StartupBlink

148 Top startups in Rochester for November 2026

We rank CEIPAL TalentHire, CEIPAL and Vuzix in Rochester along with 145 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Rochester startup ecosystem ranks #222 globally and #65 in United States.

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Best Startups in Rochester for 2026

1st
CEIPAL TalentHire logo
CEIPAL TalentHireSB Score: 561

CEIPAL Cloud Portal is an integrated HCM (human capital management) solution delivers in a single platform from hiring, on-boarding, self-service portal, workforce collaboration, time management, expense management, leaves management and administration, and Payroll data management. Since 2015, CEIPAL has been raising the bar in the HR software industry, with many of our innovations becoming industry-standard. CEIPAL is the first company to put powerful, easy-to-use recruiting &and

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Website
talenthire.ceipal.com
Employee range
251 – 500
Web Traffic (Monthly)
—
Funding amount
$25.3M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
2nd
CEIPAL logo
CEIPALSB Score: 561

CEIPAL offers a comprehensive Cloud HCM solution for seamless hiring and workforce collaboration on a single platform accessible anytime, anywhere.

View Full Page
Website
www.ceipal.com
Employee range
251 – 500
Web Traffic (Monthly)
—
Funding amount
$25.3M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
3rd
Vuzix logo
VuzixSB Score: 445

Vuzix is a supplier of video eyewear products in the consumer, commercial and entertainment markets. The company’s products- personal display devices that offer users a portable high quality viewing experience- provide solutions for mobility, wearable displays and virtual and augmented reality. Vuzix holds over 48 patents and patents pending, as well as numerous IP licenses in the video eyewear field. The company has won 13 Consumer Electronics Show Innovations Awards and several wireless technology innovation awards, among others. Founded in 1997, Vuzix is a public company (OTCBB:VUZI.QB), with offices in Rochester, NY, Oxford, UK and Tokyo, Japan. Vuzix’s high-resolution Video Eyewear Family of consumer products solves the main challenge in viewing video and digital information via portable and mobile devices – the small screen. Vuzix iWear® and Wrap® Video Eyewear are worn like regular glasses and provide the effect of a big screen experience, ranging from 44” to 75”, as seen from 10 feet (~ 3m). They are ideal for use with media players, portable DVD players, gaming consoles, and mobile phones. The company is focused on making its video eyewear the standard mobile equipment for watching news, sports, music videos and movies, and for playing video games on the go. Vuzix is a leading name in Virtual Reality (VR), immersing users in computer-generated worlds. Vuzix VR eyewear enables users to view the world outside their flight simulation cockpit and look around like sitting in the real plane. Look down and to the left to see your landing approach and your view changes automatically. VR software and Vuzix VR eyewear are used in a variety of applications ranging from game and flight simulations to medical applications such as pain and phobia management. Vuzix Augmented Reality (AR) eyewear provides a first-person view of the real world, overlaid with computer-generated data and content. Both digital and optical see-through models provide 2D and 3D support of real world and computer content. Integrated camera systems capture AR markers and targets, enabling a host computer or mobile device to merge the real and virtual worlds. AR technology is catching on quickly in a vast array of applications from hands-free maintenance assistance, virtual engineering/product demonstrations, gaming, simulation, and more.

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Website
www.vuzix.com
Employee range
51 – 100
Web Traffic (Monthly)
—
Funding amount
$48.1M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
4th
AeroSafe Global logo
AeroSafe GlobalSB Score: 432

AeroSafe Global develops and produces aerogels and related materials for temperature-sensitive shipping needs in the United States. Its products are used in various thermal insulation applications to transport biomedical, pharmaceutical, and other temperature-sensitive products. The company provides a reliable, simple, and sustainable temperature sensitive supply chain solutions to the world’s leading biopharma companies. AeroSafe Global delivers cold-chain services for the biopharma industry that results in zero temperature excursions for every client, every product, every time. With proprietary packaging, logistics, and operational services, the company builds customized solutions that ensure the safe delivery of temperature-sensitive biopharmaceuticals.

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Website
www.aerosafeglobal.com
Employee range
101 – 250
Web Traffic (Monthly)
—
Funding amount
$119.7M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
5th
Home Leasing logo
Home LeasingSB Score: 419

Home Leasing is a real estate company that develops, contructs, owns and manages affordable family and senior living communities. Home Leasing currently owns and manages 9 communities through New York, Pennsylvania and Maryland. Our experienced and diverse team strives to improve the lives of our customers and residents, and will aggressively continue to meet and exceed our residents’ needs while providing a fair return to our partners and investors

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Website
www.homeleasing.net
Employee range
101 – 250
Web Traffic (Monthly)
—
Funding amount
$3.6M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
6th
GoNetspeed logo
GoNetspeedSB Score: 416

GoNetspeed offers fast, fiber optic Internet service prioritizing customer satisfaction. Founded by Frank Chiaino, the creator of Fibertech Networks, GoNetspeed delivers high-speed connectivity with a strong emphasis on customer care.

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Website
www.gonetspeed.com
Employee range
11 – 50
Web Traffic (Monthly)
—
Funding amount
$7.5M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
7th
eHealth Technologies™ logo

eHealth Technologies™ (formerly eHealth Global) is a leading health care technology company that advances the delivery of life-altering care. We help to provide fast and seamless access to health care for patients by collecting medical records, test results, and images and organizing them so that physicians have the information they need to provide superior care in a timely manner – in a fast, easy-to-use, digital format. Our team members take great pride in working behind the scenes to help millions of patients benefit from faster access to lifesaving medical services ranging from cancer care to organ transplants to emergency care.

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Website
www.ehealthtechnologies.com
Employee range
501 – 1,000
Web Traffic (Monthly)
—
Funding amount
$44.8M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
8th
Auto Hauler Exchange logo

Arabiers Tours Majestic City offers convenient and reliable Dubai Visa Near Me services right in your vicinity. With a prime location in Colombo Majestic City, Arabiers Tours provides a seamless visa application process for your Dubai travel needs. Their expert team ensures a hassle-free experience, guiding you through the necessary documentation and procedures—they benefit from their exceptional service quality, which is reflected in their high customer ratings and reviews. Whether you are planning a leisure trip or a business visit to Dubai, Arabiers Tours Majestic City is your go-to destination for obtaining your Dubai visa. Trust in their expertise and proximity to cater to all your visa requirements efficiently and effectively.

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Website
www.autohaulerexchange.com
Employee range
11 – 50
Web Traffic (Monthly)
—
Funding amount
$300K
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
9th
OLEDWorks logo
OLEDWorksSB Score: 384

OLEDWorks is a manufacturer of OLED light technology for automotive, general lighting, and specialty applications. Its products offer and active-matrix OLED display, a brightness light panel, and create reliable, cost-effective OLED light engines that enable customers to get organic lights and enrich illuminated spaces. It creates reliable, beautiful, and cost-effective OLED light engines that inspire architects, designers, and manufacturers around the world. OLEDWorks was founded in 2010 and is headquartered in Rochester, New York.

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Website
www.oledworks.com
Employee range
101 – 250
Web Traffic (Monthly)
—
Funding amount
$32.9M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
10th
BioSked logo
BioSkedSB Score: 378

BioSked is an information technology company that develops software for process optimization in healthcare.

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Website
www.biosked.com
Employee range
11 – 50
Web Traffic (Monthly)
—
Funding amount
$850K
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
11th
Vyriad logo
VyriadSB Score: 377

Vyriad is a clinical-stage company developing proprietary oncolytic virus therapies for the treatment of cancers with significant unmet needs. The potentially life-changing oncolytic viral technologies of Vyriad are the result of decades of research by dedicated researchers and clinicians at Mayo Clinic and the University of Miami.

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Website
www.vyriad.com
Employee range
51 – 100
Web Traffic (Monthly)
—
Funding amount
$88.4M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—

Total amount:89

Most Funded Startups in Rochester for 2026

The top three most funded startups in Rochester have raised total funding of more than USD 270M. AeroSafe Global has 0.35% more funding than Vyriad.
1st
AeroSafe Global logo
AeroSafe GlobalSB Score: 432

AeroSafe Global develops and produces aerogels and related materials for temperature-sensitive shipping needs in the United States. Its products are used in various thermal insulation applications to transport biomedical, pharmaceutical, and other temperature-sensitive products. The company provides a reliable, simple, and sustainable temperature sensitive supply chain solutions to the world’s leading biopharma companies. AeroSafe Global delivers cold-chain services for the biopharma industry that results in zero temperature excursions for every client, every product, every time. With proprietary packaging, logistics, and operational services, the company builds customized solutions that ensure the safe delivery of temperature-sensitive biopharmaceuticals.

View Full Page
Website
www.aerosafeglobal.com
Employee range
101 – 250
Web Traffic (Monthly)
—
Funding amount
$119.7M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
2nd
Vyriad logo
VyriadSB Score: 377

Vyriad is a clinical-stage company developing proprietary oncolytic virus therapies for the treatment of cancers with significant unmet needs. The potentially life-changing oncolytic viral technologies of Vyriad are the result of decades of research by dedicated researchers and clinicians at Mayo Clinic and the University of Miami.

View Full Page
Website
www.vyriad.com
Employee range
51 – 100
Web Traffic (Monthly)
—
Funding amount
$88.4M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
3rd
Nucleus RadioPharma logo
Nucleus RadioPharmaSB Score: 343

Nucleus RadioPharma is a new company that was founded to ensure that cancer patients have access to potentially life-saving radiopharmaceuticals by developing technologies to modernise the clinical development, manufacturing, and supply chain of these promising new therapies.

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Website
www.nucleusrad.com
Employee range
1 – 10
Web Traffic (Monthly)
—
Funding amount
$62M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—

Total amount:89

Top Hiring Startups in Rochester by Employee Number

The top three hiring startups in Rochester have an median employee size that is between [251-500]
1st
eHealth Technologies™ logo

eHealth Technologies™ (formerly eHealth Global) is a leading health care technology company that advances the delivery of life-altering care. We help to provide fast and seamless access to health care for patients by collecting medical records, test results, and images and organizing them so that physicians have the information they need to provide superior care in a timely manner – in a fast, easy-to-use, digital format. Our team members take great pride in working behind the scenes to help millions of patients benefit from faster access to lifesaving medical services ranging from cancer care to organ transplants to emergency care.

View Full Page
Website
www.ehealthtechnologies.com
Employee range
501 – 1,000
Web Traffic (Monthly)
—
Funding amount
$44.8M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
2nd
CEIPAL logo
CEIPALSB Score: 561

CEIPAL offers a comprehensive Cloud HCM solution for seamless hiring and workforce collaboration on a single platform accessible anytime, anywhere.

View Full Page
Website
www.ceipal.com
Employee range
251 – 500
Web Traffic (Monthly)
—
Funding amount
$25.3M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
3rd
CEIPAL TalentHire logo
CEIPAL TalentHireSB Score: 561

CEIPAL Cloud Portal is an integrated HCM (human capital management) solution delivers in a single platform from hiring, on-boarding, self-service portal, workforce collaboration, time management, expense management, leaves management and administration, and Payroll data management. Since 2015, CEIPAL has been raising the bar in the HR software industry, with many of our innovations becoming industry-standard. CEIPAL is the first company to put powerful, easy-to-use recruiting &and

View Full Page
Website
talenthire.ceipal.com
Employee range
251 – 500
Web Traffic (Monthly)
—
Funding amount
$25.3M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—
4th
Sign-Speak logo
Sign-SpeakSB Score: 373

Global Alumni brings first-class continuing education from the best universities to ambitious professionals all around the world. They help universities develop and implement transformational e-learning strategies. They help professors create and refine online and blended courses in Spanish and English. They use state of the art technology to create beautiful, engaging course modules. They recruit and support professionals who learn from them. And they do it all with a positive attitude, a collaborative spirit, and a commitment to excellence.

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Website
www.sign-speak.com
Employee range
251 – 500
Web Traffic (Monthly)
—
Funding amount
$3.6M
National Rank(United States)
—
Regional Rank(North America)
—
Global Rank(Worldwide)
—

Total amount:148

Explore More Top Startups

Explore the Startup Ecosystem of Rochester

National Rank

(United States)

65th

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Regional Rank

(North America)

64th

7

Global Rank

(WorldWide)

222nd

15

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Top Cities for Startups in United States - Ranked by StartupBlink

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2026 National Rank CityGlobal RankTotal Score & National ShareAnnual Growth

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