4 Top startups in Southborough for February 2025

We rank Nirvana health, Biodirection and Upstart Power in Southborough along with 1 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Southborough is part of Boston Area startup ecosystem which ranks #5 globally and #4 in North America.

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Best Startups in Southborough for 2025

SB Score:357

BioDirection is revolutionizing medical care with handheld devices that screen and monitor mild brain injuries in real-time. Their innovative technology aims to improve patient outcomes and provide convenient, accurate diagnostics.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:319

Upstart Power is a private company specializing in solid oxide fuel cell systems that replace traditional internal combustion engine generators. Their innovative solutions enhance reliability, reduce costs, minimize noise, and lower emissions, making them ideal for residential use and critical communications infrastructure.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:218

Founded in 2008 by technology experts, Credorax is a pioneering fintech company that has become a Principal Member of Visa Europe and MasterCard. Specializing in e-commerce, Credorax offers Smart Acquiring to PSPs, ISOs, and online merchants, revolutionizing the payment processing industry.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Total amount:4

Top 2 Healthtech Startups in Southborough for 2025

The top three Healthtech startups in Southborough have raised more than USD 148M. Southborough is part of Boston Area startup ecosystem which ranks #2 globally for the Healthtech industry.
SB Score:357

BioDirection is revolutionizing medical care with handheld devices that screen and monitor mild brain injuries in real-time. Their innovative technology aims to improve patient outcomes and provide convenient, accurate diagnostics.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:2

Top 1 Ecommerce & Retail Startups in Southborough for 2025

Southborough is part of Boston Area startup ecosystem which ranks #11 globally for the Ecommerce & Retail industry.
SB Score:218

Founded in 2008 by technology experts, Credorax is a pioneering fintech company that has become a Principal Member of Visa Europe and MasterCard. Specializing in e-commerce, Credorax offers Smart Acquiring to PSPs, ISOs, and online merchants, revolutionizing the payment processing industry.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:1

Most Funded Startups in Southborough for 2025

The top three most funded startups in Southborough have raised total funding of more than USD 188M. Nirvana health has 1.77% more funding than Upstart Power.
SB Score:319

Upstart Power is a private company specializing in solid oxide fuel cell systems that replace traditional internal combustion engine generators. Their innovative solutions enhance reliability, reduce costs, minimize noise, and lower emissions, making them ideal for residential use and critical communications infrastructure.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:357

BioDirection is revolutionizing medical care with handheld devices that screen and monitor mild brain injuries in real-time. Their innovative technology aims to improve patient outcomes and provide convenient, accurate diagnostics.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:4

Top Hiring Startups in Southborough by Employee Number

The top three hiring startups in Southborough have an median employee size that is between [51-100]
SB Score:218

Founded in 2008 by technology experts, Credorax is a pioneering fintech company that has become a Principal Member of Visa Europe and MasterCard. Specializing in e-commerce, Credorax offers Smart Acquiring to PSPs, ISOs, and online merchants, revolutionizing the payment processing industry.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:357

BioDirection is revolutionizing medical care with handheld devices that screen and monitor mild brain injuries in real-time. Their innovative technology aims to improve patient outcomes and provide convenient, accurate diagnostics.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:319

Upstart Power is a private company specializing in solid oxide fuel cell systems that replace traditional internal combustion engine generators. Their innovative solutions enhance reliability, reduce costs, minimize noise, and lower emissions, making them ideal for residential use and critical communications infrastructure.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:4

Explore the Startup Ecosystem of Southborough

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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Quantity Score
Quality ScoreBusiness Score
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1st
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710.966
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2nd
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251.377
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3rd
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4th
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121.937
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4th
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5th
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109.679
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