Top Startup Exits in Chicago for 2025

In Chicago, we rank 23 startup exits based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Startup exits in Chicago are falling behind the performance of their global counterparts.

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Top Startup Exits in Chicago for 2025

SB Score:622

Tempus revolutionizes cancer care with precision medicine technology, enhancing treatment accuracy and outcomes.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Unranked

Order online from Chicago delivery and pickup restaurants. Whatever you're thinkin' Chicago, we got you.

Industry:
Foodtech
Subindustry:
Online Food Ordering

National Rank (United States)

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Unranked

Sphera is the leading provider of ESG performance and integrated risk management software, data and consulting services.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:23

Best Software & Data Startup Exits in Chicago for 2025

Chicago exits in the Software & Data industry are overperforming their global industry peers. The top three Software & Data exits in Chicago have raised more than USD 570M, an amount that is higher than the global industry average.
Unranked

Sphera is the leading provider of ESG performance and integrated risk management software, data and consulting services.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Unranked

DRIVIN is disrupting the used-car industry by providing dealers with a premier service that sources, acquires, delivers and markets the right used vehicles for their lot. Powered by data, our team has access to over 2M quality used-car VINs nationwide.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Unranked

Fast Radius, Inc. is a leading cloud manufacturing and digital supply chain company. The Cloud Manufacturing Platform™ from Fast Radius is a first-of-its-kind solution that integrates design, production, and fulfillment operations through a common digital infrastructure to make manufacturing easier, more accessible, and more sustainable. Founded in 2017, Fast Radius, Inc. is headquartered in Chicago with offices in Atlanta, Louisville, and Singapore and micro-factories in Chicago and at the UPS Worldport facility in Louisville, KY.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:11

Largest Startup Exits in Chicago by Funding

The top three largest startup exits in Chicago have raised total funding of more than USD 3M. Among the top three funded exits, the most popular industry, based on total funding, is Software & Data.
Unranked

Order online from Chicago delivery and pickup restaurants. Whatever you're thinkin' Chicago, we got you.

Industry:
Foodtech
Subindustry:
Online Food Ordering

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:622

Tempus revolutionizes cancer care with precision medicine technology, enhancing treatment accuracy and outcomes.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:23

Top Hiring Startup Exits in Chicago by Employee Size

The top three hiring startup exits in Chicago have an average employee size that is larger than to the global average. Among these, the Fintech industry features the startup exit with the largest workforce.
SB Score:622

Tempus revolutionizes cancer care with precision medicine technology, enhancing treatment accuracy and outcomes.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Unranked

VillageMD is a leading provider of healthcare for organizations moving toward a primary care-led, high-value clinical model.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Unranked

Home Chef is a provider of subscription-based meal kit delivery services to help people to save time while enjoying home cooking. It delivers pre-portioned ingredients and recipes to subscribers weekly, enabling users to prepare home-cooked meals in about 30 minutes.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:23

Explore the Startup Ecosystem of Chicago

National Rank

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6th

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Regional Rank

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6th

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Global Rank

(WorldWide)

15th

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

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Quantity Score
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Quality Score
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Business Score
1st
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1st
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710.966
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00.00
2nd
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2nd
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251.377
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3rd
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4th
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121.937
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00.00
4th
0
5th
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109.679
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00.00
00.00
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