Probably Genetic is on a mission to improve the lives of patients living with rare disease.
We rank Probably Genetic, INERATEC and Faregames in Karlsruhe along with 90 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Karlsruhe startup ecosystem ranks #304 globally and #15 in Germany.
Category:
Probably Genetic is on a mission to improve the lives of patients living with rare disease.
2nd
INERATECINERATEC develops innovative synthetic fuels and power-to-X plants aimed at replacing fossil fuels with carbon-neutral alternatives. The company focuses on creating sustainable energy solutions for transportation and everyday products, contributing to a post-fossil fuel economy.
3rd
FaregamesFlaregames is a fast-growing mobile game publisher and developer that is focused on creating and bringing fun, high-quality, free-to-play games to smartphones and tablets. The company has a pipeline of games in development internally, and is working with some of the most talented mobile game developers from around the world to bring their games to mobile gamer. Flaregames publishes and builds games across a number of top genres including Tower Defense (and Offense), Real-Time Strategy, RPG, and world building games. The company has also recently signed publishing partnerships with Subatomic Studios, Superweapon, and FuzzyCube Software as part of its portfolio publishing initiative to bring AAA titles from world-class studios to market. Based in sunny Karlsruhe, Germany, flaregames is located just an hour from Frankfurt, and two hours from Paris by train. The company was founded in 2011 by a group of industry veterans, including Klaas Kersting, the former CEO and founder of online games leader Gameforge. Flaregames is committed to an environment free of office politics under the belief that in the games industry, it should be fun to come to work and rewarding to be a part of a great team. The company is venture-backed, having raised $23 Million to employ the best people in mobile games and ensure the company fulfills its destiny of becoming a major publisher reaching and entertaining the massive global audience of mobile gamers.
4th
DaedalusDaedalus is building the world’s most advanced factories for precision components. With $40M in funding from Khosla Ventures, Addition, NGP Capital and Y Combinator, and a team from OpenAI, Google, SpaceX and Blue Horizon, we’re building software-defined factories where we’re producing parts for companies in semiconductor, aerospace, medical, energy, defense and more.
5th
LinearityLinearity is a software company whose products are designed to breathe new life into the design process and provide innovative ways of visualizing ideas. Known previously for the vector graphic design software Vectornator, Linearity’s product lineup includes vector and motion design tools like Linearity Curve and Linearity Move, tailored for both marketing professionals and enthusiasts. Linearity’s products are used to create millions of design assets every week.
6th
EnablUsing the enabl Digital Platform, customers can easily link their warehouse systems to our digital interface. Customers can quickly connect their vehicles to our drivers and, with a few clicks, schedule material transportation that meets their needs. Depending on the mission, a driver or an autonomous driving system executes the transport order remotely. Our transport services are available for reservation at any time, with only the hours of service being charged.

7th
RestubeRestube manufactures a range of safety buoys that offers safety for water-related activities. Restube’s range of buoy include basic, classic, swim, sports, and lifeguard. The buoy consists of a trigger that inflates through a CO2 cartridge when pulled. It can be used for surfing, on-board, outdoor, swimming, and professionally. Restube was founded in 2012 by Christopher Fuhrhop, Christian Schwarzkopf, and Marius Kunkis and is based in Germany.
8th
askuiaskui contributes to the vision of a functional digital world through an innovative UI test automation solution. For us here at askui, people are the center of the work that we do. That's why we bring the human touch into theautomation process through askui James. We don't just test UIs according to rigid methods, we understand them like a human.
HQS Quantum Simulations is developing quantum algorithms to predict molecular properties for performance materials, specialty chemicals and pharmaceutical companies. The development of specialty chemicals, performance materials, agrochemicals and pharmaceuticals is an iterative, time-consuming and often very expensive process: Designing products based on functional molecules, formulations or solid-state compounds requires many – often hundreds – subsequent synthesis, formulation and testing steps to yield the desired specifications. Simulations are a powerful tool to decrease the time-to-market and decrease cost for R&D and product development cycles, but can’t be used in an efficient way in many cases or is simply not advanced enough to tackle certain problems. Shifting from conventional to quantum computers promises to overcome these hurdles, but is not yet available for the chemical and pharmaceutical industry.

10th
InStaffThe InStaff & Jobs GmbH is an online marketplace where businesses can browse through a curated list of potential employees and book them directly online. Currently InStaff only offers hostesses & event staff in germany, but in the longterm InStaff will expand to other verticals as well as other countries. Book hostesses & event staff online: https://en.instaff.jobs
11th
FreshtasteFreshtaste is a startup that delivers fresh, nutritious, and delicious food directly from the Smart Fridge to the table.
Total amount:93
Probably Genetic is on a mission to improve the lives of patients living with rare disease.
2nd
INERATECINERATEC develops innovative synthetic fuels and power-to-X plants aimed at replacing fossil fuels with carbon-neutral alternatives. The company focuses on creating sustainable energy solutions for transportation and everyday products, contributing to a post-fossil fuel economy.
3rd
FaregamesFlaregames is a fast-growing mobile game publisher and developer that is focused on creating and bringing fun, high-quality, free-to-play games to smartphones and tablets. The company has a pipeline of games in development internally, and is working with some of the most talented mobile game developers from around the world to bring their games to mobile gamer. Flaregames publishes and builds games across a number of top genres including Tower Defense (and Offense), Real-Time Strategy, RPG, and world building games. The company has also recently signed publishing partnerships with Subatomic Studios, Superweapon, and FuzzyCube Software as part of its portfolio publishing initiative to bring AAA titles from world-class studios to market. Based in sunny Karlsruhe, Germany, flaregames is located just an hour from Frankfurt, and two hours from Paris by train. The company was founded in 2011 by a group of industry veterans, including Klaas Kersting, the former CEO and founder of online games leader Gameforge. Flaregames is committed to an environment free of office politics under the belief that in the games industry, it should be fun to come to work and rewarding to be a part of a great team. The company is venture-backed, having raised $23 Million to employ the best people in mobile games and ensure the company fulfills its destiny of becoming a major publisher reaching and entertaining the massive global audience of mobile gamers.
Total amount:93
Probably Genetic is on a mission to improve the lives of patients living with rare disease.
2nd
INERATECINERATEC develops innovative synthetic fuels and power-to-X plants aimed at replacing fossil fuels with carbon-neutral alternatives. The company focuses on creating sustainable energy solutions for transportation and everyday products, contributing to a post-fossil fuel economy.
3rd
FaregamesFlaregames is a fast-growing mobile game publisher and developer that is focused on creating and bringing fun, high-quality, free-to-play games to smartphones and tablets. The company has a pipeline of games in development internally, and is working with some of the most talented mobile game developers from around the world to bring their games to mobile gamer. Flaregames publishes and builds games across a number of top genres including Tower Defense (and Offense), Real-Time Strategy, RPG, and world building games. The company has also recently signed publishing partnerships with Subatomic Studios, Superweapon, and FuzzyCube Software as part of its portfolio publishing initiative to bring AAA titles from world-class studios to market. Based in sunny Karlsruhe, Germany, flaregames is located just an hour from Frankfurt, and two hours from Paris by train. The company was founded in 2011 by a group of industry veterans, including Klaas Kersting, the former CEO and founder of online games leader Gameforge. Flaregames is committed to an environment free of office politics under the belief that in the games industry, it should be fun to come to work and rewarding to be a part of a great team. The company is venture-backed, having raised $23 Million to employ the best people in mobile games and ensure the company fulfills its destiny of becoming a major publisher reaching and entertaining the massive global audience of mobile gamers.
Total amount:93
Probably Genetic is on a mission to improve the lives of patients living with rare disease.
2nd
INERATECINERATEC develops innovative synthetic fuels and power-to-X plants aimed at replacing fossil fuels with carbon-neutral alternatives. The company focuses on creating sustainable energy solutions for transportation and everyday products, contributing to a post-fossil fuel economy.
3rd
FaregamesFlaregames is a fast-growing mobile game publisher and developer that is focused on creating and bringing fun, high-quality, free-to-play games to smartphones and tablets. The company has a pipeline of games in development internally, and is working with some of the most talented mobile game developers from around the world to bring their games to mobile gamer. Flaregames publishes and builds games across a number of top genres including Tower Defense (and Offense), Real-Time Strategy, RPG, and world building games. The company has also recently signed publishing partnerships with Subatomic Studios, Superweapon, and FuzzyCube Software as part of its portfolio publishing initiative to bring AAA titles from world-class studios to market. Based in sunny Karlsruhe, Germany, flaregames is located just an hour from Frankfurt, and two hours from Paris by train. The company was founded in 2011 by a group of industry veterans, including Klaas Kersting, the former CEO and founder of online games leader Gameforge. Flaregames is committed to an environment free of office politics under the belief that in the games industry, it should be fun to come to work and rewarding to be a part of a great team. The company is venture-backed, having raised $23 Million to employ the best people in mobile games and ensure the company fulfills its destiny of becoming a major publisher reaching and entertaining the massive global audience of mobile gamers.
Total amount:93
1st
INERATECINERATEC develops innovative synthetic fuels and power-to-X plants aimed at replacing fossil fuels with carbon-neutral alternatives. The company focuses on creating sustainable energy solutions for transportation and everyday products, contributing to a post-fossil fuel economy.
2nd
DaedalusDaedalus is building the world’s most advanced factories for precision components. With $40M in funding from Khosla Ventures, Addition, NGP Capital and Y Combinator, and a team from OpenAI, Google, SpaceX and Blue Horizon, we’re building software-defined factories where we’re producing parts for companies in semiconductor, aerospace, medical, energy, defense and more.
3rd
LinearityLinearity is a software company whose products are designed to breathe new life into the design process and provide innovative ways of visualizing ideas. Known previously for the vector graphic design software Vectornator, Linearity’s product lineup includes vector and motion design tools like Linearity Curve and Linearity Move, tailored for both marketing professionals and enthusiasts. Linearity’s products are used to create millions of design assets every week.
Total amount:93

1st
AXOOMAXOOM's digital business platform streamlines connections between machinery, software, and processes, prioritizing user integration. The platform spans the production value chain, enhancing efficiency and collaboration.
2nd
INERATECINERATEC develops innovative synthetic fuels and power-to-X plants aimed at replacing fossil fuels with carbon-neutral alternatives. The company focuses on creating sustainable energy solutions for transportation and everyday products, contributing to a post-fossil fuel economy.
3rd
FaregamesFlaregames is a fast-growing mobile game publisher and developer that is focused on creating and bringing fun, high-quality, free-to-play games to smartphones and tablets. The company has a pipeline of games in development internally, and is working with some of the most talented mobile game developers from around the world to bring their games to mobile gamer. Flaregames publishes and builds games across a number of top genres including Tower Defense (and Offense), Real-Time Strategy, RPG, and world building games. The company has also recently signed publishing partnerships with Subatomic Studios, Superweapon, and FuzzyCube Software as part of its portfolio publishing initiative to bring AAA titles from world-class studios to market. Based in sunny Karlsruhe, Germany, flaregames is located just an hour from Frankfurt, and two hours from Paris by train. The company was founded in 2011 by a group of industry veterans, including Klaas Kersting, the former CEO and founder of online games leader Gameforge. Flaregames is committed to an environment free of office politics under the belief that in the games industry, it should be fun to come to work and rewarding to be a part of a great team. The company is venture-backed, having raised $23 Million to employ the best people in mobile games and ensure the company fulfills its destiny of becoming a major publisher reaching and entertaining the massive global audience of mobile gamers.
4th
DaedalusDaedalus is building the world’s most advanced factories for precision components. With $40M in funding from Khosla Ventures, Addition, NGP Capital and Y Combinator, and a team from OpenAI, Google, SpaceX and Blue Horizon, we’re building software-defined factories where we’re producing parts for companies in semiconductor, aerospace, medical, energy, defense and more.
Total amount:93

1st
KlangioWe are a start-up based in Karlsruhe that has set itself the goal of establishing artificial intelligence in the world of music, and thus enabling musicians worldwide to transcribe their favourite music pieces fully automatically. Artificial intelligence in music? That’s right! Because music doesn’t just move us humans. The AI registers the sounds and converts them fully automatically into sheet music. Played, Heard, Printed. What is the underlying magic? We use a deep learning method for audio processing. This means that we have taught our AI to process notes by using millions of examples from music. Therefore, our AI doesn’t just register sounds, but is able to understand the musical structure. Clever, isn’t it?
2nd
WorkwiseConnecting companies and job seekers effortlessly, our platform equips organizations with essential tools to find the perfect team members. Streamlining the recruitment process, we aim to facilitate meaningful connections at any stage of a company's growth.

3rd
InStaffThe InStaff & Jobs GmbH is an online marketplace where businesses can browse through a curated list of potential employees and book them directly online. Currently InStaff only offers hostesses & event staff in germany, but in the longterm InStaff will expand to other verticals as well as other countries. Book hostesses & event staff online: https://en.instaff.jobs
Total amount:93
National Rank
(Germany)
15th
newRegional Rank
(Western Europe)
71st
12
Global Rank
(WorldWide)
304th
31