StartupBlink

422 Top startups in San Mateo for July 2026

We rank GoPro, Alpaca and Yellow.ai in San Mateo along with 419 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Mateo is part of San Francisco Bay startup ecosystem which ranks #1 globally and #1 in North America.

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Top Unicorn Startups in San Mateo for 2026

Nine startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in San Mateo have raised more than USD 13.7B.
1st
Verkada logo
VerkadaSB Score: 669

Verkada's user-friendly software platform, Command, simplifies camera and site management across all devices. Effortlessly monitor and control cameras with intuitive features for seamless operation.

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Website
www.verkada.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$663.9M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Evidation Health logo
Evidation HealthSB Score: 604

Evidation measures health in everyday life and enables anyone to participate in groundbreaking research and health programs. Built upon a foundation of user privacy and control over permissioned health data, Evidation's Achievement platform is trusted by millions of individuals—generating data with unprecedented speed, scale, and rigor. We partner with leading healthcare companies to understand health and disease outside the clinic walls. Guided by our mission to enable and empower everyone to participate in better health outcomes, Evidation is working to bring people individualized, proactive, and accessible healthcare—faster. Founded in 2012, Evidation Heath is headquartered in California. We collaborate as a distributed team with additional offices around the globe. To learn more, visit evidation.com, or follow us on Twitter @evidation

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Website
www.evidation.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$259M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Neo4j logo
Neo4jSB Score: 595

Neo4j is the leading graph data platform, empowering organizations like Comcast, ICIJ, NASA, UBS, and Volvo Cars to harness real-world context in their data for solving challenges of all sizes.

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Website
neo4j.com
Employee range
501 – 1,000
Web Traffic (Monthly)
Funding amount
$581.1M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:9

Best Startups in San Mateo for 2026

1st
GoPro logo
GoProSB Score: 632

GoPro is an activity image capture company. It is a brand of personal cameras used in extreme action video photography. GoPro produces HD HERO, a line of wearable and gear-mountable cameras and accessories, making it easy for people to capture and share their lives' most exciting moments in high definition. GoPro's products are sold through specialty retailers in more than 50 countries and online. Founded in 2002 by Nicholas Woodman, GoPro is headquartered in San Mateo, California, United States.

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Website
gopro.com
Employee range
501 – 1,000
Web Traffic (Monthly)
Funding amount
$88.2M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Alpaca logo
AlpacaSB Score: 596

Alpaca is a developer-first embedded financial technologies platform that’s raised over $100m in funding. Alpaca offers crypto and stock investing, real-time market data, and end-to-end brokerage infrastructure through modern APIs. Alpaca supports hundreds of apps and businesses across the globe and is actively used by tens of thousands of enthusiastic developers. Alpaca is backed by top investors in the industry globally, including Portage Ventures, Spark Capital, Social Leverage, Tribe Capital, Horizons Ventures, Unbound, Eldridge, Positive Sum, Elefund, and Y Combinator.

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Website
alpaca.markets
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$288.8M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Yellow.ai logo
Yellow.aiSB Score: 562

Yellow.ai is an Agentic AI platform that sets the bar for intelligent service automation to deliver unmatched customer and employee experiences for enterprises. Headquartered in San Mateo, Yellow.ai serves over 1300+ enterprises, including Sony, Domino’s, Hyundai, Ferrellgas, Logitech, Waste Connections, Randstad, Tiket.com, Lulu Group International, Papa Johns, Volkswagen, and ITC Ltd., across 85+ countries in 135+ languages. The platform is built on a multi-LLM architecture and is continuously trained on 16B+ conversations annually, enabling businesses to deliver elevated experiences and build lasting customer relationships. Founded in 2016 with offices across six countries, Yellow.ai has raised over $102 million from blue-chip investors.

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Website
yellow.ai
Employee range
501 – 1,000
Web Traffic (Monthly)
Funding amount
$102.2M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Engageli logo
EngageliSB Score: 562

Engageli operates as an inclusive digital learning platform optimized for student success and that delivers engaging teaching and learning experiences across a broad spectrum of needs for higher education.

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Website
www.engageli.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$47.5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
5th
OneSignal logo
OneSignalSB Score: 558

OneSignal is a customer messaging and engagement platform that allows businesses to provide a seamless messaging experience to create meaningful customer connections. OneSignal's multi-channel platform enables businesses to deliver over 8 billion messages daily. OneSignal is designed to scale with businesses and deliver messages more quickly. The platform leverages machine learning to send communications at the optimal time by creating personalized messages and sending them to the right audiences by comparing performance, enabling clients to deliver engaging mobile and web push messages across all platforms.

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Website
onesignal.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$82M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
6th
Galxe logo
GalxeSB Score: 555

Galxe is the leading Web3 credential data network in the world. A collaborative credential infrastructure enabling brands and developers to engage communities and build robust products in Web3. (Previously known as Project Galaxy)

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Website
galxe.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$10M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
7th
Step logo
StepSB Score: 548

Step is a financial services company that builds mobile-based banking for teenagers. It helps teens and young adults achieve financial independence and knowledge at an earlier age. The company's mission is to create a bank that gives its users the tools to become smarter with their money and reward them along their financial journey. It was founded in 2018 and headquartered in Palo Alto, California.

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Website
step.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$176.3M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
8th
Helix logo
HelixSB Score: 548

Helix integrates genomics data into clinical care, advancing research and personalized health solutions.

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Website
www.helix.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$403M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
9th
Luminate Health logo
Luminate HealthSB Score: 539

A Cloud Guru leads the world in cloud computing training with Amazon, Google, and Azure. Their online platform offers courses to prepare engineers to take certification exams for the three major cloud providers. ACG enables professionals to learn on their time and at their own pace.

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Website
www.luminatehealth.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$40M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
10th
Reebelo Pte. Ltd. logo
Reebelo Pte. Ltd.SB Score: 537

Reebelo operates as an online marketplace specializing in refurbished and pre-owned electronics. The company offers a selection of certified devices, including smartphones, tablets, and laptops, aiming to provide alternatives to new products through a sustainable approach. Reebelo manages quality assurance processes to ensure device functionality and condition. The platform facilitates buying and selling while providing warranties and customer support related to its products. The company serves both individual consumers and businesses seeking refurbished technology solutions.

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Website
reebelo.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$50.3M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
11th
Workona logo
WorkonaSB Score: 533

Workona offers a cloud-based work management platform that enables users to access and manage resources. They offered features including workspace tabs, tab management, tab suspension, document templates, and more.

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Website
workona.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$6M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:284

Most Funded Startups in San Mateo for 2026

The top three most funded startups in San Mateo have raised total funding of more than USD 1.45B. Veev has 0.26% more funding than Observe.
1st
Veev logo
VeevSB Score: 458

Veev is a building technology company that reinvents the way homes are built and experienced. Veev's home operating system creates room-specific lighting, shade, and climate control and also offers protection against intrusion and cybercrime, thereby providing clients a one-stop solution to all their smart housing requirements. Key components of the Veev panelized building system include the use of light gauge steel (LGS) for framing, high-performance acrylic (HPA) for surfaces and millwork, radiant climate control systems, and a digital home ecosystem. The company is currently focused on high-performance multifamily and accessory dwelling unit (ADU) products. The current development pipeline totals more than 230 units and 620,000 gross building square feet.

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Website
www.veev.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$585M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Observe logo
ObserveSB Score: 485

Observe is an observability platform built on a streaming data lake for faster search and correlation at a lower cost. The company uses an O11y Knowledge Graph to structure logs, metrics, and traces as entities with semantic relationships. It also uses O11y AI to help resolve incidents faster and reduce costs.

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Website
www.observeinc.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$463M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Helix logo
HelixSB Score: 548

Helix integrates genomics data into clinical care, advancing research and personalized health solutions.

View Full Page
Website
www.helix.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$403M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:284

Top Hiring Startups in San Mateo by Employee Number

The top three hiring startups in San Mateo have an median employee size that is between [1001-5000]
1st
Momentive logo
MomentiveSB Score: 362

Momentive Performance Materials specializes in silicones and advanced materials, with a 75+ year heritage of being first to market with performance applications for major industries that support and improve everyday life. The Company delivers science-based solutions, by linking custom technology platforms to opportunities for customers. Momentive Specialty Chemicals Inc. is now Hexion Inc., the global leader in thermoset resins. Hexion serves the global wood and industrial markets through a broad range of thermoset technologies, specialty products, and technical support for customers in a diverse range of applications and industries.

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Website
www.momentive.ai
Employee range
5,001 – 10,000
Web Traffic (Monthly)
Funding amount
$804.9K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Apttus logo
ApttusSB Score: 455

Apttus is a SaaS application provider that renders enterprise-class applications for end-to-end management of business functions. Its enterprise-class software drives the vital business process between the buyer’s interest in a purchase and the realization of revenue. Delivered on a comprehensive cloud platform, the Salesforce Platform, Apttus’ Quote-to-Cash solutions increase sales and maximize visibility and control. Applications include Configure-Price-Quote (CPQ), contract management, renewals, and revenue management. Additionally, Apttus’ patent-pending X-Author technology enables Microsoft Office to be a user interface with full interaction and control between Salesforce and Microsoft Office.

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Website
apttus.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$329M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
PingPong logo
PingPongSB Score: 405

Revolutionizing global eCommerce, this unique Fintech startup is dedicated to empowering marketplace sellers worldwide. Their focus on international markets sets them apart, making them the go-to choice for sellers looking to streamline their financial transactions and grow their businesses on a global scale.

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Website
usa.pingpongx.com/us/index
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
$122M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Composite Software logo
Composite SoftwareSB Score: 293

TIBCO unlocks the potential of real-time data for making faster, smarter decisions. Our Connected Intelligence platform seamlessly connects any application or data source; intelligently unifies data for greater access, trust, and control; and confidently predicts outcomes in real time and at scale. Thousands of customers around the globe rely on TIBCO to build compelling experiences, energize operations, and propel innovation.

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Website
www.tibco.com/products/tibco-data-virtualization
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:422

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
2026 National Rank CityGlobal RankTotal Score & National ShareAnnual Growth

Access subscores for 1000 cities and 100 countries

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