34 Top startups in Winston-Salem for January 2025

We rank Javara Research, Triad Semiconductor and Fluree in Winston-Salem along with 31 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Winston-Salem ranks #387 globally and #113 in United States.

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Best Startups in Winston-Salem for 2025

SB Score:421

Javara is an innovative Integrated Research Organization (IRO) revolutionizing the clinical research process. They aim to enhance the experience for all involved by providing comprehensive services and solutions.

Industry:
Healthtech
Subindustry:
Health-Other

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SB Score:394

Triad Semiconductor specializes in developing customizable analog and digital technology for mixed-signal ASICs. They create prototypes for various applications in the market, offering innovative solutions to meet unique design needs.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:363

Fluree leverages decentralized apps and a blockchain database for streamlined, secure data management. Their innovative platform offers a seamless user experience, empowering businesses to harness the power of blockchain technology for improved efficiency and transparency.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:352

Titan's Next Generation Mining Pool provides North American Bitcoin miners with a powerful alternative for achieving efficiency and scale. Offering both public and private mining pool services, Titan ensures a competitive edge in the market.

Industry:
Software & Data
Subindustry:
Software

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SB Score:344

F5 Sports utilizes body movement data to enhance player performance through real-time insights. Their pitchLogic ball and mobile apps aid players in training efficiently and achieving success in games of all levels.

Industry:
Social & Leisure
Subindustry:
Sports

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SB Score:324

Introducing a revolutionary closed-loop fashion economy solution. This startup enables users to easily recycle and upcycle clothing items, promoting sustainable practices in the fashion industry. Join the movement towards a more environmentally friendly future.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:320

Precise Bio is a regenerative medicine company based in Winston-Salem, North Carolina, specializing in the development and commercialization of 4D bio-fabricated functional tissues and organs, aiming to revolutionize healthcare by providing innovative solutions for tissue and organ replacement.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:307

Wellnecity revolutionizes healthcare interactions for employers and employees through innovative technology solutions. Their platform streamlines access to healthcare services, creating a seamless experience for all users.

Industry:
Healthtech
Subindustry:
Health Care

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10th

Vispa
SB Score:277

Vispa offers a collaborative team of experienced process management experts, technologists, and business leaders dedicated to simplifying the complex revenue cycle management process for healthcare organizations. Their mission is to enhance efficiency and effectiveness, ensuring that healthcare providers can focus on what matters most: patient care.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:276

This startup addresses the frequent interruptions in high-end production caused by equipment failures. By leveraging innovative technology, it enhances reliability and performance of essential gear, ensuring smooth operations on set and reducing downtime during live broadcasts or film shoots.

Industry:
Social & Leisure
Subindustry:
Entertainment

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Total amount:34

Top 14 Healthtech Startups in Winston-Salem for 2025

The top three Healthtech startups in Winston-Salem have raised more than USD 81.4M. Winston-Salem ranks #184 globally for the Healthtech industry.
SB Score:421

Javara is an innovative Integrated Research Organization (IRO) revolutionizing the clinical research process. They aim to enhance the experience for all involved by providing comprehensive services and solutions.

Industry:
Healthtech
Subindustry:
Health-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:320

Precise Bio is a regenerative medicine company based in Winston-Salem, North Carolina, specializing in the development and commercialization of 4D bio-fabricated functional tissues and organs, aiming to revolutionize healthcare by providing innovative solutions for tissue and organ replacement.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

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SB Score:307

Wellnecity revolutionizes healthcare interactions for employers and employees through innovative technology solutions. Their platform streamlines access to healthcare services, creating a seamless experience for all users.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

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Total amount:14

Top 9 Software & Data Startups in Winston-Salem for 2025

The top three Software & Data startups in Winston-Salem have raised more than USD 36.9M. Winston-Salem ranks #447 globally for the Software & Data industry.
SB Score:363

Fluree leverages decentralized apps and a blockchain database for streamlined, secure data management. Their innovative platform offers a seamless user experience, empowering businesses to harness the power of blockchain technology for improved efficiency and transparency.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

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Regional Rank (North America)

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SB Score:352

Titan's Next Generation Mining Pool provides North American Bitcoin miners with a powerful alternative for achieving efficiency and scale. Offering both public and private mining pool services, Titan ensures a competitive edge in the market.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

0

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SB Score:223

SWIPEBY empowers suburban restaurants with automated curbside service to boost sales and loyalty.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Total amount:9

Top 4 Ecommerce & Retail Startups in Winston-Salem for 2025

The top three Ecommerce & Retail startups in Winston-Salem have raised more than USD 1.11M. Winston-Salem ranks #283 globally for the Ecommerce & Retail industry.
SB Score:324

Introducing a revolutionary closed-loop fashion economy solution. This startup enables users to easily recycle and upcycle clothing items, promoting sustainable practices in the fashion industry. Join the movement towards a more environmentally friendly future.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

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Regional Rank (North America)

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SB Score:119

Rent Assured is an award-winning company revolutionizing the rental industry with cutting-edge PropTech. Their innovative solution digitizes workflows, enhances transparency, and benefits all involved in the tenancy process.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

National Rank (United States)

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SB Score:107

Jenni Earle is an online marketplace for stylish clothing and fashion accessories, founded in 2022 and based in Winston-Salem, North Carolina. With a focus on quality and trendiness, it connects fashion enthusiasts with unique pieces that elevate their wardrobe and express their personal style.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

National Rank (United States)

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Total amount:4

Most Funded Startups in Winston-Salem for 2025

The top three most funded startups in Winston-Salem have raised total funding of more than USD 121M. Javara Research has 1.12% more funding than Triad Semiconductor.
SB Score:421

Javara is an innovative Integrated Research Organization (IRO) revolutionizing the clinical research process. They aim to enhance the experience for all involved by providing comprehensive services and solutions.

Industry:
Healthtech
Subindustry:
Health-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:394

Triad Semiconductor specializes in developing customizable analog and digital technology for mixed-signal ASICs. They create prototypes for various applications in the market, offering innovative solutions to meet unique design needs.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:363

Fluree leverages decentralized apps and a blockchain database for streamlined, secure data management. Their innovative platform offers a seamless user experience, empowering businesses to harness the power of blockchain technology for improved efficiency and transparency.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:34

Top Hiring Startups in Winston-Salem by Employee Number

The top three hiring startups in Winston-Salem have an median employee size that is between [101-250]
SB Score:421

Javara is an innovative Integrated Research Organization (IRO) revolutionizing the clinical research process. They aim to enhance the experience for all involved by providing comprehensive services and solutions.

Industry:
Healthtech
Subindustry:
Health-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:394

Triad Semiconductor specializes in developing customizable analog and digital technology for mixed-signal ASICs. They create prototypes for various applications in the market, offering innovative solutions to meet unique design needs.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:363

Fluree leverages decentralized apps and a blockchain database for streamlined, secure data management. Their innovative platform offers a seamless user experience, empowering businesses to harness the power of blockchain technology for improved efficiency and transparency.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:352

Titan's Next Generation Mining Pool provides North American Bitcoin miners with a powerful alternative for achieving efficiency and scale. Offering both public and private mining pool services, Titan ensures a competitive edge in the market.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:34

Explore the Startup Ecosystem of Winston-Salem

National Rank

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113th

1

Regional Rank

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127th

0

Global Rank

(WorldWide)

387th

20

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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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121.937
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109.679
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