Revology

Steel Therapeutics

Pear Deck

MCI World

Digital Diagnostics

Iowa City has 34 startups in our sample database.

Since 2025, Iowa City lost 59 spots in the Global Startup Ecosystem Index, having now positioned itself as 420th worldwide.

Explore Iowa City’s startup ecosystem which ranks 113th in The United States and 420th globally. Discover startups, unicorns, and exits in Iowa City. Dive into Healthtech, which is the best startup industry in Iowa City.

Startup Ecosystem of Iowa City | StartupBlink

Startups in Iowa City excel in Healthtech, Software & Data, and Ecommerce & and Retail.
    There are some notable success stories contributing to the city’s growing Healthtech
    industry. One of the most promising startups in Iowa City in 2025 is
    Pear Deck, MCI World, and Digital Diagnostics.

With a large variety of initiatives, Iowa City's startup ecosystem stands out from other cities in North America. Iowa City offers a number of funding opportunities for entrepreneurs and startups.
  Below is a list of Iowa City's most prominent support initiatives:

Within Iowa City there is an increased attraction for entrepreneurs
  to set up their startups in industries such as Healthtech, Software & Data, Ecommerce & Retail. These three industries represent about 41% of the startups
represented on the Startup Ecosystem Map of Iowa City. 

Iowa City is The United States' 113th best startup
  ecosystem and is ranked 128th in North America. With a population of 0.1M - 0.5M people,
   Iowa City is ranked 420th in the world. The city has some notable startup success stories
   including Pear Deck.

An inspiring ecosystem that is steadily due to its growing use of digital technologies, rapid urbanization and planned investments

WADAAG TECHNOLOGIES

Sostec

FGS Bill Tracker

Zaad

Wadaag Investment

A growing regional and global startup leader 

bitget.com

AscendEX

DeBank

Trip.com

Viki

A vibrant and strong startup hub attracting international recognition and investment

Cámara de Comercio de Bogotá

Founder Institute (FI) Bogota

RockStart Latam 

Calle 26 # 92-32

Carrera 7 #116-50

Carrera 19 # 100 - 45

Toastmasters Bogota

Picap

Autolab

Cubbo

Rappi

Addi

Bold

Carrera 12a #78-40

A leading regional startup hub owing its succes to the creative and innovative spirit of its people 

MiraKle Lab

VentureSquare

TIPS

Staion Neo

Sinsa

Gangnam Station

Seoul Business Agency

Contents First

Watcha

Lezhin Entertainment

OP.GG

SK Hynix

Bithumb

Fastfive Seocho 2

LocalStitch Yeongdeungpo

An innovative city with a global startup ecosystem

Nikkei

LIP. Yokohama (Life Innovation Platform Yokohama)

Project Ninja

THE BAYS

Nippon Life Nihonbashi Building

Metropolitan Plaza Building

Keio University, Hiyoshi Campus

RIKEN Yokohama Campus

YNU Yokohama National University

Locoguide

C Channel

note

PayPay

DM2C Studio

Timee

Regus - Tokyo, Kanda

OpenOffice - Tokyo, Nihonbashi Hakozaki (Open Office)

Regus - Tokyo, Ginza 3-Chome

One of the fastest growing ecosystems in Australia 

River City Labs

Buderim Meeting Rooms

The Boarding Office

INVEST Sunshine Coast

Delorean Project

Inform Ag

Coyo

NutWorks

Zitcha

Servatus

WOTSO

Inbox Workspace

A growing startup ecosystem owing to its workforce and industries.

Wings Accelerator

Centre for Energy and Power Electronics Research

The Hive (Pre-Accelerator) program for Women Entrepreneurs

Rose Innovation Hub

Queen’s University Rose Innovation Hub

Queen's University Smith School Of Business

Queen's Office of Partnerships and Innovation

Dunin-Deshpande Queen's Innovation Centre

Sparq Systems

FireRein

Green Graphite

IPG Photonics Canada

CMC Microsystems

Mosaic Manufacturing

Alon MedTech Ventures

Open Valley

Colab Square

Yokneam Municipality 

Startup Village Yokneam

Augmedics

ForSight Robotics

Rapid Medical

Chain Reaction

K2View

Pitch