Farmers Business Network maximizes family farmers' profits globally by leveraging Agtech solutions.
We rank Farmer's Business Network, WHILL and Vaxcyte in San Carlos along with 105 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Carlos is part of San Francisco Bay startup ecosystem which ranks #1 globally and #1 in North America.
Farmers Business Network maximizes family farmers' profits globally by leveraging Agtech solutions.
Total amount:1
FBN is an innovative AgTech platform empowering farmers to make informed decisions for sustainable farm profitability.
2nd
WHILLWHILL designs and creates personal mobility products for indoor and outdoor applications. WHILL is making transportation enjoyable and smart for everybody. It aims to change the perception of mobility devices such as wheelchairs and scooters through advanced technology and smart design. It was founded in 2013 and is headquartered in San Carlos, California.
3rd
VaxcyteVaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).
4th
Noah MedicalNoah Medical is a manufacturer of medical robotic devices used to diagnose and treat patients in a variety of settings. The company's devices perform early diagnoses and treatments in advanced clinical settings, allowing hospitals to treat patients earlier and save lives while leaving only minor scars.
5th
XP HealthXP Health is a health tech startup introducing a new kind of vision benefit for employees leveraging machine learning. Founded in 2019 by Antonio Moraes and James Wong, XP Health is an AI-powered vision benefits platform for employees and their families to get frames from the world’s leading designers like Tom Ford, Ray-Ban, Armani, Gucci, Coach. Its proprietary deep learning model uses facial recognition technology that recommends the best frames based on facial dimensions with 98% accuracy. The company is working with companies like Chegg, Zenefits, and Sequoia Consulting Group.
Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, the company set about solving a vexing problem: how to bring true proteomics to the world in a way that accelerates therapeutic development, dramatically improves medical diagnostics, and makes personalized and predictive medicine a reality. The extraordinary team at Nautilus represents a wide spectrum of disciplines and expertise, including protein chemists, chip designers, molecular biologists, data scientists, material scientists, biophysicists, optical engineers, microfluidics engineers, bioinformaticists, software engineers, and more. Nautilus is positioned to revolutionize proteomics, transform the way drugs are developed, and significantly improve the way human health is managed.
Integrated Biosciences develops next-generation therapeutics for age-related diseases. Originating from labs at Harvard, MIT, and UCSB and with breakthrough publications in Nature and Science, Integrated Biosciences has demonstrated the first AI-driven discovery of anti-aging drug candidates, as well as the first novel structural class of antibiotics in 60 years.
8th
CellinkCelLink’s high-conductance circuits integrate busing, fusing, voltage monitoring, and temperature monitoring wiring systems into a single circuit. Our circuits provide much greater control over power and data transmission than traditional round wire – at 1/4th the weight and 1/10th the volume.
9th
Telo TrucksTelo Trucks manufactures cleverly designed, compact electric vehicle trucks for city dwellers and weekend adventurers.
Galvanize Therapeutics is an energy-based medical device technology that provides therapeutic products and services to deliver healthcare solutions. The company aims to become the global leader in delivering medical technology innovations that drive biological processes to treat a range of diseases, starting with treating chronic bronchitis symptoms, cardiac arrhythmias, and solid tumors. It was formed by Apple Tree Partners in 2022.
Ziplines Education, an industry-leading education company, partners with universities to deliver industry-focused certificate courses that prepare professionals for today’s digital-first workforce so individuals can confidently pursue the career they’ve always wanted. The award-winning industry innovator launched in 2017 as GreenFig and relaunched as Ziplines Education in early 2024. Today, dozens of leading U.S. colleges and universities trust Ziplines Education as their continuing education partner, including the University of Virginia School of Continuing and Professional Studies, Texas Tech University, and the University of North Carolina at Charlotte. To learn more about the company, visit ziplines.com and follow them on @ZiplinesEducation on Linkedin, Facebook, Instagram, and YouTube, and on @ZiplinesEdu on Twitter.
Total amount:108
1st
XP HealthXP Health is a health tech startup introducing a new kind of vision benefit for employees leveraging machine learning. Founded in 2019 by Antonio Moraes and James Wong, XP Health is an AI-powered vision benefits platform for employees and their families to get frames from the world’s leading designers like Tom Ford, Ray-Ban, Armani, Gucci, Coach. Its proprietary deep learning model uses facial recognition technology that recommends the best frames based on facial dimensions with 98% accuracy. The company is working with companies like Chegg, Zenefits, and Sequoia Consulting Group.
2nd
SimularSimular develops software that uses AI agents to operate digital interfaces through natural language instructions. The platform interprets user commands to handle actions across desktop and browser environments, allowing repetitive tasks such as information gathering, form interaction, and navigation to run through automated sequences. Simular offers on-device agents along with cloud-based execution options that support remote operation and integration with existing workflows. Its open-source foundation provides transparency into how automations run, giving organizations a way to monitor, adjust, and embed autonomous computer agents into daily processes. This approach helps teams streamline digital work while maintaining clear insight into each automated step.

3rd
Clear LabsClear Labs offers next-generation sequencing and data analytics for infectious disease surveillance and food safety testing. The company's platforms, Clear Dx™ and Clear Safety™, enable rapid identification of pathogens and support public health initiatives. The company focuses on delivering actionable insights to enhance safety and operational efficiency in various sectors.
Total amount:30
1st
VaxcyteVaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).
2nd
Noah MedicalNoah Medical is a manufacturer of medical robotic devices used to diagnose and treat patients in a variety of settings. The company's devices perform early diagnoses and treatments in advanced clinical settings, allowing hospitals to treat patients earlier and save lives while leaving only minor scars.
Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, the company set about solving a vexing problem: how to bring true proteomics to the world in a way that accelerates therapeutic development, dramatically improves medical diagnostics, and makes personalized and predictive medicine a reality. The extraordinary team at Nautilus represents a wide spectrum of disciplines and expertise, including protein chemists, chip designers, molecular biologists, data scientists, material scientists, biophysicists, optical engineers, microfluidics engineers, bioinformaticists, software engineers, and more. Nautilus is positioned to revolutionize proteomics, transform the way drugs are developed, and significantly improve the way human health is managed.
Total amount:42
CapConnect+ is a fintech company that designs and develops cloud-based digital platforms for communication and transactions among corporate issuers, investors, and their banking partners. The company's platform facilitates corporate bond issuance for issuers and assists dealers and investors, promoting simplicity and transparency in the fixed-income markets while digitizing the investment process.
2nd
Hustle FundHustle Fund is a seed fund that invests in early-stage startups operating in software, business-to-business, fintech, and digital health sectors.
Fintech. Flow is a platform upgrading the consumer payment experience and eliminating paper to enable fully-digital purchase journeys
Total amount:5
FBN is an innovative AgTech platform empowering farmers to make informed decisions for sustainable farm profitability.
2nd
CellinkCelLink’s high-conductance circuits integrate busing, fusing, voltage monitoring, and temperature monitoring wiring systems into a single circuit. Our circuits provide much greater control over power and data transmission than traditional round wire – at 1/4th the weight and 1/10th the volume.
3rd
VaxcyteVaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).
Total amount:108
1st
TeradataTeradata is the connected multi-cloud data platform for enterprise analytics company. Our enterprise analytics solve business challenges from start to scale. Only Teradata gives you the flexibility to handle the massive and mixed data workloads of the future, today. Teradata offers analytic data platforms, applications, and services for data warehousing and analytic technologies. The company was founded in January 1979 and is globally headquartered in San Diego, California.
FBN is an innovative AgTech platform empowering farmers to make informed decisions for sustainable farm profitability.
3rd
WHILLWHILL designs and creates personal mobility products for indoor and outdoor applications. WHILL is making transportation enjoyable and smart for everybody. It aims to change the perception of mobility devices such as wheelchairs and scooters through advanced technology and smart design. It was founded in 2013 and is headquartered in San Carlos, California.
4th
VaxcyteVaxcyte is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. The Company’s cell-free protein synthesis platform, comprising the XpressCFTM platform, exclusively licensed from Sutro Biopharma, Inc., together with Vaxcyte’s proprietary know-how, enables the design and production of protein carriers and antigens, the critical building blocks of vaccines, in ways that the Company believes conventional vaccine technologies currently cannot. In addition to its pneumococcal conjugate vaccines in development, VAX-24 and VAX-XP, Vaxcyte is leveraging its proprietary platform to advance other novel vaccines, including a prophylactic vaccine to prevent Group A Strep infections (VAX-A1) and a therapeutic vaccine to treat periodontal disease (VAX-PG).
Total amount:108
FBN is an innovative AgTech platform empowering farmers to make informed decisions for sustainable farm profitability.
2nd
TeradataTeradata is the connected multi-cloud data platform for enterprise analytics company. Our enterprise analytics solve business challenges from start to scale. Only Teradata gives you the flexibility to handle the massive and mixed data workloads of the future, today. Teradata offers analytic data platforms, applications, and services for data warehousing and analytic technologies. The company was founded in January 1979 and is globally headquartered in San Diego, California.
Old Bones Therapy offers a range of products including gift cards, accessories, compression sleeves, and pain creams. With free shipping on orders over $99 and a one-year warranty on all items, customers can easily find relief and comfort for their aches and pains.
Total amount:108
National Rank
(United States)
Regional Rank
(North America)
1st
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Global Rank
(WorldWide)
1st
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