68 Top startups in Karlsruhe for April 2025

We rank Workwise, INERATEC and Probably Genetic in Karlsruhe along with 65 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Karlsruhe startup ecosystem ranks #269 globally and #12 in Germany.

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Best Startups in Karlsruhe for 2025

SB Score:513

Connecting companies and job seekers effortlessly, our platform equips organizations with essential tools to find the perfect team members. Streamlining the recruitment process, we aim to facilitate meaningful connections at any stage of a company's growth.

Industry:
Marketing & Sales
Subindustry:
Marketing & Sales-Other

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SB Score:414

INERATEC offers a wide range of solutions, from pilot applications to chemical plants. They make sustainable, CO2-neutral, and cost-effective e-fuels and e-products available to all. They provide reactors suitable for fluctuating renewable energy applications.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (Germany)

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SB Score:403

Probably Genetic supports rare genetic disease patients with innovative solutions. Our platform connects patients with resources, research, and personalized support to improve their quality of life. Join us in our mission to make a difference in the lives of those facing genetic challenges.

Industry:
Healthtech
Subindustry:
Life Sciences

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SB Score:401

Flaregames develops and publishes free-to-play mobile games for phones and tablets. Their focus is on creating engaging and immersive experiences for players on the go.

Industry:
Social & Leisure
Subindustry:
Gaming

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SB Score:398

Daedalus creates technology for automated small series production, offering flexible manufacturing solutions.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:371

Restube provides a variety of safety buoys to ensure water enthusiasts can enjoy their activities without worry. Our products offer peace of mind and protection for all water-related adventures.

Industry:
Social & Leisure
Subindustry:
Sports

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SB Score:345

Revolutionize your workflow with our SaaS platform for test automation and RPA. Streamline software processes and increase efficiency easily.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:345

understand.ai leads in AI-driven data annotation for autonomous driving, making AD/ADAS projects of any size feasible with its UAI Automation Engine. Backed by 70+ experts in AI, automotive, and cloud technologies, understand.ai boasts years of global data annotation experience, driving innovation and accuracy in the industry.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:338

An online marketplace connects employers with temporary workers, offering a convenient platform for finding short-term gigs. Users can easily browse and apply for various job opportunities, streamlining the process of securing temporary work.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

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SB Score:331

HQS Quantum Simulations uses quantum algorithms to forecast molecular properties for the specialty chemicals and pharmaceutical industries, providing accurate predictions for companies seeking innovative solutions.

Industry:
Healthtech
Subindustry:
Pharmaceuticals

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11th

Bavest
SB Score:316

Bavest, a German fintech company, empowers retail investors and businesses with advanced tools and in-depth financial data insights. By leveraging Bavest's platform, users can make informed investment decisions and develop smarter financial strategies based on comprehensive data analysis.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (Germany)

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Total amount:68

Top 32 Software & Data Startups in Karlsruhe for 2025

The top three Software & Data startups in Karlsruhe have raised more than USD 48.9M. Karlsruhe startup ecosystem ranks #291 globally for the Software & Data industry.
SB Score:345

Revolutionize your workflow with our SaaS platform for test automation and RPA. Streamline software processes and increase efficiency easily.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:345

understand.ai leads in AI-driven data annotation for autonomous driving, making AD/ADAS projects of any size feasible with its UAI Automation Engine. Backed by 70+ experts in AI, automotive, and cloud technologies, understand.ai boasts years of global data annotation experience, driving innovation and accuracy in the industry.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (Germany)

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Regional Rank (Western Europe)

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SB Score:316

Bavest, a German fintech company, empowers retail investors and businesses with advanced tools and in-depth financial data insights. By leveraging Bavest's platform, users can make informed investment decisions and develop smarter financial strategies based on comprehensive data analysis.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (Germany)

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Regional Rank (Western Europe)

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Total amount:32

Top 5 Ecommerce & Retail Startups in Karlsruhe for 2025

The top three Ecommerce & Retail startups in Karlsruhe have raised more than USD 105K. Karlsruhe startup ecosystem ranks #164 globally for the Ecommerce & Retail industry.
SB Score:338

An online marketplace connects employers with temporary workers, offering a convenient platform for finding short-term gigs. Users can easily browse and apply for various job opportunities, streamlining the process of securing temporary work.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

National Rank (Germany)

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SB Score:104

Vanguard Automation specializes in transforming ideas into reality, offering a full spectrum of services from small-scale prototyping to large-scale industrial automation. Their expertise includes photonic wire bonding, optical packaging, assembly, and communication, delivering cutting-edge solutions tailored to meet unique technological needs.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

National Rank (Germany)

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The company specializes in implementing PIM systems with KennerPIM and developing online stores with Sopware and Oxid eSales. They solve data integration challenges using BigData, Semantic Web, and AI technologies.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (Germany)

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Total amount:5

Top 7 Edtech Startups in Karlsruhe for 2025

The top three Edtech startups in Karlsruhe have raised more than USD 81.9K. Karlsruhe startup ecosystem ranks #144 globally for the Edtech industry.
SB Score:209

DIGITALL, based in Karlsruhe, Germany, offers software and online tools for managing and protecting business services. Founded in 2021, they specialize in digitizing data, enhancing network security, and providing cloud storage solutions.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (Germany)

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SB Score:200

Memetis, a spin-off from Karlsruhe Institute of Technology, offers innovative solutions for various industries. Their cutting-edge technology enhances efficiency and productivity, making them a leader in the market. Join Memetis in revolutionizing the way businesses operate.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (Germany)

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SB Score:99

Infinity Maps is a visual knowledge management tool that helps users organize and share information in a single, interconnected knowledge map. Collect, structure, and connect personal or collaborative knowledge easily with this software.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (Germany)

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Total amount:7

Most Funded Startups in Karlsruhe for 2025

The top three most funded startups in Karlsruhe have raised total funding of more than USD 294M. INERATEC has 3.23% more funding than HQS Quantum Simulations.
SB Score:414

INERATEC offers a wide range of solutions, from pilot applications to chemical plants. They make sustainable, CO2-neutral, and cost-effective e-fuels and e-products available to all. They provide reactors suitable for fluctuating renewable energy applications.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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HQS Quantum Simulations uses quantum algorithms to forecast molecular properties for the specialty chemicals and pharmaceutical industries, providing accurate predictions for companies seeking innovative solutions.

Industry:
Healthtech
Subindustry:
Pharmaceuticals

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:398

Daedalus creates technology for automated small series production, offering flexible manufacturing solutions.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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Total amount:68

Top Hiring Startups in Karlsruhe by Employee Number

The top three hiring startups in Karlsruhe have an median employee size that is between [101-250]
SB Score:209

DIGITALL, based in Karlsruhe, Germany, offers software and online tools for managing and protecting business services. Founded in 2021, they specialize in digitizing data, enhancing network security, and providing cloud storage solutions.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:513

Connecting companies and job seekers effortlessly, our platform equips organizations with essential tools to find the perfect team members. Streamlining the recruitment process, we aim to facilitate meaningful connections at any stage of a company's growth.

Industry:
Marketing & Sales
Subindustry:
Marketing & Sales-Other

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:414

INERATEC offers a wide range of solutions, from pilot applications to chemical plants. They make sustainable, CO2-neutral, and cost-effective e-fuels and e-products available to all. They provide reactors suitable for fluctuating renewable energy applications.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:401

Flaregames develops and publishes free-to-play mobile games for phones and tablets. Their focus is on creating engaging and immersive experiences for players on the go.

Industry:
Social & Leisure
Subindustry:
Gaming

National Rank (Germany)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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Total amount:68

Explore the Startup Ecosystem of Karlsruhe

National Rank

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Regional Rank

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71st

12

Global Rank

(WorldWide)

269th

4

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Top Cities for Startups in Germany - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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