40 Top startups in Panama City for April 2025

We rank Hero, Lulubit and Eprezto.com in Panama City along with 37 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Panama City startup ecosystem ranks #405 globally and #1 in Panama.

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Best Startups in Panama City for 2025

1st

Hero
SB Score:348

Hero is a cost organization tool for Latam SMBs, eliminating the need for manual tracking. Launched in 2021 and headquartered in Panama City, Panama, Hero streamlines cost management for businesses in a user-friendly digital format.

Industry:
Edtech
Subindustry:
Education-Other

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SB Score:324

Crypto Ramps enables users in Panama, Guatemala, Honduras, and Costa Rica to easily buy, hold, and sell cryptocurrencies, as well as send and receive remittances with minimal fees. This platform provides seamless access to crypto and DeFi services, making digital finance more accessible for local communities.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

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SB Score:320

Eprezto.com is an online platform that provides comprehensive vehicle damage insurance to third parties, offering reliable protection against property damage, medical expenses, accidents, and more. With a secure interface, it ensures users can confidently safeguard their assets and navigate unforeseen incidents.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

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SB Score:316

PayCaddy enables Latam companies to launch financial products with an API based platform. Rather than building fintech from scratch, or dealing with a legacy bank, companies can use PayCaddy to open digital wallets with KYC checks, process online payments, and issue personalized debit and prepaid cards for customers or employees.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

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SB Score:310

Venmetro is an innovative online lending platform in Panama that simplifies access to personal loans. By connecting borrowers with flexible financing options, it empowers individuals to achieve their financial goals with ease and convenience.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (Panama)

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SB Score:307

The CarTongyun intelligent maintenance platform offers precise insights through its extensive database, covering nearly 2 million vehicles. This innovative system empowers users to optimize vehicle maintenance, ensuring efficiency and reliability for all types of vehicles.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

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SB Score:304

Discover the ultimate real estate portal in Panama with comprehensive information on buildings and apartments. Find the perfect property easily and efficiently.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:271

Blueberry is an innovative interface that empowers users to navigate the DeFi landscape seamlessly. It enables borrowing from an internal lending market, providing opportunities for leveraging investments and hedging risks effectively. With Blueberry, users can optimize their DeFi strategies with ease and confidence.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

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SB Score:255

Pine is a decentralized protocol that enables users to borrow and lend using NFT collateral. By leveraging the value of digital assets, Pine offers a seamless and secure way for users to access liquidity while unlocking the potential of their NFTs.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

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10th

ShoeFy
SB Score:237

ShoeFy is a decentralized platform that seamlessly integrates non-fungible tokens (NFTs) and fungible tokens (FTs), enhancing the utility of NFTs. By combining these two token types, ShoeFy offers innovative features and opportunities for users to engage with digital assets in exciting new ways.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

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SB Score:236

Aurora is a startup founded by a passionate group of cryptocurrency enthusiasts dedicated to promoting the adoption of cryptocurrency as a legitimate currency. Their mission is to create an ecosystem where digital currencies can thrive, empowering users to embrace the future of finance.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

0

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Regional Rank (Central America)

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Total amount:40

Top 18 Fintech Startups in Panama City for 2025

The top three Fintech startups in Panama City have raised more than USD 29.5M. Panama City startup ecosystem ranks #163 globally for the Fintech industry.
SB Score:324

Crypto Ramps enables users in Panama, Guatemala, Honduras, and Costa Rica to easily buy, hold, and sell cryptocurrencies, as well as send and receive remittances with minimal fees. This platform provides seamless access to crypto and DeFi services, making digital finance more accessible for local communities.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

0

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Regional Rank (Central America)

0

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Global Rank (WorldWide)

0

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SB Score:320

Eprezto.com is an online platform that provides comprehensive vehicle damage insurance to third parties, offering reliable protection against property damage, medical expenses, accidents, and more. With a secure interface, it ensures users can confidently safeguard their assets and navigate unforeseen incidents.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

0

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Regional Rank (Central America)

0

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Global Rank (WorldWide)

0

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SB Score:316

PayCaddy enables Latam companies to launch financial products with an API based platform. Rather than building fintech from scratch, or dealing with a legacy bank, companies can use PayCaddy to open digital wallets with KYC checks, process online payments, and issue personalized debit and prepaid cards for customers or employees.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

0

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Regional Rank (Central America)

0

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0

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Total amount:18

Top 16 Software & Data Startups in Panama City for 2025

The top three Software & Data startups in Panama City have raised more than USD 570K. Panama City startup ecosystem ranks #355 globally for the Software & Data industry.
SB Score:304

Discover the ultimate real estate portal in Panama with comprehensive information on buildings and apartments. Find the perfect property easily and efficiently.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (Panama)

0

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SB Score:210

Prospect1 connects soccer players worldwide with essential resources and opportunities to enhance their recruitment prospects by professional teams. By leveraging a global network, it empowers athletes to showcase their talent and access pathways to achieve their dreams in professional soccer.

Industry:
Software & Data
Subindustry:
Software

National Rank (Panama)

0

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Regional Rank (Central America)

0

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SB Score:189

SnapXam is an innovative EdTech company that leverages artificial intelligence to provide step-by-step solutions to math problems. Users can simply take a picture of any equation or use a specialized math keyboard to receive instant answers, making math easier and more accessible for students worldwide.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (Panama)

0

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Regional Rank (Central America)

0

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Global Rank (WorldWide)

0

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Total amount:16

Top 3 Ecommerce & Retail Startups in Panama City for 2025

The top three Ecommerce & Retail startups in Panama City have raised more than USD 750K. Panama City startup ecosystem ranks among the top 10 locations in the world for startups in Ecommerce & Retail, holding the falseth position.
SB Score:310

Venmetro is an innovative online lending platform in Panama that simplifies access to personal loans. By connecting borrowers with flexible financing options, it empowers individuals to achieve their financial goals with ease and convenience.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (Panama)

0

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Regional Rank (Central America)

0

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0

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SB Score:85

Trusted Node is building a validator network for proof-of-stake and next-generation blockchains, enabling professional oversight of the network. It offers stakeholders the opportunity to earn yields while actively participating in decision-making regarding the network's node infrastructure.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

National Rank (Panama)

0

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Regional Rank (Central America)

0

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Global Rank (WorldWide)

0

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SB Score:53

TG DAO 3.0 serves as the launchpad for the TG Ecosystem, enabling investment in both traditional and crypto startups. Investors are not just contributors; they become co-owners, actively participating in the decision-making processes that shape the launchpad's operations.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

National Rank (Panama)

0

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Regional Rank (Central America)

0

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Global Rank (WorldWide)

0

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Total amount:3

Most Funded Startups in Panama City for 2025

The top three most funded startups in Panama City have raised total funding of more than USD 29.5M. Factor has 1.08% more funding than ShoeFy.
SB Score:307

The CarTongyun intelligent maintenance platform offers precise insights through its extensive database, covering nearly 2 million vehicles. This innovative system empowers users to optimize vehicle maintenance, ensuring efficiency and reliability for all types of vehicles.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

0

View

Regional Rank (Central America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:237

ShoeFy is a decentralized platform that seamlessly integrates non-fungible tokens (NFTs) and fungible tokens (FTs), enhancing the utility of NFTs. By combining these two token types, ShoeFy offers innovative features and opportunities for users to engage with digital assets in exciting new ways.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

0

View

Regional Rank (Central America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:236

Aurora is a startup founded by a passionate group of cryptocurrency enthusiasts dedicated to promoting the adoption of cryptocurrency as a legitimate currency. Their mission is to create an ecosystem where digital currencies can thrive, empowering users to embrace the future of finance.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

0

View

Regional Rank (Central America)

0

View

Global Rank (WorldWide)

0

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Total amount:40

Top Hiring Startups in Panama City by Employee Number

The top three hiring startups in Panama City have an median employee size that is between [51-100]
SB Score:304

Discover the ultimate real estate portal in Panama with comprehensive information on buildings and apartments. Find the perfect property easily and efficiently.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (Panama)

0

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Regional Rank (Central America)

0

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SB Score:105

BITPOINT Latam is a regulated crypto-to-FIAT exchange that leverages advanced Japanese technology. By adhering to the regulatory standards set by the JFSA license held by BITPOINT Japan, it ensures secure and compliant operations throughout Latin America, providing users with a trusted platform for digital asset transactions.

Industry:
Fintech
Subindustry:
Cryptocurrency

National Rank (Panama)

0

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Regional Rank (Central America)

0

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Global Rank (WorldWide)

0

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SB Score:324

Crypto Ramps enables users in Panama, Guatemala, Honduras, and Costa Rica to easily buy, hold, and sell cryptocurrencies, as well as send and receive remittances with minimal fees. This platform provides seamless access to crypto and DeFi services, making digital finance more accessible for local communities.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (Panama)

0

View

Regional Rank (Central America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:316

PayCaddy enables Latam companies to launch financial products with an API based platform. Rather than building fintech from scratch, or dealing with a legacy bank, companies can use PayCaddy to open digital wallets with KYC checks, process online payments, and issue personalized debit and prepaid cards for customers or employees.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (Panama)

0

View

Regional Rank (Central America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:40

Explore the Startup Ecosystem of Panama City

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Regional Rank

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5th

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Global Rank

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405th

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Top Cities for Startups in Panama - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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