767 Top startups in Houston for April 2025

We rank Avelo Airlines, Tekmetric and MAJORITY in Houston along with 764 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Houston startup ecosystem ranks #48 globally and #19 in United States.

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Top Unicorn Startups in Houston for 2025

Three startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in Houston have raised more than USD 6.1B.
SB Score:640

HighRadius offers cloud-based Autonomous Software for the Office of the CFO. The company products provide value to a wide range of customers and are especially relevant to industries like consumer products, manufacturing, distribution, energy, and others that sell products or provide a service to other businesses.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:563

Axiom Space offers commercial human spaceflight services, providing access to the ISS now and the upcoming Axiom Station in 2024. Leading the industry, they enable individuals to experience space travel firsthand.

Industry:
Transportation
Subindustry:
Aerospace

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SB Score:446

Solugen is a biotech startup that transforms plant-based materials into high-quality chemicals using its unique hydrogen peroxide technology, developed by a team of MIT experts. This innovative approach distinguishes Solugen in the industry, promoting sustainable practices while delivering exceptional chemical products.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:3

Best Startups in Houston for 2025

SB Score:643

Avelo Airlines offers affordable fares, convenient travel options, and a caring customer experience with its Soul of Service culture. Operating a fleet of Boeing Next-Generation 737 aircraft, Avelo Airlines serves 27 popular destinations across the U.S.

Industry:
Transportation
Subindustry:
Aviation

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SB Score:523

Revolutionize your auto repair shop with a comprehensive digital platform for vehicle inspections, repair orders, inventory management, job tracking, customer updates, and more. Streamline operations and enhance customer communication with ease.

Industry:
Software & Data
Subindustry:
SaaS

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SB Score:520

Introducing the pioneering digital financial platform designed specifically for migrants. Experience seamless money transfers, secure storage, and convenient banking services all in one place. Join us on our mission to revolutionize how migrants manage their finances globally.

Industry:
Fintech
Subindustry:
Online Banking

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SB Score:512

WizeHire: The go-to hiring solution for small businesses, offering user-friendly and effective tools. Hire with ease and confidence, streamlining your recruitment process.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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ChartSpan revolutionizes healthcare data management by creating a secure platform for patients to aggregate electronic records, wearable device data, and genetic information. Their innovative technology converts paper records to digital, improving patient outcomes and drug efficacy through partnerships with healthcare stakeholders.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:500

MacroFab builds millions of custom-manufactured PCBA products every year through its North American factory lines. The company's easy-to-use platform reduces upfront costs and complexity while making it easier for companies of any size and at any stage of product development to bring products to market quickly and efficiently. By enhancing transparency and traceability, our technology platform helps teams maintain resiliency in the face of rapidly changing conditions by integrating design data, getting early risk feedback, and managing production around fast-changing conditions.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:497

Intuitive Machines provides innovative engineering solutions where energy, medicine, and aerospace meet. We offer cutting-edge services at the unique convergence of these industries, pushing boundaries and driving progress forward.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:491

Ontop streamlines global team operations by handling international hiring, payments, taxes, onboarding, and payroll. Simplify your processes and focus on growing your business with ease.

Industry:
Fintech
Subindustry:
Fintech-Other

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SB Score:487

Charming Charlie operates a chain of stores offering stylish jewelry and accessories. Their stores provide customers with a wide selection of fashionable items to enhance their outfits and express their personal style.

Industry:
Ecommerce & Retail
Subindustry:
Retail

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SB Score:486

Preventice Solutions is a privately-held company that offers a portfolio of mobile cardiac health solutions and services. It is a developer of mobile health solutions and remote monitoring services, connecting patients, clinicians, and hospitals.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:484

The Virtuix Omni™ is a groundbreaking virtual reality platform that allows users to move freely and naturally in virtual worlds. With over 3,000 units sold and featured in major media outlets, the Omni is an affordable and compact omni-directional treadmill that enables users to walk, run, and jump in 360 degrees. This innovative technology provides an immersive experience with applications in gaming, training, fitness, healthcare, architecture, virtual workplaces, events, tourism, and multi-person adventures.

Industry:
Social & Leisure
Subindustry:
Digital Media

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Total amount:767

Top 122 Healthtech Startups in Houston for 2025

The top three Healthtech startups in Houston have raised more than USD 662M. Houston startup ecosystem ranks #19 globally for the Healthtech industry.

ChartSpan revolutionizes healthcare data management by creating a secure platform for patients to aggregate electronic records, wearable device data, and genetic information. Their innovative technology converts paper records to digital, improving patient outcomes and drug efficacy through partnerships with healthcare stakeholders.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:486

Preventice Solutions is a privately-held company that offers a portfolio of mobile cardiac health solutions and services. It is a developer of mobile health solutions and remote monitoring services, connecting patients, clinicians, and hospitals.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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SB Score:454

Next Level Urgent Care offers specialized healthcare services with a focus on urgent care and medicine. Their team provides efficient and accessible medical care, ensuring patients receive the attention they need in a timely manner.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Total amount:122

Top 243 Software & Data Startups in Houston for 2025

The top three Software & Data startups in Houston have raised more than USD 214M. Houston startup ecosystem ranks #51 globally for the Software & Data industry.
SB Score:523

Revolutionize your auto repair shop with a comprehensive digital platform for vehicle inspections, repair orders, inventory management, job tracking, customer updates, and more. Streamline operations and enhance customer communication with ease.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United States)

0

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SB Score:512

WizeHire: The go-to hiring solution for small businesses, offering user-friendly and effective tools. Hire with ease and confidence, streamlining your recruitment process.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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SB Score:463

GoCo.io offers software that helps businesses simplify their human resources systems. The software solution includes hiring and onboarding procedures, a centralized system to record and organize all employees’ documents and data, payroll integration, benefits selection processes, personal records database, and more. GoCo.io Inc was launched by Nir Leibovich, Jason J. Wang, and Michael Gugel in 2015 and is based in Houston, Texas.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Total amount:243

Top 51 Fintech Startups in Houston for 2025

The top three Fintech startups in Houston have raised more than USD 256M. Houston startup ecosystem ranks #48 globally for the Fintech industry.
SB Score:520

Introducing the pioneering digital financial platform designed specifically for migrants. Experience seamless money transfers, secure storage, and convenient banking services all in one place. Join us on our mission to revolutionize how migrants manage their finances globally.

Industry:
Fintech
Subindustry:
Online Banking

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:491

Ontop streamlines global team operations by handling international hiring, payments, taxes, onboarding, and payroll. Simplify your processes and focus on growing your business with ease.

Industry:
Fintech
Subindustry:
Fintech-Other

National Rank (United States)

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SB Score:467

Sentai Holdings, a Houston-based anime company, offers a wide range of engaging content for fans of Japanese animation. With a focus on clarity and quality, Sentai Holdings strives to provide the best viewing experience for anime enthusiasts.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (United States)

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Total amount:51

Most Funded Startups in Houston for 2025

The top three most funded startups in Houston have raised total funding of more than USD 905M. Alleviant Medical has 0.53% more funding than MacroFab.
SB Score:500

MacroFab builds millions of custom-manufactured PCBA products every year through its North American factory lines. The company's easy-to-use platform reduces upfront costs and complexity while making it easier for companies of any size and at any stage of product development to bring products to market quickly and efficiently. By enhancing transparency and traceability, our technology platform helps teams maintain resiliency in the face of rapidly changing conditions by integrating design data, getting early risk feedback, and managing production around fast-changing conditions.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (United States)

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MetOx creates advanced high temperature superconductors using YBCO for improved performance. Discover the future of superconducting technology with our second generation products.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

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Total amount:767

Top Hiring Startups in Houston by Employee Number

The top three hiring startups in Houston have an median employee size that is between [5001-10000]
SB Score:487

Charming Charlie operates a chain of stores offering stylish jewelry and accessories. Their stores provide customers with a wide selection of fashionable items to enhance their outfits and express their personal style.

Industry:
Ecommerce & Retail
Subindustry:
Retail

National Rank (United States)

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Regional Rank (North America)

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SB Score:392

TripleTPlus provides roadside assistance services for transportation, freight shipping, and travel industries. Offering support for logistics and transportation needs, TripleTPlus ensures smooth operations and peace of mind for businesses on the move.

Industry:
Transportation
Subindustry:
Automotive

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SB Score:643

Avelo Airlines offers affordable fares, convenient travel options, and a caring customer experience with its Soul of Service culture. Operating a fleet of Boeing Next-Generation 737 aircraft, Avelo Airlines serves 27 popular destinations across the U.S.

Industry:
Transportation
Subindustry:
Aviation

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SB Score:460

Celebal Technologies US excels in Data Science, Big Data, and Enterprise Cloud solutions, delivering top-tier software services that empower businesses to leverage data effectively. Their innovative approach enhances performance and efficiency, enabling organizations to unlock the full potential of their data assets.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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Total amount:767

Explore the Startup Ecosystem of Houston

National Rank

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19th

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Regional Rank

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22nd

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Global Rank

(WorldWide)

48th

4

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
-
1
37.971
00.00
00.00
00.00
9th
0
24th
-
2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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