Top startups in St. Louis for 2024

In St. Louis, we rank 210 startups based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Startups in St. Louis are exceeding the performance of their global counterparts.

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Best Startups in St. Louis for 2024

SB Score:513

Specializing in commercial real estate and online marketplace, this innovative Real Estate company offers a seamless platform for buyers and sellers. With a focus on efficiency and expertise, they provide a one-stop solution for all your commercial property needs.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:506

Lumeris is an accountable care delivery innovation company

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:493

Adalo is a tech company focused on Android, software, and IT. Specializing in creating innovative solutions, they offer cutting-edge products for businesses and individuals. With a passion for technology, Adalo strives to make complex systems accessible and user-friendly for all.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

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Regional Rank (North America)

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SB Score:471

Playbite is a social gaming platform where users can socialize, play, earn, and compete. Playbite was founded by Diego Kafie, Stu Feldt, and Nic Weber.

Industry:
Edtech
Subindustry:
Edtech

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:462

Surround Care focuses on fixing healthcare affordability, quality, access, and experience for all.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

0

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SB Score:451

Travel in style and comfort with wardrobe essentials that are perfect for both the journey and the destination. Our collection of clothing and accessories ensures you look and feel your best no matter where you go.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:427

Revolutionize HR with a cutting-edge SaaS platform for performance management, learning, and rewards. Drive engagement and boost productivity with our innovative technology, designed to optimize employee performance.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:427

PierianDx is driving worldwide integration of genomic sequencing in healthcare, revolutionizing personalized medicine.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:427

Balto enhances contact center performance by providing real-time guidance to boost conversions, improve customer experience, and reduce ramp time.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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10th

Textel
SB Score:425

Textel provides businesses with technology to text customers using their existing phone numbers. Engage with customers easily and efficiently through business texting.

Industry:
Software & Data
Subindustry:
Comtech

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:420

Geneoscopy is revolutionizing colorectal cancer screening with a noninvasive stool sample test. Our innovative biomarker technology detects cancer early, making diagnosis easier and more accessible. Join us in the fight against colorectal cancer.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:211

Most Funded Startups in St. Louis for 2024

The top three most funded startups in St. Louis have raised total funding of more than USD 997M. Among the top three funded startups, the most popular industry, based on total funding, is Healthtech.

SB Score:462

Surround Care focuses on fixing healthcare affordability, quality, access, and experience for all.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:506

Lumeris is an accountable care delivery innovation company

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:393

Wugen is developing off-the-shelf cellular therapies targeting solid tumors and hematologic malignancies

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:211

Top Hiring Startups in St. Louis by Employee Number

The top three hiring startups in St. Louis have an average employee size that is smaller than to the global average. Among these, the Healthtech industry features the startup with the largest workforce.

SB Score:506

Lumeris is an accountable care delivery innovation company

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:462

Surround Care focuses on fixing healthcare affordability, quality, access, and experience for all.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:332

Hicuity Health is a technology-enabled clinical services provider and the nation’s leading provider of high acuity telehealth services.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:210

Explore the Startup Ecosystem of St. Louis

National Rank

(United States)

40th

3

Regional Rank

(North America)

46th

3

Global Rank

(WorldWide)

115th

3

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Best Healthtech Startups in St. Louis for 2024

St. Louis startups in the Healthtech industry are overperforming their global industry peers. The top three Healthtech startups in St. Louis have raised more than USD 997M, an amount that is higher than the global industry average.

SB Score:506

Lumeris is an accountable care delivery innovation company

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:462

Surround Care focuses on fixing healthcare affordability, quality, access, and experience for all.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:427

PierianDx is driving worldwide integration of genomic sequencing in healthcare, revolutionizing personalized medicine.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse

Total amount:38

Best Software & Data Startups in St. Louis for 2024

St. Louis startups in the Software & Data industry are overperforming their global industry peers. The top three Software & Data startups in St. Louis have raised more than USD 160M, an amount that is higher than the global industry average.

SB Score:493

Adalo is a tech company focused on Android, software, and IT. Specializing in creating innovative solutions, they offer cutting-edge products for businesses and individuals. With a passion for technology, Adalo strives to make complex systems accessible and user-friendly for all.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:427

Revolutionize HR with a cutting-edge SaaS platform for performance management, learning, and rewards. Drive engagement and boost productivity with our innovative technology, designed to optimize employee performance.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:427

Balto enhances contact center performance by providing real-time guidance to boost conversions, improve customer experience, and reduce ramp time.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse

Total amount:52

Best Ecommerce & Retail Startups in St. Louis for 2024

St. Louis startups in the Ecommerce & Retail industry are overperforming their global industry peers. The top three Ecommerce & Retail startups in St. Louis have raised more than USD 43.6M, an amount that is higher than the global industry average.

SB Score:513

Specializing in commercial real estate and online marketplace, this innovative Real Estate company offers a seamless platform for buyers and sellers. With a focus on efficiency and expertise, they provide a one-stop solution for all your commercial property needs.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:451

Travel in style and comfort with wardrobe essentials that are perfect for both the journey and the destination. Our collection of clothing and accessories ensures you look and feel your best no matter where you go.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
SB Score:406

Customily is an e-commerce platform that allows customers to personalize products online.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse

Total amount:22

Top Cities for Startups in United States - Ranked by StartupBlink
StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
1st
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1st
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710.966
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2nd
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251.377
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3rd
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4th
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121.937
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4th
0
5th
0
109.679
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