StartupBlink

145 Top startups in Uruguay for July 2026

We rank Directa24, Data4Sales and nocnoc in Uruguay along with 142 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Uruguay startup ecosystem ranks #60 globally and #5 in South America.

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Best Startups in Uruguay for 2026

1st
Directa24 logo
Directa24SB Score: 499

Directa24 is the leading payment solution in emerging markets, offering various online payment options in local currency. From Cash Payments to Credit Cards and Online Banking, Directa24 provides a seamless and convenient way for users to make transactions worldwide.

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Website
directa24.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$253M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
2nd
Data4Sales logo
Data4SalesSB Score: 437

Hellocare provides an integrated telehealth and virtual care platform featuring software, hardware, and AI-assisted services tailored for hospitals, home care, and primary care providers. The platform supports capabilities such as virtual nursing, virtual patient observation (“eSitter”), telehealth consultations, remote patient monitoring, and remote examination kits. It also includes telemedicine carts and secure communication features like audio/video calling, messaging, and workflow management. AI-powered functions cover patient privacy protection, fall prevention, activity monitoring, and ambient documentation. The solution integrates with major EHR systems and complies with healthcare regulations such as HIPAA, HITRUST, ISO 27001, and SOC.

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Website
www.data4sales.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$58.4M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
3rd
nocnoc logo
nocnocSB Score: 433

Our cross-border eCommerce platform enables Latin American marketplaces to enter the cross-border world, and empowers international sellers to increase their selling volumes in Latin America. Forget long and frustrating international adventures. Reward your customers with a comfortable domestic-feeling shopping experience no matter where the products are coming from.

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Website
www.nocnocstore.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$23M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
4th
zSpace logo
zSpaceSB Score: 423

ZSpace is a system that integrates into users’ normal lives with desktop virtual reality and allows them to move in and out of zSpace back to the real world. This experience is enabled by a combination of polarized eyewear with high definition stereopsis, integrated head tracking with full-motion parallax, and a precision interactive stylus. The system is focused on the learning market, specifically STEM education, medical instruction, corporate training, research, and design. zSpace was launched in 2007 and headquartered in Sunnyvale, California.

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Website
zspace.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$66.6M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
5th
POK - Proof of Knowledge logo

POK - Proof of Knowledge is a blockchain-based credentialing platform that enables institutions and companies to issue tamper-proof digital credentials, diplomas, and microcredentials as NFTs. Built for education, professional certification, and workforce development, POK supports real-time verification, global traceability, and lifelong recognition. All credentials are compliant with Open Badge 3.0 and ELM Europass standards, and interoperable with digital wallets, identity frameworks, and verification ecosystems. POK is trusted by institutions across Latin America, the U.S., Europe, and Asia to issue secure, transparent credentials that certify real-world skills and learning achievements.

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Website
www.pok.tech
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$12M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
6th
Meitre logo
MeitreSB Score: 394

Meitre is a guest manager for restaurants to book tables based on demand trends, rotate tables efficiently, introduce dynamic pricing techinques, host events, and book tables with credit cards Half of the Latin America Top 50 list–including 2 of the top 10 restaurants in the World–use Meitre to increase profit as much as 30% by optimizing table allocation, limiting low margin bookings at peak hours, and eliminating no-shows using tickets, deposits and credit card guarantees.

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Website
meitre.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$1.7M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
7th
Bunker DB logo
Bunker DBSB Score: 389

We are a martech company specialized in helping marketing teams to be more efficient in their decision-making process by using data, science and AI. Our technology centralizes an unlimited number of information, from multiple platforms and devices, and displays it in a friendly interface for further analysis. With 9+ years of experience and 10 offices, we are one of the leading marketing analysis platforms in Latam. Our proprietary technology is currently used in 20+ countries by 1.2k brands, including Walmart, Nestlé, L'Oréal, Scotiabank, KFC, Glaxo, Samsung, Pepsico, Tigo, Telefónica, Liberty and Itaú

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Website
bunkerdb.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$7.4M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
8th
Vopero logo
VoperoSB Score: 389

Second-hand fashion marketplace promoting circular economy in Latin America.

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Website
www.vopero.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$11.5M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
9th
Infinia logo
InfiniaSB Score: 388

Infinia Corporation is a solar energy technology company and the developer of the PowerDish, a proprietary solar power generation product that converts solar energy into electricity. The PowerDish is expected to be sold globally beginning in late 2010 and will be initially sold to energy asset developers, utilities, commercial companies and others engaged in deploying large scale solar asset projects.

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Website
www.infiniaweb.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$90.1M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
10th
Bankingly logo
BankinglySB Score: 352

Founded in 2015, Bankingly is a fintech company with the vision of transforming the way in which financial institutions in emerging markets promote their digital channel and, therefore, facilitate the financial inclusion of millions of people around the world. The provision of technologies hosted in the cloud, with a SaaS business model, based on the number of active users that each institution achieves, allows Bankingly clients to adjust their costs to the benefits achieved. Through a brief, optimized implementation process with high functionality and cybersecurity standards, the Bankingly platform offers a mobile application, a transactional website, a chatbot and multiple other products. Today, more than 1,500,000 people from more than 100 entities trust Bankingly's technology.

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Website
bankingly.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$18.8M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
11th
Axenya logo
AxenyaSB Score: 336

Axenya leverages the power of data to deliver personalized health, greater control, and cost savings. They design solutions for managing a company's corporate health.

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Website
www.axenya.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$16M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)

Total amount:84

Most Funded Startups in Uruguay for 2026

The top three most funded startups in Uruguay have raised total funding of more than USD 410M. Directa24 has 1.81% more funding than Infinia.
1st
Directa24 logo
Directa24SB Score: 499

Directa24 is the leading payment solution in emerging markets, offering various online payment options in local currency. From Cash Payments to Credit Cards and Online Banking, Directa24 provides a seamless and convenient way for users to make transactions worldwide.

View Full Page
Website
directa24.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$253M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
2nd
Infinia logo
InfiniaSB Score: 388

Infinia Corporation is a solar energy technology company and the developer of the PowerDish, a proprietary solar power generation product that converts solar energy into electricity. The PowerDish is expected to be sold globally beginning in late 2010 and will be initially sold to energy asset developers, utilities, commercial companies and others engaged in deploying large scale solar asset projects.

View Full Page
Website
www.infiniaweb.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$90.1M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
3rd
zSpace logo
zSpaceSB Score: 423

ZSpace is a system that integrates into users’ normal lives with desktop virtual reality and allows them to move in and out of zSpace back to the real world. This experience is enabled by a combination of polarized eyewear with high definition stereopsis, integrated head tracking with full-motion parallax, and a precision interactive stylus. The system is focused on the learning market, specifically STEM education, medical instruction, corporate training, research, and design. zSpace was launched in 2007 and headquartered in Sunnyvale, California.

View Full Page
Website
zspace.com
Employee range
101 – 250
Web Traffic (Monthly)
Funding amount
$66.6M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)

Total amount:84

Top Hiring Startups in Uruguay by Employee Number

The top three hiring startups in Uruguay have an median employee size that is between [251-500]
1st
GeneXus logo
GeneXusSB Score: 266

GeneXus is a web and mobile application development powerhouse, building enterprise software and applications that harness big data and power business intelligence from any device. It applies smart technology to business challenges, crafting custom software solutions for Fortune 500 corporations, and governments and nonprofit organizations, around the world. In addition to a portfolio of cutting-edge tools for iOS, Android, Windows 8, and [BlackBerry](http://www.crunchbase.com/organization/blackberry), GeneXus is the sole U.S. distributor of the GeneXus software development suite. Developers and IT consultants of GeneXus are led by owner and CTO, Veronica Buitron, engineer enterprise applications that seamlessly integrate data feeds and streamline informed collaboration, in real-time. Under the leadership of CEO, Dane Drotts, GeneXus supports a multitude of charitable organizations and startup incubators. GeneXus was founded in 1988 and is headquartered in Montevideo. It is a product of ARTech Consultores.

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Website
www.genexus.com/en
Employee range
501 – 1,000
Web Traffic (Monthly)
Funding amount
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
2nd
Data4Sales logo
Data4SalesSB Score: 437

Hellocare provides an integrated telehealth and virtual care platform featuring software, hardware, and AI-assisted services tailored for hospitals, home care, and primary care providers. The platform supports capabilities such as virtual nursing, virtual patient observation (“eSitter”), telehealth consultations, remote patient monitoring, and remote examination kits. It also includes telemedicine carts and secure communication features like audio/video calling, messaging, and workflow management. AI-powered functions cover patient privacy protection, fall prevention, activity monitoring, and ambient documentation. The solution integrates with major EHR systems and complies with healthcare regulations such as HIPAA, HITRUST, ISO 27001, and SOC.

View Full Page
Website
www.data4sales.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
$58.4M
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
3rd
Prex logo
PrexSB Score: 268

Prex is digital financial services platform, with the mission of democratizing access to financial products and services across LATAM through our digital account and mobile APP in a seamless way, promoting financial inclusion and cross border payments. We offer digital banking services giving our customers the power to manage their entire financial life from a single super-app. From everyday spending, domestic and international transfers, bill payments and personal finance management, to personal loans, currency exchange and easy-access to stock trading and investments. Prex digital account and international Mastercard card have no issuance, maintenance or renewal costs. More than 50% of LATAM population is unbanked or underbanked, and with little or no access to financial products or credit. We provide financial solutions and help them build digital credit history, promoting their financial inclusion. Prex was founded in Uruguay in 2015, launched in Argentina in 2019 and Peru in 2021. With more than 1 million customers, 250k loans granted, and presence in three markets, Prex is available in both Android and IOS platforms.

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Website
prexcard.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)
4th
Trafilea logo
TrafileaSB Score: 189

Trafilea is an e-commerce company that creates global direct-to-consumer brands that are driven by meaningful goalsTrafilea .create experiences, spark movements, and illuminate communities of millions in the United States and around the world. Trafilea transforms industries by solving problems and making people happier.

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Website
trafilea.com
Employee range
251 – 500
Web Traffic (Monthly)
Funding amount
National Rank(Uruguay)
Regional Rank(South America)
Global Rank(Worldwide)

Total amount:145

Explore More Top Startups

Explore the Startup Ecosystem of Uruguay

Population

(Uruguay)

3.4 Million

new

Regional Rank

(South America)

5th

0

Global Rank

(WorldWide)

60th

5

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Top Cities for Startups in Uruguay - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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