10 Top startups in Potomac for March 2025

We rank Holistic Industries, Sazmining and Topbox in Potomac along with 7 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Potomac is part of Washington DC Area startup ecosystem which ranks #19 globally and #8 in North America.

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Best Startups in Potomac for 2025

SB Score:453

Holistic Industries is an organic medical cannabis company offering wellness solutions. They provide high-quality products to help improve health and well-being. Their focus is on providing natural alternatives for holistic healing.

Industry:
Healthtech
Subindustry:
Cannabis

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SB Score:289

Sazmining provides cryptocurrency mining and consulting services, helping clients navigate the world of digital currency. Specializing in both mining operations and expert guidance, Sazmining is the go-to resource for individuals looking to enter the exciting world of cryptocurrency.

Industry:
Fintech
Subindustry:
Blockchain

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SB Score:288

The startup analyzes customer interactions and feedback from all contact channels within a business. It helps enterprises understand their customers better by collecting and analyzing data from various sources.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:275

ScaleMatters provides comprehensive RevOps-as-a-Service for early and growth-stage B2B companies. It enables businesses to access valuable data and insights quickly and affordably, allowing them to develop an effective Go-to-Market strategy much earlier in their journey.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:210

The SafeCheck Wellness Wallet provides users with easy access to innovative wellness tools and technologies, enhancing their health and well-being. With a user-friendly interface and transformative features, it empowers individuals to manage their wellness journey effectively and conveniently.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SpringGem Weather Information offers free, real-time weather and energy forecasts as a valuable community service. Founded by Menglin Susan, the company is headquartered in North Potomac, Maryland, providing users with essential weather insights to help them make informed decisions for their daily activities.

Industry:
Marketing & Sales
Subindustry:
Marketing & Sales-Other

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SB Score:102

Skyward IT Solutions provides comprehensive IT services including architecture, custom development, project management, continuous integration, security assessment, and test automation for startups. With expertise in PMO implementation and disaster recovery, they ensure efficient and secure technology solutions for businesses.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:27

ZAC introduces a groundbreaking AI platform using Explainable-AI technology for accurate image and video recognition and search. Users can quickly identify people, objects, patterns, and actions with precision and reliability.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:24

BigSpool creates successful consumer brands by leveraging data, automation, and community marketing to identify and fill niche market gaps. They launch products quickly at scale to meet consumer needs, revolutionizing the e-commerce model.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:24

DNA Safe is a B2B SaaS platform that empowers healthcare organizations to perform analytics on encrypted data securely. By ensuring data privacy while enabling insightful analysis, it helps firms leverage sensitive information without compromising security.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Total amount:10

Top 7 Software & Data Startups in Potomac for 2025

The top three Software & Data startups in Potomac have raised more than USD 10.7M. Potomac is part of Washington DC Area startup ecosystem which ranks #11 globally for the Software & Data industry.
SB Score:288

The startup analyzes customer interactions and feedback from all contact channels within a business. It helps enterprises understand their customers better by collecting and analyzing data from various sources.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:275

ScaleMatters provides comprehensive RevOps-as-a-Service for early and growth-stage B2B companies. It enables businesses to access valuable data and insights quickly and affordably, allowing them to develop an effective Go-to-Market strategy much earlier in their journey.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:210

The SafeCheck Wellness Wallet provides users with easy access to innovative wellness tools and technologies, enhancing their health and well-being. With a user-friendly interface and transformative features, it empowers individuals to manage their wellness journey effectively and conveniently.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:7

Top 1 Healthtech Startups in Potomac for 2025

The top three Healthtech startups in Potomac have raised more than USD 113M. Potomac is part of Washington DC Area startup ecosystem which ranks #10 globally for the Healthtech industry.
SB Score:453

Holistic Industries is an organic medical cannabis company offering wellness solutions. They provide high-quality products to help improve health and well-being. Their focus is on providing natural alternatives for holistic healing.

Industry:
Healthtech
Subindustry:
Cannabis

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:1

Top 1 Fintech Startups in Potomac for 2025

The top three Fintech startups in Potomac have raised more than USD 2.45M. Potomac is part of Washington DC Area startup ecosystem which ranks #31 globally for the Fintech industry.
SB Score:289

Sazmining provides cryptocurrency mining and consulting services, helping clients navigate the world of digital currency. Specializing in both mining operations and expert guidance, Sazmining is the go-to resource for individuals looking to enter the exciting world of cryptocurrency.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:1

Most Funded Startups in Potomac for 2025

The top three most funded startups in Potomac have raised total funding of more than USD 123M. Holistic Industries has 14.27% more funding than Topbox.
SB Score:453

Holistic Industries is an organic medical cannabis company offering wellness solutions. They provide high-quality products to help improve health and well-being. Their focus is on providing natural alternatives for holistic healing.

Industry:
Healthtech
Subindustry:
Cannabis

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:288

The startup analyzes customer interactions and feedback from all contact channels within a business. It helps enterprises understand their customers better by collecting and analyzing data from various sources.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:275

ScaleMatters provides comprehensive RevOps-as-a-Service for early and growth-stage B2B companies. It enables businesses to access valuable data and insights quickly and affordably, allowing them to develop an effective Go-to-Market strategy much earlier in their journey.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:10

Top Hiring Startups in Potomac by Employee Number

The top three hiring startups in Potomac have an median employee size that is between [11-50]
SB Score:453

Holistic Industries is an organic medical cannabis company offering wellness solutions. They provide high-quality products to help improve health and well-being. Their focus is on providing natural alternatives for holistic healing.

Industry:
Healthtech
Subindustry:
Cannabis

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:289

Sazmining provides cryptocurrency mining and consulting services, helping clients navigate the world of digital currency. Specializing in both mining operations and expert guidance, Sazmining is the go-to resource for individuals looking to enter the exciting world of cryptocurrency.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:288

The startup analyzes customer interactions and feedback from all contact channels within a business. It helps enterprises understand their customers better by collecting and analyzing data from various sources.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:275

ScaleMatters provides comprehensive RevOps-as-a-Service for early and growth-stage B2B companies. It enables businesses to access valuable data and insights quickly and affordably, allowing them to develop an effective Go-to-Market strategy much earlier in their journey.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:10

Explore the Startup Ecosystem of Potomac

National Rank

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Regional Rank

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8th

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Global Rank

(WorldWide)

19th

1

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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Quality ScoreBusiness Score
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710.966
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251.377
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121.937
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109.679
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