110 Top startups in Carlsbad for June 2025

We rank Ezoic, GLO Pharma and Airspace in Carlsbad along with 107 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Carlsbad is part of San Diego startup ecosystem which ranks #25 globally and #10 in North America.

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Best Startups in Carlsbad for 2025

SB Score:518

Ezoic is a platform that uses machine learning to optimize websites for digital publishers and owners. It helps improve user experience and increase website revenue.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:463

Glo Pharma develops cutting-edge aesthetic skincare products. Currently operating in stealth mode, the company is revolutionizing the healthcare industry with innovative solutions for skincare.

Industry:
Healthtech
Subindustry:
Life Sciences

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SB Score:461

Airspace was created in 2016 to solve the problems that plagued time-critical deliveries. After more than a decade in logistics, Nick Bulcao teamed up with Ryan Rusnak to build the industry’s most technologically advanced platform in order to expedite deliveries, improve accuracy, and provide full transparency for critical shipments. Headquartered in Carlsbad, California, Airspace has grown to over 200 members and counting. Their reach now extends overseas, where the Airspace B.V. office in Amsterdam supports their rapid international expansion. They serve a growing list of industries that rely on time-critical shipping, including healthcare, aerospace, and manufacturing. Airspace’s technology is revolutionizing the industry by automating a wildly outdated manual process. Proprietary algorithms and machine learning techniques provide instant quotes, optimized routing, and rapid driver dispatch. They are the only logistics company that pairs the most advanced technology with real-time communication on every shipment.

Industry:
Software & Data
Subindustry:
Software

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SB Score:422

SynergEyes creates innovative hybrid contact lenses using cutting-edge technology. Enhancing vision with a unique design, these lenses provide a comfortable and clear experience.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:418

Nalu Medical creates innovative medical devices for various applications. Their cutting-edge products are designed to revolutionize the healthcare industry, providing advanced solutions for improved patient care and treatment outcomes.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:402

Acutus Medical develops medical technologies to treat complex cardiac arrhythmia. The company's platform displays the heart’s true activation pattern, turning the chaos of a complex arrhythmia into a clear vision for electrophysiologists. Acutus Medical is a privately funded company founded in 2011 and based in Carlsbad, California. Its products are co-developed in the U.S. and Europe with an exceptional team of medical scientists, biomedical engineers, and other professionals. It was founded in 2011 and headquartered in Carlsbad, California.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:398

Medsphere Systems offers open-source healthcare software solutions, empowering providers with innovative technology. Their user-friendly platform enhances efficiency and patient care, revolutionizing the industry.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:396

Discover and book venues and group accommodations for travel and events with ease. Simplify the planning process and find inspiration in one convenient marketplace for consumers and commerce.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Argonaut specializes in contract manufacturing for biopharmaceutical, diagnostics, and life science companies. They offer efficient and reliable services to help organizations bring their products to market.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:110

Top 28 Healthtech Startups in Carlsbad for 2025

The top three Healthtech startups in Carlsbad have raised more than USD 678M. Carlsbad is part of San Diego startup ecosystem which ranks #4 globally for the Healthtech industry.
SB Score:463

Glo Pharma develops cutting-edge aesthetic skincare products. Currently operating in stealth mode, the company is revolutionizing the healthcare industry with innovative solutions for skincare.

Industry:
Healthtech
Subindustry:
Life Sciences

City Rank (Carlsbad)

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Regional Rank (North America)

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SB Score:422

SynergEyes creates innovative hybrid contact lenses using cutting-edge technology. Enhancing vision with a unique design, these lenses provide a comfortable and clear experience.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Carlsbad)

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Regional Rank (North America)

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SB Score:418

Nalu Medical creates innovative medical devices for various applications. Their cutting-edge products are designed to revolutionize the healthcare industry, providing advanced solutions for improved patient care and treatment outcomes.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Carlsbad)

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Regional Rank (North America)

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Total amount:28

Top 27 Software & Data Startups in Carlsbad for 2025

The top three Software & Data startups in Carlsbad have raised more than USD 215M. Carlsbad is part of San Diego startup ecosystem which ranks #26 globally for the Software & Data industry.
SB Score:518

Ezoic is a platform that uses machine learning to optimize websites for digital publishers and owners. It helps improve user experience and increase website revenue.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

City Rank (Carlsbad)

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Regional Rank (North America)

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SB Score:461

Airspace was created in 2016 to solve the problems that plagued time-critical deliveries. After more than a decade in logistics, Nick Bulcao teamed up with Ryan Rusnak to build the industry’s most technologically advanced platform in order to expedite deliveries, improve accuracy, and provide full transparency for critical shipments. Headquartered in Carlsbad, California, Airspace has grown to over 200 members and counting. Their reach now extends overseas, where the Airspace B.V. office in Amsterdam supports their rapid international expansion. They serve a growing list of industries that rely on time-critical shipping, including healthcare, aerospace, and manufacturing. Airspace’s technology is revolutionizing the industry by automating a wildly outdated manual process. Proprietary algorithms and machine learning techniques provide instant quotes, optimized routing, and rapid driver dispatch. They are the only logistics company that pairs the most advanced technology with real-time communication on every shipment.

Industry:
Software & Data
Subindustry:
Software

City Rank (Carlsbad)

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Regional Rank (North America)

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SB Score:350

Proficio, an award-winning cyber security service provider, helps customers to detect and prevent security breaches effectively.

Industry:
Software & Data
Subindustry:
Cloud

City Rank (Carlsbad)

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Regional Rank (North America)

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Total amount:27

Top 7 Ecommerce & Retail Startups in Carlsbad for 2025

The top three Ecommerce & Retail startups in Carlsbad have raised more than USD 144M. Carlsbad is part of San Diego startup ecosystem which ranks #39 globally for the Ecommerce & Retail industry.
SB Score:396

Discover and book venues and group accommodations for travel and events with ease. Simplify the planning process and find inspiration in one convenient marketplace for consumers and commerce.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

City Rank (Carlsbad)

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Regional Rank (North America)

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CommonGrounds Workspace offers an innovative Workplace-as-a-Service solution that prioritizes human needs. This enterprise-grade platform provides a dynamic and collaborative work environment for businesses.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

City Rank (Carlsbad)

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Regional Rank (North America)

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SB Score:285

Phoenix Footwear Group offers stylish women's footwear for every occasion. Elevate your look with our diverse collection of shoes designed to make you feel confident and comfortable. Choose Phoenix Footwear Group for fashion-forward footwear that complements your unique style.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

City Rank (Carlsbad)

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Regional Rank (North America)

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Total amount:7

Most Funded Startups in Carlsbad for 2025

The top three most funded startups in Carlsbad have raised total funding of more than USD 824M. Ostendo Technologies has 0.43% more funding than ChromaCode.
SB Score:371

Ostendo Technologies creates innovative solid-state lighting displays for a wide range of markets. Their products cater to commercial, consumer, and government needs, offering cutting-edge technology that enhances visual experiences.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

City Rank (Carlsbad)

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SB Score:387

ChromaCode specializes in molecular diagnostics with a focus on bioinformatics, offering cutting-edge solutions for genetic analysis. Their innovative technology provides accurate and efficient results, revolutionizing the field of molecular diagnostics.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Carlsbad)

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Regional Rank (North America)

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SB Score:402

Acutus Medical develops medical technologies to treat complex cardiac arrhythmia. The company's platform displays the heart’s true activation pattern, turning the chaos of a complex arrhythmia into a clear vision for electrophysiologists. Acutus Medical is a privately funded company founded in 2011 and based in Carlsbad, California. Its products are co-developed in the U.S. and Europe with an exceptional team of medical scientists, biomedical engineers, and other professionals. It was founded in 2011 and headquartered in Carlsbad, California.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Carlsbad)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:110

Top Hiring Startups in Carlsbad by Employee Number

The top three hiring startups in Carlsbad have an median employee size that is between [1001-5000]
SB Score:363

Arlo offers high-definition security cameras, smart doorbells, and lighting that can be easily connected to the internet. With options for HD and 4K resolution, Arlo's products provide top-notch surveillance for peace of mind.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

City Rank (Carlsbad)

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SB Score:461

Airspace was created in 2016 to solve the problems that plagued time-critical deliveries. After more than a decade in logistics, Nick Bulcao teamed up with Ryan Rusnak to build the industry’s most technologically advanced platform in order to expedite deliveries, improve accuracy, and provide full transparency for critical shipments. Headquartered in Carlsbad, California, Airspace has grown to over 200 members and counting. Their reach now extends overseas, where the Airspace B.V. office in Amsterdam supports their rapid international expansion. They serve a growing list of industries that rely on time-critical shipping, including healthcare, aerospace, and manufacturing. Airspace’s technology is revolutionizing the industry by automating a wildly outdated manual process. Proprietary algorithms and machine learning techniques provide instant quotes, optimized routing, and rapid driver dispatch. They are the only logistics company that pairs the most advanced technology with real-time communication on every shipment.

Industry:
Software & Data
Subindustry:
Software

City Rank (Carlsbad)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:110

Explore the Startup Ecosystem of Carlsbad

National Rank

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Regional Rank

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10th

1

Global Rank

(WorldWide)

24th

2

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2025 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
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852.643
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315.515
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4th
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139.115
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0
6th
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1
128.476
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