their stack irrespective of their industry or use case. Businesses use Speechmatics around the world to accurately understand and transcribe human-level speech into text regardless of demographic, age, gender, accent, dialect or location
Total amount:347
Pragmatic is a ultra-low-cost flexible electronics. Their flexible integrated circuits (FlexICs) are thinner than human hair and can be invisibly embedded in objects, enabling innovators to create novel solutions to everyday problems that are not practical with conventional electronics. Designers can create their own application-specific flexible devices using our FlexIC Foundry® service at a fraction of the cost and time required for traditional silicon circuits, opening up multiple new markets. We also offer standard FlexIC products that extend proven applications such as RFID and NFC into mass market use cases, enabling the potential for trillions of smart objects that can engage with consumers and their environments. All FlexICs are manufactured on our revolutionary FlexLogIC® production system, a highly scalable manufacturing model for cost-effective high-volume production, achieved with orders of magnitude lower capital investment and operating cost compared to a traditional silicon IC fab. Our novel, differentiated technology is being adopted by a growing base of global companies across diverse markets, including consumer goods, retail, healthcare, pharmaceutical, gaming and security. Pragmatic is headquartered in Cambridge, UK, with our first billion-unit production facility in Sedgefield. Shareholders include Cambridge Innovation Capital, Arm and Avery Dennison.
Artios Pharma is a biopharmaceutical company that provides new solutions in the DNA damage response (DDR) field through its comprehensive anti-cancer approach and the deep experience of its team of DDR drug developers. Its clinical-stage candidates, ATR inhibitor alnodesertib and DNA Polymerase theta (Polθ) inhibitor ART6043, as well as its preclinical programs, including DDRi-ADCs, are designed with differentiated pharmaceutical properties and novel biological approaches to precisely eliminate a cancer cell’s remaining survival mechanisms.
3rd
CellCentricCellCentric is a clinical-stage biotech company focusing on the inhibition of p300/CBP to treat specific cancers, particularly solid tumors. The programme also has potential clinical utility in non-small cell lung, breast, and colon cancer. The company's oral drug, Inobrodib, is currently in Phase I/II clinical trials and aims to address cancers such as multiple myeloma. The company is committed to science-driven solutions for cancer, with a patient-focused approach to novel therapies.
Total amount:347

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CSRCSR is a pioneering designer and developer of silicon and software for the consumer electronics market. We help to transform the lives of motorists, photographers, music lovers, mobile phone users and other gadget-loving consumers. CSR is dedicated to finding simple solutions to complex problems. Using our track record working with leading brands, our highly skilled engineers develop world-class technologies that realise the potential of a wide range of devices to make peoples' lives and experiences easier, richer and more varied. Our energies are focused on five sectors: * Voice and music, including headsets, speakers and docks for high definition wireless experiences * Location, helping to bring the outdoors in and allowing people to find their way around airports or shopping centres for example * Automotive infotainment, driving innovative solutions for the auto industry with the integration of smartphones and in-vehicle systems * Bluetooth® Smart, capitalising on low energy connectivity for a range of devices * Imaging (cameras and printers), delivering integrated connectivity, location and imaging CSR is at the forefront of developing semiconductors and software for a host of world-leading technology platforms and standards, including Bluetooth®, GPS and other location technologies, FM radio, Wi-Fi®, Near Field Communication and numerous others. As the demand for our products has grown, and the range of devices and applications proliferated, we have expanded into new markets including voice, music and gaming. To reinforce our commitment, we have acquired companies in these sectors including SiRF in 2009, aptX® in 2010 and Zoran in 2011.
2nd
AVEVAAVEVA is an engineering IT software provider to the plant, power, and marine industries. Through 40 years of visionary and continual progression, AVEVA has harnessed the power of information technology and transformed entire industries. It was founded in 1967 and is headquartered in Cambridge, United Kingdom.
Provides digital therapy solutions to improve mental health outcomes.

Frontier was founded in 1994 by David Braben, co-author of the seminal "Elite", to carry forward his groundbreaking work and development ethos into projects with a scale and ambition that only teams of skilled professionals can tackle. David plays a very active role in the company. With a talented team of developers and experienced managers he has helped Frontier successfully to navigate three exciting decades of the ever-changing technology landscape of mass-market gaming platforms and overseen Frontier's emergence as one of the worldwide games industry's leading independent developers. Frontier’s development strengths are immersive, fun gameplay design and unparalleled artistic quality underpinned and enabled by cutting-edge technology development and a talent for getting the best out of hardware and UI. They get their games into customers’ hands by: i) working with a number of top publishers, with whom they have developed long term relationships, and ii) a growing number of self-published titles using digital distribution channels on the major gaming platforms. They are currently over 200 individuals with development studios in Cambridge, UK and Halifax, Canada. They are actively looking to recruit strong candidates, both graduate and industry experienced, in all areas to work on their exciting, diverse mix of projects on cutting-edge gaming platforms.
Total amount:347
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Ko-fiKo-fi enables creators—such as illustrators, podcasters, and bloggers—to receive fan support by allowing patrons to donate the cost of a coffee through their Ko-fi page. With just one click, fans can express their appreciation and help fund their favorite content creators' passions.

Patients Know Best is the world’s first patient-controlled medical records system. It is a fully secure online tool which enables patients to better organise, manage and control their own health care provision – it also saves the time of physicians through allowing secure, online consultations. Founded by Dr. Mohammad Al-Ubaydli, a physician, programmer and expert in IT in healthcare, Patients Know Best has won social enterprise awards for its focus on patient care. Patients Know Best’s first customers include Great Ormond Street Hospital, St Mark’s Hospital, Novartis and NHS South Devon. Patients Know Best integrates fully into the NHS secure network and is available for use by any patient with any clinician anywhere in the world. Patients Know Best complies fully with UK NHS and data protection requirements as well as the EU data protection act and US HIPAA legislation for dealing with medical data.

eLife Sciences is a nonprofit collaboration between funders and researchers that publishes research related to life sciences and biomedicine. eLife is an open-access journal that offers a platform for extending the reach and influence of new discoveries and to showcase new approaches to the presentation, use, and assessment of research. eLife Sciences reviews the research works of early career scientists; provides them with feedback; promotes their works and provides quantitative and qualitative indicators about their reach and influence; and gets media coverage in venues such as the New York Times and National Geographic. It makes every paper accessible to students, colleagues in other fields, and the public through impact statements, plain language summaries such as eLife Digests, and selected expert commentaries such as eLife Insights. eLife Sciences deals with fundamental and theoretical work, through to translational, applied, and clinical research. It publishes research articles, short reports, editorials, and insights on topics such as biochemistry, biophysics and structural biology, cell biology, computational and systems biology, developmental biology and stem cells, ecology, epidemiology and global health, genes and chromosomes, genomics and evolutionary biology, human biology and medicine, immunology, microbiology and infectious disease, neuroscience, and plant biology. It also offers podcasts and tools and resources. eLife Sciences was launched in 2011 and its operations are based in Cambridge, United Kingdom. It is a joint initiative of the [Howard Hughes Medical Institute](https://www.crunchbase.com/organization/howard-hughes-medical-institute), the [Max Planck Society](https://www.crunchbase.com/organization/max-planck-society), and the [Wellcome Trust](https://www.crunchbase.com/organization/wellcome-trust).
Total amount:347
National Rank
(United Kingdom)
3rd
newRegional Rank
(Western Europe)
15th
1
Global Rank
(WorldWide)
85th
22