StartupBlink

15 Top startups in Potomac for June 2026

We rank Holistic Industries, Sazmining and scaleMatters in Potomac along with 12 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Potomac is part of Washington DC Area startup ecosystem which ranks #21 globally and #9 in North America.

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Best Startups in Potomac for 2026

SB Score:428

Holistic Industries, Industry mission is to provide patients with the safest cannabis medicine possible. Its medicine is designed to alleviate the symptoms of numerous medical conditions. The company develops and offers a wide range of proprietary strains that increase desired cannabinoids such as cannabidiol (CBD), with its low psychoactivity and lack of other side effects. These high CBD strains have become its foundation for creating safe medication for patients in need.

Industry:
Healthtech
Subindustry:
Cannabis

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SB Score:336

Sazmining's Bitcoin Mining as a Service provides clients direct access to the Bitcoin network, allowing them to mine "wild sats" without relying on exchanges. Driven by renewable energy and fully aligned with client success, Sazmining is redefining the future of sustainable, purpose-driven Bitcoin mining. Hear about us on our podcast: Everything Bitcoin Mining: The Sazmining Podcast

Industry:
Fintech
Subindustry:
Blockchain

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SB Score:287

scaleMatters is a boutique Go-to-Market analytics partner for PE-backed companies, offering GTM data strategy, reporting, and analytics-as-a-service. PortCos of leading PE firms like Accel-KKR, Baird, Edison Partners, JMI Equity, and Hg rely on us to optimize their GTM performance, achieve predictable outcomes, and streamline board reporting. Learn more at scalematters.com.

Industry:
Software & Data
Subindustry:
Data Analytics

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SpringGem Weather Information provides current and forecasted weather and energy information as a free community service. The company was founded by Menglin Susan and is based in North Potomac, Maryland.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:187

The SafeCheck Wellness Wallet empowers users with access to transformative Wellness tools and technology at your fingertips. Now, more than ever, it is paramount for all people to gather, manage and securely share certain wellness information (Prescriptions, Symptoms Status, Sexually Wellness Status, Allergies, Vaccination Status, etc) to protect their homes, family and others around them.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:139

JK BioPharma Solutions, Inc. operates in the healthcare industry focusing on biotechnology business. The company was incorporated in 2013 and is based in Potomac, Maryland.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:100

Privva is an award-winning, cloud-based vendor risk assessment platform delivering value for a diverse customer base across industries including legal, financial services, technology, healthcare, education, and media. The most flexible platform in the market, Privva’s solution streamlines the assessment process from authoring to automatic recurring delivery. Developed with a philosophy that risk is contextual, Privva’s adaptable features enable a tailored approach to assessing risk with an intuitive user interface that drives a responsive experience throughout the process. Privva’s Vendor Security Assessment offering centralizes security questionnaires, risk ratings and scoring of responses for third-parties that have access to enterprise networks or sensitive data. Through the use of Privva’s workflow and templates, the time it takes to assess a vendor is reduced by 75% and annual recertification can be automated. Looking upstream, Privva’s AutoAssess Solution uses machine learning technology to automate the process of responding to client security assessments. The AutoAssess solution saves law firms more than 90% of their time completing this process ensuring resources can be allocated to other critical functions of cybersecurity.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:92

WonderSouq is an innovative technology company at the forefront of developing and designing immersive virtual 3D spaces and advanced 3D engines. WonderSouq specializes in creating unique, interactive virtual environments for businesses and individuals, enabling them to build engaging experiences and drive higher levels of user engagement. WonderSouq's cutting-edge technology powers the creation of dynamic virtual worlds that integrate real-time communication, spatial audio, VR support, and a host of other features, making WonderSouq a leader in the virtual reality space. Core Values: At WonderSouq, core values are deeply embedded in everything it does. WonderSouq is user-centric, focusing on creating value through its services. WonderSouq embraces innovation and leadership, fosters creativity, and maintains transparency in all aspects of its operations. WonderSouq's mission is to empower businesses and individuals in the online 3D world by providing tools and services that are simple, affordable, and accessible. WonderSouq's vision is to make virtual worlds a mainstream service that everyone can enjoy. Competitive Advantage: WonderSouq's competitive advantage lies in its relentless pursuit of innovation and creativity, and its unwavering commitment to value creation with a truly user-centric approach. WonderSouq believes in simplicity, clarity, and empowerment, consistently delivering on its promises while avoiding over-promising, complexity, industry jargon, bureaucracy, and politics. These qualities set WonderSouq apart as the preferred choice for those seeking cutting-edge solutions in a dynamic and ever-evolving market. Proprietary Technology: WonderSouq's technology stack includes: 3D Web Engine Multiplayer Engine Avatar Builder Engine Services: WonderSouq offers expert development services, delivering custom and immersive virtual spaces. WonderSouq's team of senior developers excels in creating bespoke virtual environments, integrating third-party solutions, and engineering 3D experiences tailored to meet the unique needs of its clients. Industries Served: Venues & Exhibitions E-commerce & Social Media Stores Entertainment and Event Organizers Real Estate Sports NGOs Government Initiatives and Entities E-sports and Gaming Mission: To create tools and services that empower businesses and individuals in the online 3D world, making virtual worlds a mainstream, affordable, and simple service for everyone. Vision: To revolutionize how businesses and users interact online by making immersive virtual experiences accessible to all, fostering creativity, and driving engagement in the digital age.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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​Peregrine Advisors Benefit is a data-driven strategy firm that offers services in data management, analytics, and enterprise architecture. The company specializes in developing customized data resource management solutions, focusing on data governance, security, and compliance. Peregrine Advisors Benefit provides services under the General Services Administration (GSA) Multiple Award Schedule Contract #47QTCA23D0028, specifically under Special Item Number (SIN): 54151S. The firm is certified by the U.S. Small Business Administration (SBA) as an 8(a) Certified Minority-Owned Business and by the State of Maryland as a Minority Business Enterprise (MBE), South Asian Business Enterprise (SABE), and Small Disadvantaged Business (SDB). Peregrine Advisors Benefit Inc. is accessible to government clients through various contract vehicles via strategic partnerships. ​

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:49

TerraPulse is the leading developer of satellite-based datasets providing consistent, high-resolution insights about the planet’s changing surface. Our team produced the first global, high-resolution maps of Earth’s tree-canopy and surface-water cover, as well as the world’s first long-term time series of urban growth based on satellite imagery. We combine cutting-edge data science and computational architecture with sound understanding of ecosystems and solid pedigree in remote sensing and Geographic Information Systems. Our algorithms, expertise, and datasets have helped countries monitor their forests for the emerging carbon economy, US states map the distribution of sensitive wildlife, and international nonprofit organizations plan and evaluate the effectiveness of protected areas.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:26

Worth Social, LTD specializes in providing a comprehensive suite of digital marketing services. Since its inception in 2013, the company has focused on helping businesses strategize and implement their creative visions to enhance online presence and engagement. With a dedicated team passionate about driving results, Worth Social offers solutions that encompass the full spectrum of digital marketing, including but not limited to, social media management, content creation, and digital advertising. Catering to a diverse clientele, Worth Social aims to deliver tailored strategies that align with each company's unique goals, ensuring effective and measurable outcomes in their digital marketing efforts.

Industry:
Marketing & Sales
Subindustry:
Content Marketing

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Total amount:15

SB Score:428

Holistic Industries, Industry mission is to provide patients with the safest cannabis medicine possible. Its medicine is designed to alleviate the symptoms of numerous medical conditions. The company develops and offers a wide range of proprietary strains that increase desired cannabinoids such as cannabidiol (CBD), with its low psychoactivity and lack of other side effects. These high CBD strains have become its foundation for creating safe medication for patients in need.

Industry:
Healthtech
Subindustry:
Cannabis

City Rank (Potomac)

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Regional Rank (North America)

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SB Score:336

Sazmining's Bitcoin Mining as a Service provides clients direct access to the Bitcoin network, allowing them to mine "wild sats" without relying on exchanges. Driven by renewable energy and fully aligned with client success, Sazmining is redefining the future of sustainable, purpose-driven Bitcoin mining. Hear about us on our podcast: Everything Bitcoin Mining: The Sazmining Podcast

Industry:
Fintech
Subindustry:
Blockchain

City Rank (Potomac)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:287

scaleMatters is a boutique Go-to-Market analytics partner for PE-backed companies, offering GTM data strategy, reporting, and analytics-as-a-service. PortCos of leading PE firms like Accel-KKR, Baird, Edison Partners, JMI Equity, and Hg rely on us to optimize their GTM performance, achieve predictable outcomes, and streamline board reporting. Learn more at scalematters.com.

Industry:
Software & Data
Subindustry:
Data Analytics

City Rank (Potomac)

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Regional Rank (North America)

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Total amount:15

SB Score:428

Holistic Industries, Industry mission is to provide patients with the safest cannabis medicine possible. Its medicine is designed to alleviate the symptoms of numerous medical conditions. The company develops and offers a wide range of proprietary strains that increase desired cannabinoids such as cannabidiol (CBD), with its low psychoactivity and lack of other side effects. These high CBD strains have become its foundation for creating safe medication for patients in need.

Industry:
Healthtech
Subindustry:
Cannabis

City Rank (Potomac)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:336

Sazmining's Bitcoin Mining as a Service provides clients direct access to the Bitcoin network, allowing them to mine "wild sats" without relying on exchanges. Driven by renewable energy and fully aligned with client success, Sazmining is redefining the future of sustainable, purpose-driven Bitcoin mining. Hear about us on our podcast: Everything Bitcoin Mining: The Sazmining Podcast

Industry:
Fintech
Subindustry:
Blockchain

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:287

scaleMatters is a boutique Go-to-Market analytics partner for PE-backed companies, offering GTM data strategy, reporting, and analytics-as-a-service. PortCos of leading PE firms like Accel-KKR, Baird, Edison Partners, JMI Equity, and Hg rely on us to optimize their GTM performance, achieve predictable outcomes, and streamline board reporting. Learn more at scalematters.com.

Industry:
Software & Data
Subindustry:
Data Analytics

City Rank (Potomac)

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:15

SB Score:428

Holistic Industries, Industry mission is to provide patients with the safest cannabis medicine possible. Its medicine is designed to alleviate the symptoms of numerous medical conditions. The company develops and offers a wide range of proprietary strains that increase desired cannabinoids such as cannabidiol (CBD), with its low psychoactivity and lack of other side effects. These high CBD strains have become its foundation for creating safe medication for patients in need.

Industry:
Healthtech
Subindustry:
Cannabis

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:336

Sazmining's Bitcoin Mining as a Service provides clients direct access to the Bitcoin network, allowing them to mine "wild sats" without relying on exchanges. Driven by renewable energy and fully aligned with client success, Sazmining is redefining the future of sustainable, purpose-driven Bitcoin mining. Hear about us on our podcast: Everything Bitcoin Mining: The Sazmining Podcast

Industry:
Fintech
Subindustry:
Blockchain

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:287

scaleMatters is a boutique Go-to-Market analytics partner for PE-backed companies, offering GTM data strategy, reporting, and analytics-as-a-service. PortCos of leading PE firms like Accel-KKR, Baird, Edison Partners, JMI Equity, and Hg rely on us to optimize their GTM performance, achieve predictable outcomes, and streamline board reporting. Learn more at scalematters.com.

Industry:
Software & Data
Subindustry:
Data Analytics

City Rank (Potomac)

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:15

Most Funded Startups in Potomac for 2026

The top three most funded startups in Potomac have raised total funding of more than USD 118M. Holistic Industries has 38.65% more funding than scaleMatters.
SB Score:428

Holistic Industries, Industry mission is to provide patients with the safest cannabis medicine possible. Its medicine is designed to alleviate the symptoms of numerous medical conditions. The company develops and offers a wide range of proprietary strains that increase desired cannabinoids such as cannabidiol (CBD), with its low psychoactivity and lack of other side effects. These high CBD strains have become its foundation for creating safe medication for patients in need.

Industry:
Healthtech
Subindustry:
Cannabis

City Rank (Potomac)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:287

scaleMatters is a boutique Go-to-Market analytics partner for PE-backed companies, offering GTM data strategy, reporting, and analytics-as-a-service. PortCos of leading PE firms like Accel-KKR, Baird, Edison Partners, JMI Equity, and Hg rely on us to optimize their GTM performance, achieve predictable outcomes, and streamline board reporting. Learn more at scalematters.com.

Industry:
Software & Data
Subindustry:
Data Analytics

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:336

Sazmining's Bitcoin Mining as a Service provides clients direct access to the Bitcoin network, allowing them to mine "wild sats" without relying on exchanges. Driven by renewable energy and fully aligned with client success, Sazmining is redefining the future of sustainable, purpose-driven Bitcoin mining. Hear about us on our podcast: Everything Bitcoin Mining: The Sazmining Podcast

Industry:
Fintech
Subindustry:
Blockchain

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:15

Top Hiring Startups in Potomac by Employee Number

The top three hiring startups in Potomac have an median employee size that is between [11-50]
SB Score:428

Holistic Industries, Industry mission is to provide patients with the safest cannabis medicine possible. Its medicine is designed to alleviate the symptoms of numerous medical conditions. The company develops and offers a wide range of proprietary strains that increase desired cannabinoids such as cannabidiol (CBD), with its low psychoactivity and lack of other side effects. These high CBD strains have become its foundation for creating safe medication for patients in need.

Industry:
Healthtech
Subindustry:
Cannabis

City Rank (Potomac)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:336

Sazmining's Bitcoin Mining as a Service provides clients direct access to the Bitcoin network, allowing them to mine "wild sats" without relying on exchanges. Driven by renewable energy and fully aligned with client success, Sazmining is redefining the future of sustainable, purpose-driven Bitcoin mining. Hear about us on our podcast: Everything Bitcoin Mining: The Sazmining Podcast

Industry:
Fintech
Subindustry:
Blockchain

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

Browse
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SB Score:287

scaleMatters is a boutique Go-to-Market analytics partner for PE-backed companies, offering GTM data strategy, reporting, and analytics-as-a-service. PortCos of leading PE firms like Accel-KKR, Baird, Edison Partners, JMI Equity, and Hg rely on us to optimize their GTM performance, achieve predictable outcomes, and streamline board reporting. Learn more at scalematters.com.

Industry:
Software & Data
Subindustry:
Data Analytics

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SpringGem Weather Information provides current and forecasted weather and energy information as a free community service. The company was founded by Menglin Susan and is based in North Potomac, Maryland.

Industry:
Energy & Environment
Subindustry:
Energy

City Rank (Potomac)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:15

Explore the Startup Ecosystem of Potomac

National Rank

(United States)

new

Regional Rank

(North America)

9th

2

Global Rank

(WorldWide)

21st

3

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152.371
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127.119
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