StartupBlink

131 Top startups in Buffalo for July 2026

We rank Azuna Fresh, Kangarootime and Anysphere in Buffalo along with 128 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Buffalo startup ecosystem ranks #142 globally and #45 in United States.

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Best Startups in Buffalo for 2026

1st
Azuna Fresh logo
Azuna FreshSB Score: 430

Azuna Fresh offers an all-natural hand-crafted gel made from Australian tea trees that safely deliver anti-microbial tree oil into the air using the natural airflow in a room.

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Website
azunafresh.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$3M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Kangarootime logo
KangarootimeSB Score: 428

Kangarootime helps childcare professionals with a cloud-based mobile application that collects payments, automates 'check-in' and 'check-out,' and streamlines communication and compliance. Every care center can create a better connection with the families that they serve. Kangarootime.com automates check-in and child-specific instructions for daily care.

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Website
www.kangarootime.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$40.2M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Anysphere logo
AnysphereSB Score: 419

Anysphere is an applied research lab focused on automating coding processes. The company develops software and models to create a human-AI programmer, aiming for a significant increase in programming effectiveness. This hybrid approach allows for faster iteration and control over complex codebases.

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Website
anysphere.co
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$3.4B
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Realbricks logo
RealbricksSB Score: 418

Realbricks is a proptech company that democratizes real estate investing. They offer primary and secondary offerings that are compliant with SEC guidelines. Build your real estate portfolio brick by brick.

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Website
www.realbricks.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$7.7M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
5th
Viridi Parente logo
Viridi ParenteSB Score: 411

Viridi Parente is a disruptive energy company that builds power systems which employ their proprietary architecture. The company's products are clean, sustainable power sources that replace century old distributed energy platforms, such as fossil fuel, lead-acid batteries and other outdated technologies.

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Website
viridiparente.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$133M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
6th
Synacor logo
SynacorSB Score: 401

Synacor's online content, portal and comprehensive front-end technology solutions enable MSOs, ISPs and telecommunications companies to bundle, promote and deliver narrowband and broadband premium content and services as part of existing Internet access products. Its solutions offer the combined strength of a flexible portal framework, a robust provisioning platform, a unified back-end and a network of in-demand standard and premium content enabling service providers to maintain critical contact with consumers as they shift from screen-to-screen while seeking increasingly personalized entertainment experiences.

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Website
www.synacor.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$29M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
7th
Circuit Clinical logo
Circuit ClinicalSB Score: 401

Circuit Clinical was born from the experiences of a physician conducting clinical research in his busy private practice. From the core belief that patients prefer to learn about clinical research from healthcare providers they trust, came the vision for Circuit Clinical. Since 2015 we've built one of the largest Integrated Research Organizations [IRO] in the US. Our focus on physician and participant engagement gives us a distinct advantage with the identification of motivated participants through direct HIPAA compliant Electronic Health Record (EHR) review. Coupled with our technology products that enhance the participant and physician experience, Circuit Clinical provides our network of more than 6 million patients, our physicians, and our sponsor partners with a new path forward in clinical research.

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Website
www.circuitclinical.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$56.9M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
8th
Targetprocess logo
TargetprocessSB Score: 365

TargetProcess provides agile project management software and helps software development companies reduce the complexity of software project management. It supports Scrum, Extreme Programming and other agile processes and won two Jolt Productivity Awards in 2006 and 2008.

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Website
www.targetprocess.com/3
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$5M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
9th
Ognomy logo
OgnomySB Score: 361

End to end virtual sleep apnea care

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Website
ognomy.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$2.8M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
10th
BetterMynd logo
BetterMyndSB Score: 360

BetterMynd is an online therapy platform for college students that aims to improve access to mental health services and reduce the stigma associated with mental illness in young adults. It is enabling college students to get the mental health care they require by leveraging its provider network and the power of teletherapy.

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Website
www.bettermynd.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$975K
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
11th
CleanFiber logo
CleanFiberSB Score: 354

CleanFiber makes high-performance, carbon-negative building insulation from recycled corrugated cardboard. The company is fully commercial and rapidly scaling up production from its first facility in Buffalo, NY.

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Website
www.cleanfiber.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$105.9M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:79

Most Funded Startups in Buffalo for 2026

The top three most funded startups in Buffalo have raised total funding of more than USD 3.61B. Anysphere has 24.37% more funding than Viridi Parente.
1st
Anysphere logo
AnysphereSB Score: 419

Anysphere is an applied research lab focused on automating coding processes. The company develops software and models to create a human-AI programmer, aiming for a significant increase in programming effectiveness. This hybrid approach allows for faster iteration and control over complex codebases.

View Full Page
Website
anysphere.co
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$3.4B
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Viridi Parente logo
Viridi ParenteSB Score: 411

Viridi Parente is a disruptive energy company that builds power systems which employ their proprietary architecture. The company's products are clean, sustainable power sources that replace century old distributed energy platforms, such as fossil fuel, lead-acid batteries and other outdated technologies.

View Full Page
Website
viridiparente.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$133M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
CleanFiber logo
CleanFiberSB Score: 354

CleanFiber makes high-performance, carbon-negative building insulation from recycled corrugated cardboard. The company is fully commercial and rapidly scaling up production from its first facility in Buffalo, NY.

View Full Page
Website
www.cleanfiber.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$105.9M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:79

Top Hiring Startups in Buffalo by Employee Number

The top three hiring startups in Buffalo have an median employee size that is between [1001-5000]
1st
Computer Task Group logo
Computer Task GroupSB Score: 271

Computer Task Group, Incorporated (CTG) provides information technology (IT) staffing and solutions primarily in North America and Europe. Its services encompass the IT business solution life cycle, including phases for planning, developing, implementing, managing, and maintaining the IT solution. The company's IT staffing services comprise recruiting, retaining, and managing IT talent for its clients, including both large organizations with multiple locations and high-volume IT requirements, and companies that need to augment their own staff on a flexible basis. The company's IT solutions range from helping clients assess their business needs and identifying the IT solutions to meet these needs, to the delivery of services that comprise the selection and implementation of packaged software, as well as the design, construction, testing, and integration of new systems. CTG focuses on vertical markets including technology service providers, healthcare, and financial services. The company was founded in 1966 and is headquartered in Buffalo, New York

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Website
www.ctg.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
2nd
Allient logo
AllientSB Score: 232

Allient designs motion control and power technology solutions for industrial applications.

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Website
www.allient.com
Employee range
1,001 – 5,000
Web Traffic (Monthly)
Funding amount
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
3rd
Anysphere logo
AnysphereSB Score: 419

Anysphere is an applied research lab focused on automating coding processes. The company develops software and models to create a human-AI programmer, aiming for a significant increase in programming effectiveness. This hybrid approach allows for faster iteration and control over complex codebases.

View Full Page
Website
anysphere.co
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$3.4B
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)
4th
Viridi Parente logo
Viridi ParenteSB Score: 411

Viridi Parente is a disruptive energy company that builds power systems which employ their proprietary architecture. The company's products are clean, sustainable power sources that replace century old distributed energy platforms, such as fossil fuel, lead-acid batteries and other outdated technologies.

View Full Page
Website
viridiparente.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$133M
National Rank(United States)
Regional Rank(North America)
Global Rank(Worldwide)

Total amount:131

Explore More Top Startups

Explore the Startup Ecosystem of Buffalo

National Rank

(United States)

45th

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Regional Rank

(North America)

66th

6

Global Rank

(WorldWide)

142nd

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