StartupBlink

51 Top startups in San Luis Obispo for July 2026

We rank Postal, Hello Work and Pashion Footwear in San Luis Obispo along with 48 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Luis Obispo startup ecosystem ranks #437 globally and #118 in United States.

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Best Startups in San Luis Obispo for 2026

SB Score:463

Postal is the leading intelligent gifting platform that helps thousands of businesses increase their pipeline, retain customers, and reward employees. The platform and its global marketplace enable customers to automate direct mail, manage branded company swag, and send personalized gifts, all while centralizing cost and reducing waste. Postal is the everything app for gifting, integrating seamlessly with your favorite workplace tools including Salesforce, Microsoft, Google, Hubspot, and Workday. This allows you to automate and track sends and spending effortlessly. At Postal, we believe in maintaining a strong work/life/spiritual balance, which is fostered by a robust company culture focused on making the world a better place. We embrace people for who they are and believe that diversity, inclusion, and belonging are our greatest strengths. Postal has raised over $30 million in two funding rounds from top-tier investors such as Mayfield Fund (Marketo, Outreach) and OMERS Capital (Shopify, Crunchbase).

Industry:
Software & Data
Subindustry:
Software

City Rank (San Luis Obispo)

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SB Score:409

HelloWork is online employment, recruitment, and training service that assists workers and students throughout their professional life, as well as companies, recruitment agencies and temporary employment agencies with hr and recruitment matters, and helps training centres and schools make their offers.

Industry:
Social & Leisure
Subindustry:
Arts

City Rank (San Luis Obispo)

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SB Score:395

Pashion has completely "reinvented the heel" through the creation of the world's first fully convertible heel-to-flat technology. Combining excellent technical execution with classic styles, their disruptive two-shoes-in-one design is the up-and-coming solution to the pain, injury, and inconvenience associated with wearing high heels. The company has sourced a supply chain and production process that is completely unique to the high heel space, and their innovative design is patent-pending in 30 countries. In addition to heel-to-flat capability, Pashion shoes boast incredible comfort ratings due to their unique material profile. The brand has also recently brought to market an interchangeable heel kit design, allowing for multiple aesthetic looks to appear on one shoe. Pashion is building a lifestyle brand focused on empowering women in their daily lives. The woman of today deserves a shoe that can keep up with her - no matter where she’s headed. Pashion has raised a total of $3.17M in angel & venture funding.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

City Rank (San Luis Obispo)

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SB Score:395

Flume is dedicated to conserving water and safeguarding homes by providing homeowners and communities with real-time water usage data. Founded in 2016 and based in San Luis Obispo, California, Flume empowers users to monitor their water consumption, helping to eliminate waste and promote sustainable practices.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

City Rank (San Luis Obispo)

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WhiteFox Defense Technologies develops and provides drone threat mitigation device the DroneFox. It offers two systems DroneFox Tactical, a portal mobile device which responds to drone threats based on operator feedback or automatically based on preset conditions; DroneFox Fortify, a fixed device which integrates and provides continues automatic protection of vulnerable facilities and critical infrastructure. WhiteFox Defense's device detects small and modified drones in airspace, analyses target drones based on variables including its model, location, and flight pattern, and reroutes. Additionally, its clientele include critical infrastructure protection, homeland security, public safety, and defense. Luke Fox founded WhiteFox Defense in 2016. It has its headquarters in San Luis Obispo in California.

Industry:
Hardware & IoT
Subindustry:
Robotics

City Rank (San Luis Obispo)

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SB Score:349

DonateStock is a B2B fintech software company unlocking a $100 billion market by making charitable stock gifting accessible and easy for millions of nonprofits and investors. Our API-driven Easy Button enables investors to donate stock with ease while enabling all nonprofits to receive stock gifts with transparency and automation. As the de facto leader in charitable stock gifting, we offer the first and only end-to-end stock gifting solution for donors, advisors and nonprofits. Our plug-in is the first to be distributed by online donation platforms to offer stock gifting as a turnkey solution to tens of thousands of nonprofits.

Industry:
Software & Data
Subindustry:
Apps

City Rank (San Luis Obispo)

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SB Score:344

Rx Redefined empowers physicians to provide specialized medical products to patients through a seamless logistics platform. Founded in 2018 by Brandon Boots and Erik Smith, the Oakland-based company offers innovative healthcare solutions.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (San Luis Obispo)

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SB Score:337

King Energy is an innovative energy company that brings solar power solutions to multi-tenant commercial properties. By leasing unused roof space from property owners, King Energy manages the financing, installation, and long-term maintenance of solar infrastructure, simplifying the transition to renewable energy for all stakeholders involved.

Industry:
Energy & Environment
Subindustry:
Energy

City Rank (San Luis Obispo)

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SB Score:319

Tastry is a sensory sciences company that combines analytical chemistry, consumer flavor preferences and machine learning to predict market performance for sensory-based products. Tastry’s patented method provides consumer recommendations with incredible accuracy.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

City Rank (San Luis Obispo)

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SB Score:301

FarmBot is an open-source CNC farming machine and software package designed for small-scale precision food production. Similar to 3D printers and CNC milling machines, FarmBot hardware employs linear guides in the X, Y, and Z directions. This allows for tooling such as seed injectors, watering nozzles, sensors, and weed removal tools to be precisely positioned and used on the plants and soil. FarmBot is controlled by an Arduino/RAMPS stack and an internet connected Raspberry Pi 2. The hardware is designed to be simple, scalable, hackable, and easily produced.

Industry:
Foodtech
Subindustry:
Agtech

City Rank (San Luis Obispo)

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SB Score:298

StudentRoomStay (SRS) is on a mission to empower hosted accommodation and cross cultural connection for international students and fellows globally.

Industry:
Edtech
Subindustry:
Education-Other

City Rank (San Luis Obispo)

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Total amount:51

Top 7 Ecommerce & Retail Startups in San Luis Obispo for 2026

The top three Ecommerce & Retail startups in San Luis Obispo have raised more than USD 9.58M. San Luis Obispo startup ecosystem ranks #329 globally for the Ecommerce & Retail industry.
SB Score:395

Pashion has completely "reinvented the heel" through the creation of the world's first fully convertible heel-to-flat technology. Combining excellent technical execution with classic styles, their disruptive two-shoes-in-one design is the up-and-coming solution to the pain, injury, and inconvenience associated with wearing high heels. The company has sourced a supply chain and production process that is completely unique to the high heel space, and their innovative design is patent-pending in 30 countries. In addition to heel-to-flat capability, Pashion shoes boast incredible comfort ratings due to their unique material profile. The brand has also recently brought to market an interchangeable heel kit design, allowing for multiple aesthetic looks to appear on one shoe. Pashion is building a lifestyle brand focused on empowering women in their daily lives. The woman of today deserves a shoe that can keep up with her - no matter where she’s headed. Pashion has raised a total of $3.17M in angel & venture funding.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

City Rank (San Luis Obispo)

0

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Regional Rank (North America)

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SB Score:225

Moja Gear builds immersive online retail experiences for outdoor enthusiasts. Its first venture, Moja Gear, serves as a central platform for rock climbing content, community, and gear. Moja Outdoors was founded in September 2014 and is based in San Luis Obispo, California, United States.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

City Rank (San Luis Obispo)

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Regional Rank (North America)

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Total amount:7

Top 6 Healthtech Startups in San Luis Obispo for 2026

The top three Healthtech startups in San Luis Obispo have raised more than USD 82.1M. San Luis Obispo startup ecosystem ranks #337 globally for the Healthtech industry.
SB Score:344

Rx Redefined empowers physicians to provide specialized medical products to patients through a seamless logistics platform. Founded in 2018 by Brandon Boots and Erik Smith, the Oakland-based company offers innovative healthcare solutions.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (San Luis Obispo)

0

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Regional Rank (North America)

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SB Score:283

Off Day Trainer is a text messaging program designed with coaches in mind. It scales businesses and clients outside of sessions, personalizes, and automates client communication. To assist people to build and manage the 30-day challenge, people may receive a resource library and training sessions.

Industry:
Healthtech
Subindustry:
Fitness

City Rank (San Luis Obispo)

0

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Regional Rank (North America)

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SB Score:268

Novocuff is a medical device firm that aims to improve pregnancy outcomes and reduce preterm deliveries caused by PPROM and cervical shortening.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (San Luis Obispo)

0

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Regional Rank (North America)

0

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0

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Total amount:6

Top 7 Hardware & IoT Startups in San Luis Obispo for 2026

The top three Hardware & IoT startups in San Luis Obispo have raised more than USD 35.8M. San Luis Obispo startup ecosystem ranks #357 globally for the Hardware & IoT industry.
SB Score:395

Flume is dedicated to conserving water and safeguarding homes by providing homeowners and communities with real-time water usage data. Founded in 2016 and based in San Luis Obispo, California, Flume empowers users to monitor their water consumption, helping to eliminate waste and promote sustainable practices.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

City Rank (San Luis Obispo)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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WhiteFox Defense Technologies develops and provides drone threat mitigation device the DroneFox. It offers two systems DroneFox Tactical, a portal mobile device which responds to drone threats based on operator feedback or automatically based on preset conditions; DroneFox Fortify, a fixed device which integrates and provides continues automatic protection of vulnerable facilities and critical infrastructure. WhiteFox Defense's device detects small and modified drones in airspace, analyses target drones based on variables including its model, location, and flight pattern, and reroutes. Additionally, its clientele include critical infrastructure protection, homeland security, public safety, and defense. Luke Fox founded WhiteFox Defense in 2016. It has its headquarters in San Luis Obispo in California.

Industry:
Hardware & IoT
Subindustry:
Robotics

City Rank (San Luis Obispo)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:298

Fracsun offers complete PV soiling monitoring solutions for solar array owners, operators, and developers. Fracsun specializes in measuring on-site soiling loss with its patented ARES soiling management system. It eliminates uncertainty by directly measuring soiling with local instrumentation, allowing teams to confidently monitor and manage the soiling loss. Fracsun's soiling dataset eliminates the guesswork in project development, lowering financial risk. Fracsun's mission is to improve the performance of solar assets.

Industry:
Hardware & IoT
Subindustry:
Hardware

City Rank (San Luis Obispo)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:7

Most Funded Startups in San Luis Obispo for 2026

The top three most funded startups in San Luis Obispo have raised total funding of more than USD 109M. Rx Redefined has 0.61% more funding than Postal.
SB Score:344

Rx Redefined empowers physicians to provide specialized medical products to patients through a seamless logistics platform. Founded in 2018 by Brandon Boots and Erik Smith, the Oakland-based company offers innovative healthcare solutions.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (San Luis Obispo)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:463

Postal is the leading intelligent gifting platform that helps thousands of businesses increase their pipeline, retain customers, and reward employees. The platform and its global marketplace enable customers to automate direct mail, manage branded company swag, and send personalized gifts, all while centralizing cost and reducing waste. Postal is the everything app for gifting, integrating seamlessly with your favorite workplace tools including Salesforce, Microsoft, Google, Hubspot, and Workday. This allows you to automate and track sends and spending effortlessly. At Postal, we believe in maintaining a strong work/life/spiritual balance, which is fostered by a robust company culture focused on making the world a better place. We embrace people for who they are and believe that diversity, inclusion, and belonging are our greatest strengths. Postal has raised over $30 million in two funding rounds from top-tier investors such as Mayfield Fund (Marketo, Outreach) and OMERS Capital (Shopify, Crunchbase).

Industry:
Software & Data
Subindustry:
Software

City Rank (San Luis Obispo)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:268

Novocuff is a medical device firm that aims to improve pregnancy outcomes and reduce preterm deliveries caused by PPROM and cervical shortening.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (San Luis Obispo)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:51

Top Hiring Startups in San Luis Obispo by Employee Number

The top three hiring startups in San Luis Obispo have an median employee size that is between [101-250]
SB Score:409

HelloWork is online employment, recruitment, and training service that assists workers and students throughout their professional life, as well as companies, recruitment agencies and temporary employment agencies with hr and recruitment matters, and helps training centres and schools make their offers.

Industry:
Social & Leisure
Subindustry:
Arts

City Rank (San Luis Obispo)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:463

Postal is the leading intelligent gifting platform that helps thousands of businesses increase their pipeline, retain customers, and reward employees. The platform and its global marketplace enable customers to automate direct mail, manage branded company swag, and send personalized gifts, all while centralizing cost and reducing waste. Postal is the everything app for gifting, integrating seamlessly with your favorite workplace tools including Salesforce, Microsoft, Google, Hubspot, and Workday. This allows you to automate and track sends and spending effortlessly. At Postal, we believe in maintaining a strong work/life/spiritual balance, which is fostered by a robust company culture focused on making the world a better place. We embrace people for who they are and believe that diversity, inclusion, and belonging are our greatest strengths. Postal has raised over $30 million in two funding rounds from top-tier investors such as Mayfield Fund (Marketo, Outreach) and OMERS Capital (Shopify, Crunchbase).

Industry:
Software & Data
Subindustry:
Software

City Rank (San Luis Obispo)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:283

Off Day Trainer is a text messaging program designed with coaches in mind. It scales businesses and clients outside of sessions, personalizes, and automates client communication. To assist people to build and manage the 30-day challenge, people may receive a resource library and training sessions.

Industry:
Healthtech
Subindustry:
Fitness

City Rank (San Luis Obispo)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

WhiteFox Defense Technologies develops and provides drone threat mitigation device the DroneFox. It offers two systems DroneFox Tactical, a portal mobile device which responds to drone threats based on operator feedback or automatically based on preset conditions; DroneFox Fortify, a fixed device which integrates and provides continues automatic protection of vulnerable facilities and critical infrastructure. WhiteFox Defense's device detects small and modified drones in airspace, analyses target drones based on variables including its model, location, and flight pattern, and reroutes. Additionally, its clientele include critical infrastructure protection, homeland security, public safety, and defense. Luke Fox founded WhiteFox Defense in 2016. It has its headquarters in San Luis Obispo in California.

Industry:
Hardware & IoT
Subindustry:
Robotics

City Rank (San Luis Obispo)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:51

Explore the Startup Ecosystem of San Luis Obispo

National Rank

(United States)

118th

new

Regional Rank

(North America)

142nd

7

Global Rank

(WorldWide)

437th

44

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Top Cities for Startups in United States - Ranked by StartupBlink

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2026 National Rank CityGlobal RankTotal ScoreAnnual Growth

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Quantity Score
Quality ScoreBusiness Score
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352.159
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152.371
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127.119
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