StartupBlink

29 Top startups in South Bend for September 2026

We rank TayCo Brace, Trek10 and Emu Technology in South Bend along with 26 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. South Bend startup ecosystem ranks #611 globally and #157 in United States.

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Best Startups in South Bend for 2026

1st
TayCo Brace logo
TayCo BraceSB Score: 321

TayCo Brace is a medical device company that manufactures a custom-fit external ankle brace. The TayCo Brace offers immediate functional recovery for driving, work, and sports. It is custom fit for enhanced stability, performance, and comfort.

View Full Page
Website
taycobrace.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$792K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Trek10 logo
Trek10SB Score: 304

Trek10 is passionate about Amazon Web Services and the benefits of public cloud computing. We have years of experience on Amazon Web Services, and were founded in 2013 after repeated experiences with clients made it clear just how many businesses could greatly benefit from the power of AWS, through increased efficiency, greater flexibility, and reduced cost. Trek10 designs, builds, and supports cutting-edge solutions for our clients using the absolute best tools and AWS platform services. With multiple production deployments under our belt, our team is one of the foremost experts on building serverless apps and enabling enterprises to migrate to serverless architectures. Massive scalability, heavy automation, and remarkably low operating costs are our hallmarks.

View Full Page
Website
www.trek10.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$900K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
OpStart logo
OpStartSB Score: 274

OpStart is a management consulting company that offers bookkeeping, tax, back office setups, fractional CFO, and administrative support.

View Full Page
Website
www.opstart.co
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$1.3M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
SAFA logo
SAFASB Score: 235

SAFA was built to reduce the cost and effort associated with evolving and reusing safety cases while maintaining safety.

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Website
safa.ai
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$775K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
5th
Vital View Technologies logo

PrīmSphera (fka Vital View Technologies) is a revolutionary sensor technology company pioneering break-through solutions to solve real-world challenges. Our vision is to create a contactless sensor platform to improve effective decision making by unlocking insights that are otherwise unavailable. With applications in defense, and food processing, PrīmSphera has selected Healthcare as a primary industry for the beachhead market. Founded as a catalyst to commercialize the research of Dr. Thomas Pratt at The University of Notre Dame, who is a pioneer in leveraging radio frequency polarization mode dispersion (RF-PMD) for a range of sensing applications. The name ‘PrīmSphera’ (Pryme-SFair-uh) embodies our mission to deliver pioneering solutions (‘Prīm’—meaning first) and highlights the unique spherical output of Dr. Thomas Pratt’s groundbreaking work. Today, PrīmSphera are actively developing its flagship product, a state-of-the-art connected solution for the hospital-at-home. This monitoring platform features a proprietary non-contact, at-home medical monitor that tracks fluid change over time. This provides early, actionable data to patients and clinicians to inform care plans.

View Full Page
Website
vitalviewtech.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$5.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
6th
ProMazo logo
ProMazoSB Score: 219

ProMazo is a software company that designs and develops workforce HR solutions to helps companies.

View Full Page
Website
promazo.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$125K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
7th
Cobomba logo
CobombaSB Score: 218

Cobomba is an AI marketing planning platform designed to help content marketers plan content that works. Marketers spend too much time on research and strategy and still end up guessing about the marketing content they create. It provides intelligent content software to help 1000s of marketers know what marketing content to create because businesses flounder when marketers are uncertain about the content to create and don’t have the time to create it. The company was founded in 2020 and is headquartered in South Bend, Indiana.

View Full Page
Website
www.cobomba.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$1.6M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
8th
NearWave logo
NearWaveSB Score: 201

NearWave is involved in developing a device poised to democratize point-of-care diagnostics and imaging in breast cancer. The application allows for real-time visual display of 1D, 2D, and 3D quantitative imaging data.

View Full Page
Website
nearwave.co
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$500K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
9th
Crossroads Solar logo
Crossroads SolarSB Score: 185

Boston Microtechnology is a semiconductor company that specializes in the development of CMOS-integrated isolated AC/DC conversion. The company was founded in 2014 and is based in Burlington, Massachusetts.

View Full Page
Website
www.crossroads-solar.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$224.6K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
10th
Rides2U logo
Rides2USB Score: 176

Rides2U is a rideshare company that offers transparent price rides. The company was founded in 2021 by Chad Mastagh and is headquartered in South Bend, Indiana, United States.

View Full Page
Website
rides2u.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$80K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
11th
Orthos logo
OrthosSB Score: 91

Orthos helps orthopaedic providers and patients keep their focus on care by ensuring their business operations and revenue cycle perform. Orthos is a business intelligence solution for orthopedic practices.

View Full Page
Website
www.orthosinc.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:13

Most Funded Startups in South Bend for 2026

The top three most funded startups in South Bend have raised total funding of more than USD 43M. Emu Technology has 2.52% more funding than Vennli.
1st
Vital View Technologies logo

PrīmSphera (fka Vital View Technologies) is a revolutionary sensor technology company pioneering break-through solutions to solve real-world challenges. Our vision is to create a contactless sensor platform to improve effective decision making by unlocking insights that are otherwise unavailable. With applications in defense, and food processing, PrīmSphera has selected Healthcare as a primary industry for the beachhead market. Founded as a catalyst to commercialize the research of Dr. Thomas Pratt at The University of Notre Dame, who is a pioneer in leveraging radio frequency polarization mode dispersion (RF-PMD) for a range of sensing applications. The name ‘PrīmSphera’ (Pryme-SFair-uh) embodies our mission to deliver pioneering solutions (‘Prīm’—meaning first) and highlights the unique spherical output of Dr. Thomas Pratt’s groundbreaking work. Today, PrīmSphera are actively developing its flagship product, a state-of-the-art connected solution for the hospital-at-home. This monitoring platform features a proprietary non-contact, at-home medical monitor that tracks fluid change over time. This provides early, actionable data to patients and clinicians to inform care plans.

View Full Page
Website
vitalviewtech.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$5.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Cobomba logo
CobombaSB Score: 218

Cobomba is an AI marketing planning platform designed to help content marketers plan content that works. Marketers spend too much time on research and strategy and still end up guessing about the marketing content they create. It provides intelligent content software to help 1000s of marketers know what marketing content to create because businesses flounder when marketers are uncertain about the content to create and don’t have the time to create it. The company was founded in 2020 and is headquartered in South Bend, Indiana.

View Full Page
Website
www.cobomba.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$1.6M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
OpStart logo
OpStartSB Score: 274

OpStart is a management consulting company that offers bookkeeping, tax, back office setups, fractional CFO, and administrative support.

View Full Page
Website
www.opstart.co
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$1.3M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:13

Top Hiring Startups in South Bend by Employee Number

The top three hiring startups in South Bend have an median employee size that is between [101-250]
2nd
ProMazo logo
ProMazoSB Score: 219

ProMazo is a software company that designs and develops workforce HR solutions to helps companies.

View Full Page
Website
promazo.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$125K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Trek10 logo
Trek10SB Score: 304

Trek10 is passionate about Amazon Web Services and the benefits of public cloud computing. We have years of experience on Amazon Web Services, and were founded in 2013 after repeated experiences with clients made it clear just how many businesses could greatly benefit from the power of AWS, through increased efficiency, greater flexibility, and reduced cost. Trek10 designs, builds, and supports cutting-edge solutions for our clients using the absolute best tools and AWS platform services. With multiple production deployments under our belt, our team is one of the foremost experts on building serverless apps and enabling enterprises to migrate to serverless architectures. Massive scalability, heavy automation, and remarkably low operating costs are our hallmarks.

View Full Page
Website
www.trek10.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$900K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
TayCo Brace logo
TayCo BraceSB Score: 321

TayCo Brace is a medical device company that manufactures a custom-fit external ankle brace. The TayCo Brace offers immediate functional recovery for driving, work, and sports. It is custom fit for enhanced stability, performance, and comfort.

View Full Page
Website
taycobrace.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$792K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:29

Explore More Top Startups

Explore the Startup Ecosystem of South Bend

National Rank

(United States)

157th

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Regional Rank

(North America)

186th

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Global Rank

(WorldWide)

611th

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
2026 National Rank CityGlobal RankTotal Score & National ShareAnnual Growth

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