92 Top startups in San Carlos for April 2025

We rank Farmer's Business Network, WHILL and Vaxcyte in San Carlos along with 89 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Carlos is part of San Francisco Bay startup ecosystem which ranks #1 globally and #1 in North America.

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Top Unicorn Startups in San Carlos for 2025

Farmers Business Network is the only unicorn in San Carlos raising more than USD 4B. It is the undefined ranked unicorn in North America.

Total amount:1

Best Startups in San Carlos for 2025

SB Score:512

WHILL designs and creates personal mobility products for indoor and outdoor applications. WHILL is making transportation enjoyable and smart for everybody. It aims to change the perception of mobility devices such as wheelchairs and scooters through advanced technology and smart design. It was founded in 2013 and is headquartered in San Carlos, California.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:472

Vaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:447

CelLink is an early-stage hardware startup that is developing a flexible conductive backplane for power electronics, including batteries, light-emitting diodes, wire harnessing, solar cells, and other devices requiring power transmission.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:429

Allakos develops antibody-based therapeutics to treat diseases in which dysregulation of the T-helper type 2 immune response plays a key role in pathology, including allergic disease, inflammation, and diseases characterized by excess production of inflammatory cells. Its antibodies target cell types implicated in allergic and inflammatory responses. Allakos was founded in 2012 and is headquartered in San Carlos, California.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:416

XP Health is a pioneering health tech startup that transforms vision benefits for employees by harnessing the power of machine learning. By providing personalized insights and tailored solutions, XP Health enhances eye care accessibility and supports overall employee well-being, making vision health smarter and more efficient.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:415

Noah Medical is a pioneering manufacturer of advanced medical robotic devices designed for diagnosing and treating patients across diverse healthcare settings. Their innovative solutions enhance precision, improve patient outcomes, and streamline procedures, making healthcare more effective and accessible for everyone.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:405

Clear Labs harnesses the power of next-generation sequencing to simplify complex diagnostics for clinical and applied markets by creating a fully automated platform that brings together dna sequencing, robotics, and cloud-based analytics clear labs democratize genomics applications to deliver increased clarity.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:403

NatureBox is a rapidly growing healthy food brand focusing on snacks, with a large and expanding customer base across all 50 states. With over 400,000 fans on Facebook and 500,000 monthly site visits, NatureBox has donated 50,000 meals to feed the hungry in America in its first year of operation.

Industry:
Foodtech
Subindustry:
Food Manufacturing

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SB Score:401

BigHat Biosciences simplifies the process of designing antibodies and therapeutic proteins, making it easier and more efficient.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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Total amount:92

Top 23 Software & Data Startups in San Carlos for 2025

The top three Software & Data startups in San Carlos have raised more than USD 553M. San Carlos is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Software & Data industry.
SB Score:416

XP Health is a pioneering health tech startup that transforms vision benefits for employees by harnessing the power of machine learning. By providing personalized insights and tailored solutions, XP Health enhances eye care accessibility and supports overall employee well-being, making vision health smarter and more efficient.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:405

Clear Labs harnesses the power of next-generation sequencing to simplify complex diagnostics for clinical and applied markets by creating a fully automated platform that brings together dna sequencing, robotics, and cloud-based analytics clear labs democratize genomics applications to deliver increased clarity.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:401

BigHat Biosciences simplifies the process of designing antibodies and therapeutic proteins, making it easier and more efficient.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Total amount:23

Top 4 Fintech Startups in San Carlos for 2025

The top three Fintech startups in San Carlos have raised more than USD 16.4M. San Carlos is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Fintech industry.
SB Score:283

CapConnectPlus revolutionizes capital markets with their FinTech platform, making investing accessible to all. Their innovative approach modernizes the industry, creating opportunities for individuals to participate in the financial market.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:146

Hustle Fund invests in early-stage startups in software, B2B, fintech, and digital health. Their focus is on supporting innovative entrepreneurs in these industries to help them grow and succeed.

Industry:
Fintech
Subindustry:
Investment

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SB Score:74

Flow is a cutting-edge platform that enhances the consumer payment experience by eliminating paper and facilitating seamless digital purchase journeys. It empowers users to complete transactions effortlessly, transforming the way they shop and pay in a fully digital environment.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (United States)

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Total amount:4

Top 35 Healthtech Startups in San Carlos for 2025

The top three Healthtech startups in San Carlos have raised more than USD 623M. San Carlos is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Healthtech industry.
SB Score:472

Vaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:429

Allakos develops antibody-based therapeutics to treat diseases in which dysregulation of the T-helper type 2 immune response plays a key role in pathology, including allergic disease, inflammation, and diseases characterized by excess production of inflammatory cells. Its antibodies target cell types implicated in allergic and inflammatory responses. Allakos was founded in 2012 and is headquartered in San Carlos, California.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:35

Most Funded Startups in San Carlos for 2025

The top three most funded startups in San Carlos have raised total funding of more than USD 2.18B. Farmer's Business Network has 4.37% more funding than Cellink.
SB Score:447

CelLink is an early-stage hardware startup that is developing a flexible conductive backplane for power electronics, including batteries, light-emitting diodes, wire harnessing, solar cells, and other devices requiring power transmission.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:472

Vaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:92

Top Hiring Startups in San Carlos by Employee Number

The top three hiring startups in San Carlos have an median employee size that is between [501-1000]
SB Score:350

Teradata is a leading multi-cloud data platform company, offering enterprise analytics solutions for businesses of all sizes. Their connected platform helps solve business challenges and drive growth, from initial stages to full scalability.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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Regional Rank (North America)

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SB Score:512

WHILL designs and creates personal mobility products for indoor and outdoor applications. WHILL is making transportation enjoyable and smart for everybody. It aims to change the perception of mobility devices such as wheelchairs and scooters through advanced technology and smart design. It was founded in 2013 and is headquartered in San Carlos, California.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:472

Vaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:92

Explore the Startup Ecosystem of San Carlos

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
-
1
37.971
00.00
00.00
00.00
9th
0
24th
-
2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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