StartupBlink

49 Top startups in Enschede for July 2026

We rank PHIX, SciSports and Lionix in Enschede along with 46 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Enschede startup ecosystem ranks #467 globally and #9 in The Netherlands.

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Best Startups in Enschede for 2026

1st
PHIX logo
PHIXSB Score: 355

PHIX is a leading packaging foundry that specializes in assembly and packaging services for the photonics industry. It develops advanced optoelectronic modules across key photonic integrated circuit (PIC) technology platforms, including indium phosphide, silicon photonics, silicon nitride, and planar lightwave circuits.

View Full Page
Website
www.phix.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$21.9M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
2nd
SciSports logo
SciSportsSB Score: 338

SciSports is the industry standard for football companies and is used to support any decision or action, every day, minute or second. SciSports provides actionable insights to improve football performance by enabling parties to get the most out of football data. It's one of the fastest growing sports analytics companies in the world and a leading provider of football data intelligence to over 100 clients. The European Union selected SciSports as one of the next European Unicorns and the HYPE Foundation elected the company as the most innovative football company in the world (2017).

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Website
www.scisports.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$4.5M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
3rd
Lionix logo
LionixSB Score: 338

They provide customized solutions for OEM’s and System Integrators, from design to fully assembled modules, by vertical integration and in scalable production volumes. They maintain their technology leadership secured by a strong IP position. LioniX International core competences are in Photonic Integrated Circuits (PIC), customized MEMS, and opto-fluidics.

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Website
lionix-international.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$3.8M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
4th
OneThird logo
OneThirdSB Score: 324

Blockchain, Food Loss, Food Waste, Food Tech, Supply Chain, Big Data, Ag Tech, Digitization, AI, Shelf Life Prediction, Quality Assessment, Fresh Produce, Dynamic Routing, UN SDG 12.3, Spectroscopy, Mobile App, and NIR Spectroscopy

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Website
onethird.io
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$8.4M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
5th
IamFluidics logo
IamFluidicsSB Score: 302

IamFluidics uses unique manufacturing procedures to create superior, long-lasting, and appealing goods based on high-quality microparticles. Using innovative and disruptive 'in-air microfluidics' production technology, the company produces monodisperse microbeads with regulated form, size, and composition.

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Website
www.iamfluidics.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$4M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
6th
Dealerdirect Global BV logo

Dealerdirect is a Dutch platform that simplifies the car-buying process. Users can easily browse and purchase vehicles online, eliminating the hassle of negotiating with dealers.

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Website
www.dealerdirect.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$8.7M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
7th
Hy2Care logo
Hy2CareSB Score: 298

Hy2Care BV is a business start-up of the University of Twente, the Netherlands. It is Hy2Care’s ambition to introduce into the market the first cure for Osteoarthritis, the injectable hydrogel. Osteoarthritis is the 4th leading cause of mobility associated disability and affects more than 100 million patients in the Western world, who are all in need for an effective treatment. It is the aim of Hy2Care to change the future for patients suffering from osteoarthritis.

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Website
www.hy2care.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$15.6M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
8th
PESCHECK logo
PESCHECKSB Score: 291

Globalization, a hybrid workforce and increasing demand from risk and compliance changed the future of employment rapidly. PESCHECK provides information and insights that make trust possible and ensure that each employee is reliably represented. By creating an actionable and robust picture of each employee. PESCHECK is the all-in-one software designed to accelerate your onboarding process with digital, fast and automated background checks. Creating a user-friendly and secure candidate experience and saves time. #automated background checks #background checks #backgroud screening #background check software #pre employment screening #in employment screening #freelancer screening #backgroud checks API #hrtech #regtech #KYE

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Website
www.pescheck.io
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$921.7K
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
9th
LipoCoat logo
LipoCoatSB Score: 284

LipoCoat is a biotech spin-off from the University of Twente. The company has developed a coating technology which improves the safety and comfort of medical devices without using antibiotics or toxic substances. The LipoCoat® coatings are developed for medical devices, such as contact lenses, catheters and implants. The coating is bio-inspired, hydrophilic, anti-fouling, multi-purpose and sustainable. In the past 3 years, LipoCoat has won 15 awards, competitions and grants.

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Website
www.lipocoat.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$4.3M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
10th
Axign logo
AxignSB Score: 282

Axign is a fabless chip supplier serving the worldwide audio markets in consumer and professional audio. Its first product is a breakthrough audio controller chip, that combines benchmark performance with a low bill of materials for audio system manufacturers. The chip is specially suited for active speaker systems in streaming audio devices.

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Website
axign.nl
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$13M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
11th
Datacake logo
DatacakeSB Score: 270

Datacake provides a multi-purpose, low-code IoT platform that users to easily create custom white-label IoT applications, requiring no programming skills. Developers can use the Datacake platform to implement Industrial IoT use cases such as condition monitoring, data logging, real-time dashboards, and data analytics.

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Website
datacake.co
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$691.5K
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)

Total amount:32

Most Funded Startups in Enschede for 2026

The top three most funded startups in Enschede have raised total funding of more than USD 79.7M. QuiX has 0.92% more funding than PHIX.
1st
PHIX logo
PHIXSB Score: 355

PHIX is a leading packaging foundry that specializes in assembly and packaging services for the photonics industry. It develops advanced optoelectronic modules across key photonic integrated circuit (PIC) technology platforms, including indium phosphide, silicon photonics, silicon nitride, and planar lightwave circuits.

View Full Page
Website
www.phix.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$21.9M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
2nd
Hy2Care logo
Hy2CareSB Score: 298

Hy2Care BV is a business start-up of the University of Twente, the Netherlands. It is Hy2Care’s ambition to introduce into the market the first cure for Osteoarthritis, the injectable hydrogel. Osteoarthritis is the 4th leading cause of mobility associated disability and affects more than 100 million patients in the Western world, who are all in need for an effective treatment. It is the aim of Hy2Care to change the future for patients suffering from osteoarthritis.

View Full Page
Website
www.hy2care.com
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$15.6M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
3rd
Axign logo
AxignSB Score: 282

Axign is a fabless chip supplier serving the worldwide audio markets in consumer and professional audio. Its first product is a breakthrough audio controller chip, that combines benchmark performance with a low bill of materials for audio system manufacturers. The chip is specially suited for active speaker systems in streaming audio devices.

View Full Page
Website
axign.nl
Employee range
1 – 10
Web Traffic (Monthly)
Funding amount
$13M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)

Total amount:32

Top Hiring Startups in Enschede by Employee Number

The top three hiring startups in Enschede have an median employee size that is between [51-100]
1st
PHIX logo
PHIXSB Score: 355

PHIX is a leading packaging foundry that specializes in assembly and packaging services for the photonics industry. It develops advanced optoelectronic modules across key photonic integrated circuit (PIC) technology platforms, including indium phosphide, silicon photonics, silicon nitride, and planar lightwave circuits.

View Full Page
Website
www.phix.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$21.9M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
2nd
Lionix logo
LionixSB Score: 338

They provide customized solutions for OEM’s and System Integrators, from design to fully assembled modules, by vertical integration and in scalable production volumes. They maintain their technology leadership secured by a strong IP position. LioniX International core competences are in Photonic Integrated Circuits (PIC), customized MEMS, and opto-fluidics.

View Full Page
Website
lionix-international.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$3.8M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
3rd
Dealerdirect Global BV logo

Dealerdirect is a Dutch platform that simplifies the car-buying process. Users can easily browse and purchase vehicles online, eliminating the hassle of negotiating with dealers.

View Full Page
Website
www.dealerdirect.com
Employee range
51 – 100
Web Traffic (Monthly)
Funding amount
$8.7M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)
4th
SciSports logo
SciSportsSB Score: 338

SciSports is the industry standard for football companies and is used to support any decision or action, every day, minute or second. SciSports provides actionable insights to improve football performance by enabling parties to get the most out of football data. It's one of the fastest growing sports analytics companies in the world and a leading provider of football data intelligence to over 100 clients. The European Union selected SciSports as one of the next European Unicorns and the HYPE Foundation elected the company as the most innovative football company in the world (2017).

View Full Page
Website
www.scisports.com
Employee range
11 – 50
Web Traffic (Monthly)
Funding amount
$4.5M
National Rank(The Netherlands)
Regional Rank(Western Europe)
Global Rank(Worldwide)

Total amount:49

Explore More Top Startups

Explore the Startup Ecosystem of Enschede

National Rank

(The Netherlands)

9th

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Regional Rank

(Western Europe)

141st

5

Global Rank

(WorldWide)

467th

13

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Top Cities for Startups in The Netherlands - Ranked by StartupBlink

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