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Top Startup Exits in San Diego for 2026

In San Diego, we rank 13 startup exits based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Startup exits in San Diego are falling behind the performance of their global counterparts.

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Top Startup Exits in San Diego for 2026

1st
Receptos logo
ReceptosSB Score: 537Public Exit

Receptos is a privately-held drug discovery and development company which utilizes pioneering G protein-coupled receptor (GPCR) technology to facilitate information-driven drug design for developing best- and first-in-class drugs.

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Website
www.bms.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$103.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Reneo Pharmaceuticals logo
Reneo PharmaceuticalsSB Score: 490Public Exit

Reneo Pharmaceuticals is an operator of a pharmaceutical company used to develop therapies for patients with orphan metabolic diseases. It focuses on the development of treatments for genetic disorders associated with defects in energy metabolism resulting in myopathy that enable caregivers to improve the daily function and quality of life of patients suffering from these diseases by improving how their mitochondria work, preserving muscle function and preventing muscle injury, weakness, and wasting. The company was founded in 2014 and is headquartered in San Diego, California.

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Website
reneopharma.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$145M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Vividion Therapeutics logo
Vividion TherapeuticsSB Score: 441Public Exit

Vividion is a biotechnology company focused on developing innovative therapeutics that treat major unmet clinical needs using the first platform for proteome-wide drug and target discovery.

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Website
www.vividion.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$371.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:9

Largest Startup Exits in San Diego by Funding

The top three largest startup exits in San Diego have raised total funding of more than USD 116M. Among the top three funded exits, the most popular industry, based on total funding, is Healthtech.
1st
Receptos logo
ReceptosSB Score: 537Public Exit

Receptos is a privately-held drug discovery and development company which utilizes pioneering G protein-coupled receptor (GPCR) technology to facilitate information-driven drug design for developing best- and first-in-class drugs.

View Full Page
Website
www.bms.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$103.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
BioLegend logo
BioLegendSB Score: 279Public Exit

BioLegend is a biotechnology firm that offers immunological reagents for biomedical research.

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Website
biolegend.com
Employee range
501 – 1,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:9

Top Hiring Startup Exits in San Diego by Employee Size

The top three hiring startup exits in San Diego have an average employee size that is smaller than to the global average. Among these, the Healthtech industry features the startup exit with the largest workforce.
1st
BioLegend logo
BioLegendSB Score: 279Public Exit

BioLegend is a biotechnology firm that offers immunological reagents for biomedical research.

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Website
biolegend.com
Employee range
501 – 1,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Vividion Therapeutics logo
Vividion TherapeuticsSB Score: 441Public Exit

Vividion is a biotechnology company focused on developing innovative therapeutics that treat major unmet clinical needs using the first platform for proteome-wide drug and target discovery.

View Full Page
Website
www.vividion.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$371.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Omniome logo
OmniomeSB Score: 376Public Exit

Omniome engages in developing a proprietary DNA sequencing platform capable of delivering unsurpassed sequencing accuracy.

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Website
www.omniome.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$126.6M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Receptos logo
ReceptosSB Score: 537Public Exit

Receptos is a privately-held drug discovery and development company which utilizes pioneering G protein-coupled receptor (GPCR) technology to facilitate information-driven drug design for developing best- and first-in-class drugs.

View Full Page
Website
www.bms.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$103.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:13

Explore More Top Startups

Explore the Startup Ecosystem of San Diego

National Rank

(United States)

10th

new

Regional Rank

(North America)

10th

1

Global Rank

(WorldWide)

23rd

1

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
2026 National Rank CityGlobal RankTotal Score & National ShareAnnual Growth

Access subscores for 1000 cities and 100 countries

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