48 Top startups in Manhattan for July 2025

We rank Allara, Constrafor and IYK in Manhattan along with 45 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Manhattan is part of New York startup ecosystem which ranks #2 globally and #2 in North America.

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Best Startups in Manhattan for 2025

SB Score:420

Allara provides comprehensive care for individuals with polycystic ovary syndrome (PCOS) through a dedicated medical provider and registered dietitian. They offer holistic support, including diagnostic testing, personalized prescriptions, video consultations, nutrition counseling, and lifestyle modifications to empower clients on their journey to better health.

Industry:
Foodtech
Subindustry:
Food and Beverage

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SB Score:411

Constrafor transforms construction management through its innovative SaaS fintech platform designed for general contractors and subcontractors. By streamlining back-office operations and financial transactions, it enhances productivity and reduces costs, enabling users to focus on what truly matters: building and delivering projects efficiently.

Industry:
Fintech
Subindustry:
Financial Services

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3rd

IYK
SB Score:409

IYK empowers brands, artists, and creators to seamlessly connect the physical and digital realms. By offering innovative tools and services, it enables the launch of engaging Web3 activations, transforming how audiences interact and experience content in a dynamic, interconnected landscape.

Industry:
Marketing & Sales
Subindustry:
Content Marketing

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SB Score:355

Porte + Hall offers a range of designer door mats for indoor and outdoor use, designed to seamlessly complement any architectural style. Their innovative products are durable, functional, and stylish, blending effortlessly with a variety of materials and finishes.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:320

Chatly revolutionizes brand-customer connections on WeChat with its cloud solutions. Chatly Commerce, Marketing, Sales, and Service streamline and enhance global WeChat strategies.

Industry:
Marketing & Sales
Subindustry:
Content Marketing

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SB Score:315

Ordaōs is a pioneering drug design company that combines human expertise with machine-driven technology to create tailored mini-proteins. By streamlining the drug discovery process, Ordaōs enables pharmaceutical and biotech companies worldwide to develop safer, more effective life-saving treatments in significantly less time than traditional methods.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:291

FlexPoint is an innovative payments platform designed specifically for the IT channel. It offers a seamless checkout experience with diverse payment options and provides white-label point-of-sale financing for high-value invoices, empowering businesses to enhance their transactions and customer satisfaction.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:289

Castellum.AI automates compliance screening for individuals and organizations, providing universal access to global compliance data. Our mission is to organize this data for seamless research, making it easy to stay on top of regulations.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:288

Chiyo is a maternal nutrition firm that specializes in meal delivery services tailored for fertility, pregnancy, and postpartum needs. By providing nutritious, chef-prepared meals, Chiyo supports women throughout their motherhood journey, ensuring they receive the essential nutrients for optimal health and well-being during this crucial time.

Industry:
Foodtech
Subindustry:
Food and Beverage

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SB Score:283

Dynamo Energy Hub is a worldwide network for energy innovators to collaborate and shape the future of the industry. Join industry leaders to drive global energy transformation.

Industry:
Energy & Environment
Subindustry:
Energy & Environment-Other

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OPEN is a fund management company supported by the New York Stock Exchange, offering a cutting-edge data, indexing, and sourcing platform. This innovative platform empowers the launch of index-based investment strategies focused on high-demand companies in private markets.

Industry:
Software & Data
Subindustry:
Data Analytics

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Total amount:48

Top 14 Software & Data Startups in Manhattan for 2025

The top three Software & Data startups in Manhattan have raised more than USD 19.4M. Manhattan is part of New York startup ecosystem which ranks #2 globally for the Software & Data industry.
SB Score:291

FlexPoint is an innovative payments platform designed specifically for the IT channel. It offers a seamless checkout experience with diverse payment options and provides white-label point-of-sale financing for high-value invoices, empowering businesses to enhance their transactions and customer satisfaction.

Industry:
Software & Data
Subindustry:
Enterprise Technology

City Rank (Manhattan)

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Regional Rank (North America)

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SB Score:289

Castellum.AI automates compliance screening for individuals and organizations, providing universal access to global compliance data. Our mission is to organize this data for seamless research, making it easy to stay on top of regulations.

Industry:
Software & Data
Subindustry:
Data Analytics

City Rank (Manhattan)

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Regional Rank (North America)

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OPEN is a fund management company supported by the New York Stock Exchange, offering a cutting-edge data, indexing, and sourcing platform. This innovative platform empowers the launch of index-based investment strategies focused on high-demand companies in private markets.

Industry:
Software & Data
Subindustry:
Data Analytics

City Rank (Manhattan)

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Total amount:14

Top 5 Fintech Startups in Manhattan for 2025

The top three Fintech startups in Manhattan have raised more than USD 64.7M. Manhattan is part of New York startup ecosystem which ranks #2 globally for the Fintech industry.
SB Score:411

Constrafor transforms construction management through its innovative SaaS fintech platform designed for general contractors and subcontractors. By streamlining back-office operations and financial transactions, it enhances productivity and reduces costs, enabling users to focus on what truly matters: building and delivering projects efficiently.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:259

Sandbar's activity monitoring software identifies suspicious activity and fraudulent behavior, streamlining the development, maintenance, and defense of anti-money laundering programs. By reducing effort and costs, Sandbar empowers organizations to enhance their compliance efforts and protect against financial crime effectively.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:243

Orb Labs is pioneering cross-chain messaging protocols and omnichain applications, enabling seamless communication and interaction across diverse blockchain networks. Designed for both developers and consumers, their innovative solutions simplify the creation and use of decentralized applications, fostering connectivity and collaboration in the blockchain ecosystem.

Industry:
Fintech
Subindustry:
Blockchain

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Total amount:5

Top 8 Ecommerce & Retail Startups in Manhattan for 2025

The top three Ecommerce & Retail startups in Manhattan have raised more than USD 1.56M. Manhattan is part of New York startup ecosystem which ranks #2 globally for the Ecommerce & Retail industry.
SB Score:355

Porte + Hall offers a range of designer door mats for indoor and outdoor use, designed to seamlessly complement any architectural style. Their innovative products are durable, functional, and stylish, blending effortlessly with a variety of materials and finishes.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

City Rank (Manhattan)

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Regional Rank (North America)

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SB Score:219

Cadence offers customizable, leakproof, and magnetic capsules designed to enhance routines and promote calm. Their innovative, modular containers are refillable and made from recycled ocean-bound plastic, providing an eco-friendly solution for organizing daily essentials while maintaining a sense of control and tranquility.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

City Rank (Manhattan)

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Total amount:8

Most Funded Startups in Manhattan for 2025

The top three most funded startups in Manhattan have raised total funding of more than USD 113M. Constrafor has 0.44% more funding than Allara.
SB Score:411

Constrafor transforms construction management through its innovative SaaS fintech platform designed for general contractors and subcontractors. By streamlining back-office operations and financial transactions, it enhances productivity and reduces costs, enabling users to focus on what truly matters: building and delivering projects efficiently.

Industry:
Fintech
Subindustry:
Financial Services

City Rank (Manhattan)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:420

Allara provides comprehensive care for individuals with polycystic ovary syndrome (PCOS) through a dedicated medical provider and registered dietitian. They offer holistic support, including diagnostic testing, personalized prescriptions, video consultations, nutrition counseling, and lifestyle modifications to empower clients on their journey to better health.

Industry:
Foodtech
Subindustry:
Food and Beverage

City Rank (Manhattan)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:315

Ordaōs is a pioneering drug design company that combines human expertise with machine-driven technology to create tailored mini-proteins. By streamlining the drug discovery process, Ordaōs enables pharmaceutical and biotech companies worldwide to develop safer, more effective life-saving treatments in significantly less time than traditional methods.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (Manhattan)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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Total amount:48

Top Hiring Startups in Manhattan by Employee Number

The top three hiring startups in Manhattan have an median employee size that is between [51-100]
SB Score:411

Constrafor transforms construction management through its innovative SaaS fintech platform designed for general contractors and subcontractors. By streamlining back-office operations and financial transactions, it enhances productivity and reduces costs, enabling users to focus on what truly matters: building and delivering projects efficiently.

Industry:
Fintech
Subindustry:
Financial Services

City Rank (Manhattan)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:320

Chatly revolutionizes brand-customer connections on WeChat with its cloud solutions. Chatly Commerce, Marketing, Sales, and Service streamline and enhance global WeChat strategies.

Industry:
Marketing & Sales
Subindustry:
Content Marketing

City Rank (Manhattan)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:420

Allara provides comprehensive care for individuals with polycystic ovary syndrome (PCOS) through a dedicated medical provider and registered dietitian. They offer holistic support, including diagnostic testing, personalized prescriptions, video consultations, nutrition counseling, and lifestyle modifications to empower clients on their journey to better health.

Industry:
Foodtech
Subindustry:
Food and Beverage

City Rank (Manhattan)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

4th

IYK
SB Score:409

IYK empowers brands, artists, and creators to seamlessly connect the physical and digital realms. By offering innovative tools and services, it enables the launch of engaging Web3 activations, transforming how audiences interact and experience content in a dynamic, interconnected landscape.

Industry:
Marketing & Sales
Subindustry:
Content Marketing

City Rank (Manhattan)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:48

Explore the Startup Ecosystem of Manhattan

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2025 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
1st
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1st
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852.643
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2nd
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315.515
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3rd
0
4th
0
139.115
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4th
0
6th
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1
128.476
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00.00
00.00
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