StartupBlink

16 Top startups in Northbrook for June 2026

We rank Homethrive, Emalex Biosciences, Inc. and On Target Laboratories in Northbrook along with 13 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Northbrook is part of Chicago startup ecosystem which ranks #17 globally and #7 in North America.

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Best Startups in Northbrook for 2026

SB Score:414

Homethrive provides care management and personal assistance services to help older adults live at home with dignity and purpose while reducing the stress, strain, work, and worry for their family members. Homethrive's family caregiving platform, Dari, uniquely integrates their digital assistant for coaching, navigation, and resources with expert personal interaction and service coordination to help ease the difficult and stressful responsibility of supporting loved ones who are aging or have special needs.

Industry:
Healthtech
Subindustry:
Health Care

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Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. The company's first development candidate Ecopipam, is a novel compound that has been studied as a potential treatment for many central nervous system (CNS) disorders, including pediatric Tourette Syndrome. Emalex Biosciences was founded in 2018 by Jeff Aronin.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:342

On Target Laboratories, LLC engages in discovering, developing, and commercializing small molecules that target specific pathological cells, when conjugated with fluorescent dyes. It offers folate and other targeting agents that target, lung, uterine, kidney, breast, colon, pancreatic, and prostate cancer cells. The company was incorporated in 2010 and is based in Northbrook, Illinois.

Industry:
Healthtech
Subindustry:
Biotechnology

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Smart Scan Medical Imaging provides medical imaging services to properly and accurately diagnose medical conditions. The company's services include magnetic resonance imaging to generate images of the organs in the body without the use of radiation, CT scan, or computed tomography scan to let patients avail imaging tests at fair prices.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:312

Impossible Objects is a developer of a 3D printing technology used to make objects from sheets of kevlar, carbon fiber, and fiberglass. Its composite-based additive manufacturing (CBAM) technology combines high-performance polymers like nylon and PEEK with long-fiber carbon and fiberglass sheets to deliver complex parts at production speeds and volumes that enable clients to churn out parts that are ready to use in cars, planes, computers, and more. It was founded in 2011 and is headquartered in Northbrook, Illinois.

Industry:
Ecommerce & Retail
Subindustry:
Retail

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SB Score:289

Varicon was co-developed with the construction industry to overcome the major cost management issues for site and office-based staff.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:251

Spark Hire is an easy to use video interviewing platform with 4,000+ customers conducting video interviews in over 100 countries. Since launching in 2012, Spark Hire has become the fastest growing video interviewing platform. Organizations of all sizes are utilizing Spark Hire to make better hires faster than ever before.

Industry:
Social & Leisure
Subindustry:
Digital Media

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SB Score:222

DwellSocial empowers neighborhoods by aggregating demand for meals from the restaurants people love and then leverages the power of each area to bring restaurant pop-ups to suburban areas. DwellSocial also empowers restaurants to expand their service area and reach new customers with orders that are all close to one another. These efficiencies allow restaurants to redefine their customer base and service area.

Industry:
Social & Leisure
Subindustry:
Social & Leisure-Other

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SB Score:143

Speroteck offers comprehensive eCommerce solutions, including extensions, customizations, and integrations to enhance functionality. They also provide SEO and Paid-Search services to boost your site's visibility. Let Speroteck take care of all your eCommerce needs and help your business thrive online.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Consider IT Done Technologies specializes in blockchain and Web3 technologies, offering a range of services aimed at enhancing business operations through innovative digital solutions. The company boasts a team of international developers and technology professionals dedicated to leveraging the potential of blockchain to address complex business challenges. With a focus on creating value for businesses in the internet industry, Consider IT Done Technologies develops custom solutions that harness the power of blockchain technology to improve efficiency, security, and transparency in various business processes.

Industry:
Fintech
Subindustry:
Blockchain

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SB Score:84

Shred Spot can bring your papers to us or we can pick them up from your office, home or storage location. Please give us a call and let us help you prevent identity theft and theft of your important company information while helping the environment by recycling. Timing : Mon to Fri 8:00am to 5:00pm, Sat - Sun Closed Address : 3141 MacArthur Blvd, Northbrook, IL 60062

Industry:
Energy & Environment
Subindustry:
Cleantech

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Total amount:16

SB Score:414

Homethrive provides care management and personal assistance services to help older adults live at home with dignity and purpose while reducing the stress, strain, work, and worry for their family members. Homethrive's family caregiving platform, Dari, uniquely integrates their digital assistant for coaching, navigation, and resources with expert personal interaction and service coordination to help ease the difficult and stressful responsibility of supporting loved ones who are aging or have special needs.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Northbrook)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. The company's first development candidate Ecopipam, is a novel compound that has been studied as a potential treatment for many central nervous system (CNS) disorders, including pediatric Tourette Syndrome. Emalex Biosciences was founded in 2018 by Jeff Aronin.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:342

On Target Laboratories, LLC engages in discovering, developing, and commercializing small molecules that target specific pathological cells, when conjugated with fluorescent dyes. It offers folate and other targeting agents that target, lung, uterine, kidney, breast, colon, pancreatic, and prostate cancer cells. The company was incorporated in 2010 and is based in Northbrook, Illinois.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:16

SB Score:414

Homethrive provides care management and personal assistance services to help older adults live at home with dignity and purpose while reducing the stress, strain, work, and worry for their family members. Homethrive's family caregiving platform, Dari, uniquely integrates their digital assistant for coaching, navigation, and resources with expert personal interaction and service coordination to help ease the difficult and stressful responsibility of supporting loved ones who are aging or have special needs.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. The company's first development candidate Ecopipam, is a novel compound that has been studied as a potential treatment for many central nervous system (CNS) disorders, including pediatric Tourette Syndrome. Emalex Biosciences was founded in 2018 by Jeff Aronin.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:342

On Target Laboratories, LLC engages in discovering, developing, and commercializing small molecules that target specific pathological cells, when conjugated with fluorescent dyes. It offers folate and other targeting agents that target, lung, uterine, kidney, breast, colon, pancreatic, and prostate cancer cells. The company was incorporated in 2010 and is based in Northbrook, Illinois.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:16

SB Score:414

Homethrive provides care management and personal assistance services to help older adults live at home with dignity and purpose while reducing the stress, strain, work, and worry for their family members. Homethrive's family caregiving platform, Dari, uniquely integrates their digital assistant for coaching, navigation, and resources with expert personal interaction and service coordination to help ease the difficult and stressful responsibility of supporting loved ones who are aging or have special needs.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. The company's first development candidate Ecopipam, is a novel compound that has been studied as a potential treatment for many central nervous system (CNS) disorders, including pediatric Tourette Syndrome. Emalex Biosciences was founded in 2018 by Jeff Aronin.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:342

On Target Laboratories, LLC engages in discovering, developing, and commercializing small molecules that target specific pathological cells, when conjugated with fluorescent dyes. It offers folate and other targeting agents that target, lung, uterine, kidney, breast, colon, pancreatic, and prostate cancer cells. The company was incorporated in 2010 and is based in Northbrook, Illinois.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:16

Most Funded Startups in Northbrook for 2026

The top three most funded startups in Northbrook have raised total funding of more than USD 495M. Emalex Biosciences, Inc. has 1.73% more funding than On Target Laboratories.

Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. The company's first development candidate Ecopipam, is a novel compound that has been studied as a potential treatment for many central nervous system (CNS) disorders, including pediatric Tourette Syndrome. Emalex Biosciences was founded in 2018 by Jeff Aronin.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:342

On Target Laboratories, LLC engages in discovering, developing, and commercializing small molecules that target specific pathological cells, when conjugated with fluorescent dyes. It offers folate and other targeting agents that target, lung, uterine, kidney, breast, colon, pancreatic, and prostate cancer cells. The company was incorporated in 2010 and is based in Northbrook, Illinois.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:414

Homethrive provides care management and personal assistance services to help older adults live at home with dignity and purpose while reducing the stress, strain, work, and worry for their family members. Homethrive's family caregiving platform, Dari, uniquely integrates their digital assistant for coaching, navigation, and resources with expert personal interaction and service coordination to help ease the difficult and stressful responsibility of supporting loved ones who are aging or have special needs.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Northbrook)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:16

Top Hiring Startups in Northbrook by Employee Number

The top three hiring startups in Northbrook have an median employee size that is between [51-100]
SB Score:414

Homethrive provides care management and personal assistance services to help older adults live at home with dignity and purpose while reducing the stress, strain, work, and worry for their family members. Homethrive's family caregiving platform, Dari, uniquely integrates their digital assistant for coaching, navigation, and resources with expert personal interaction and service coordination to help ease the difficult and stressful responsibility of supporting loved ones who are aging or have special needs.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:143

Speroteck offers comprehensive eCommerce solutions, including extensions, customizations, and integrations to enhance functionality. They also provide SEO and Paid-Search services to boost your site's visibility. Let Speroteck take care of all your eCommerce needs and help your business thrive online.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. The company's first development candidate Ecopipam, is a novel compound that has been studied as a potential treatment for many central nervous system (CNS) disorders, including pediatric Tourette Syndrome. Emalex Biosciences was founded in 2018 by Jeff Aronin.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:342

On Target Laboratories, LLC engages in discovering, developing, and commercializing small molecules that target specific pathological cells, when conjugated with fluorescent dyes. It offers folate and other targeting agents that target, lung, uterine, kidney, breast, colon, pancreatic, and prostate cancer cells. The company was incorporated in 2010 and is based in Northbrook, Illinois.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Northbrook)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:16

Explore the Startup Ecosystem of Northbrook

National Rank

(United States)

new

Regional Rank

(North America)

7th

1

Global Rank

(WorldWide)

17th

2

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Top Cities for Startups in United States - Ranked by StartupBlink

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2026 National Rank CityGlobal RankTotal ScoreAnnual Growth

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Quantity Score
Quality ScoreBusiness Score
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352.159
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152.371
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1
127.119
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