6 Top startups in Lake Saint Louis for February 2025

We rank NewLeaf Symbiotics, Heritage 1933 and Pulse Therapeutics in Lake Saint Louis along with 3 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Lake Saint Louis startup ecosystem ranks #null globally and #null in United States.

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Best Startups in Lake Saint Louis for 2025

NewLeaf Symbiotics is an agriculture technology firm focused on discovering and developing sustainable agricultural solutions based on bacteria and related microorganisms. The company's services are primarily focused on the study, development, and commercialization of symbiotic bacteria, which are helpful plant bacteria that help farmers combat plant disease and boost agricultural yields.

Industry:
Foodtech
Subindustry:
Agtech

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Heritage1933™ is a natural beauty company that challenges the narrow perception of beauty and aligns their mission seamlessly to celebrate natural beauty and improve the lives of women and children in need. With every product purchased, Heritage1933™ provides tools and products necessary to sustain hair care for women and children in local shelters.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Pulse Therapeutics is a growing medical technology company headquartered in St. Louis, Mo. The medical developer is advancing the fight against stroke, heart disease, and other conditions with its high-level treatment solutions, which utilize the latest biomedical technology and processes. Pulse’s signature offering, the MED System, was designed to harness magnet-based technology to rapidly dissolve blood clots faster than current modalities. This faster rate of delivery of FDA-approved clot-busting medication could dramatically reduce the number of lives lost each year to stroke, heart disease, and other diseases. This pioneering medical development company was founded by leading physicists Francis “Duke” Creighton and Rogers Ritter. Dr. Creighton, who also serves as Pulse’s chief technical officer, has 20-plus years of expertise in the medical technology industry, specializing in the stroke and cardiovascular sectors. He responsible for 30 patents and is a technology reviewer for the National Cancer Institute, National Science Foundation, and National Institutes of Health. The ground-breaking medical solutions of Pulse Therapeutics continues to attract investors and garner media coverage.

Industry:
Healthtech
Subindustry:
Biotechnology

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Formerly Known as Vasculox. Arch Oncology is an immuno-oncology company developing anti-CD47 antibodies for the treatment of solid and hematologic cancers. The company's functionally diverse antibodies represent a new class of checkpoint inhibitors that harness both the adaptive and innate immune responses.

Industry:
Healthtech
Subindustry:
Biotechnology

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TierPoint is a national provider of information technology and data center services, including colocation, cloud computing, and managed IT services, with corporate headquarters in St. Louis, MO. TierPoint was formed in 2010 through the strategic combination of some of the country's most respected and innovative data centers and IT solution providers whose origins date back as early as 1995.

Industry:
Hardware & IoT
Subindustry:
Hardware

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Boundless provides product support, training, and core development to meet your geospatial requirements. By providing the first open GIS ecosystem—a commercially-supported open-source platform and family of powerful products—Boundless is unlocking the full value of location-based data. They’re not an average group of software developers and geospatial geeks. In fact, they’re the world’s foremost leading authority on open source GIS and location-based data. Over the past 14 years, Boundless has set the standard in open source geospatial expertise. Their team is active in the open source geospatial (FOSS4G) community, gathering and sharing their deep understanding of GIS theories and concepts. They’re now expanding this expertise by introducing the first open GIS ecosystem, unlocking the value of location-based data for all.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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Total amount:6

Top 2 Healthtech Startups in Lake Saint Louis for 2025

Lake Saint Louis startup ecosystem ranks among the top 10 locations in the world for startups in Healthtech, holding the 1st position.

Pulse Therapeutics is a growing medical technology company headquartered in St. Louis, Mo. The medical developer is advancing the fight against stroke, heart disease, and other conditions with its high-level treatment solutions, which utilize the latest biomedical technology and processes. Pulse’s signature offering, the MED System, was designed to harness magnet-based technology to rapidly dissolve blood clots faster than current modalities. This faster rate of delivery of FDA-approved clot-busting medication could dramatically reduce the number of lives lost each year to stroke, heart disease, and other diseases. This pioneering medical development company was founded by leading physicists Francis “Duke” Creighton and Rogers Ritter. Dr. Creighton, who also serves as Pulse’s chief technical officer, has 20-plus years of expertise in the medical technology industry, specializing in the stroke and cardiovascular sectors. He responsible for 30 patents and is a technology reviewer for the National Cancer Institute, National Science Foundation, and National Institutes of Health. The ground-breaking medical solutions of Pulse Therapeutics continues to attract investors and garner media coverage.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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Unranked

Formerly Known as Vasculox. Arch Oncology is an immuno-oncology company developing anti-CD47 antibodies for the treatment of solid and hematologic cancers. The company's functionally diverse antibodies represent a new class of checkpoint inhibitors that harness both the adaptive and innate immune responses.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:2

Top 1 Ecommerce & Retail Startups in Lake Saint Louis for 2025

Lake Saint Louis startup ecosystem ranks among the top 10 locations in the world for startups in Ecommerce & Retail, holding the 2nd position.
Unranked

Heritage1933™ is a natural beauty company that challenges the narrow perception of beauty and aligns their mission seamlessly to celebrate natural beauty and improve the lives of women and children in need. With every product purchased, Heritage1933™ provides tools and products necessary to sustain hair care for women and children in local shelters.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:1

Top 1 Software & Data Startups in Lake Saint Louis for 2025

Lake Saint Louis startup ecosystem ranks among the top 10 locations in the world for startups in Software & Data, holding the 3rd position.

Boundless provides product support, training, and core development to meet your geospatial requirements. By providing the first open GIS ecosystem—a commercially-supported open-source platform and family of powerful products—Boundless is unlocking the full value of location-based data. They’re not an average group of software developers and geospatial geeks. In fact, they’re the world’s foremost leading authority on open source GIS and location-based data. Over the past 14 years, Boundless has set the standard in open source geospatial expertise. Their team is active in the open source geospatial (FOSS4G) community, gathering and sharing their deep understanding of GIS theories and concepts. They’re now expanding this expertise by introducing the first open GIS ecosystem, unlocking the value of location-based data for all.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:1

Most Funded Startups in Lake Saint Louis for 2025

The top three most funded startups in Lake Saint Louis have raised total funding of more than USD 0. Arch Oncology has NaN% more funding than NewLeaf Symbiotics.

NewLeaf Symbiotics is an agriculture technology firm focused on discovering and developing sustainable agricultural solutions based on bacteria and related microorganisms. The company's services are primarily focused on the study, development, and commercialization of symbiotic bacteria, which are helpful plant bacteria that help farmers combat plant disease and boost agricultural yields.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
Unranked

Heritage1933™ is a natural beauty company that challenges the narrow perception of beauty and aligns their mission seamlessly to celebrate natural beauty and improve the lives of women and children in need. With every product purchased, Heritage1933™ provides tools and products necessary to sustain hair care for women and children in local shelters.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Pulse Therapeutics is a growing medical technology company headquartered in St. Louis, Mo. The medical developer is advancing the fight against stroke, heart disease, and other conditions with its high-level treatment solutions, which utilize the latest biomedical technology and processes. Pulse’s signature offering, the MED System, was designed to harness magnet-based technology to rapidly dissolve blood clots faster than current modalities. This faster rate of delivery of FDA-approved clot-busting medication could dramatically reduce the number of lives lost each year to stroke, heart disease, and other diseases. This pioneering medical development company was founded by leading physicists Francis “Duke” Creighton and Rogers Ritter. Dr. Creighton, who also serves as Pulse’s chief technical officer, has 20-plus years of expertise in the medical technology industry, specializing in the stroke and cardiovascular sectors. He responsible for 30 patents and is a technology reviewer for the National Cancer Institute, National Science Foundation, and National Institutes of Health. The ground-breaking medical solutions of Pulse Therapeutics continues to attract investors and garner media coverage.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:6

Top Hiring Startups in Lake Saint Louis by Employee Number

The top three hiring startups in Lake Saint Louis have an median employee size that is between [251-500]
Unranked

TierPoint is a national provider of information technology and data center services, including colocation, cloud computing, and managed IT services, with corporate headquarters in St. Louis, MO. TierPoint was formed in 2010 through the strategic combination of some of the country's most respected and innovative data centers and IT solution providers whose origins date back as early as 1995.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Pulse Therapeutics is a growing medical technology company headquartered in St. Louis, Mo. The medical developer is advancing the fight against stroke, heart disease, and other conditions with its high-level treatment solutions, which utilize the latest biomedical technology and processes. Pulse’s signature offering, the MED System, was designed to harness magnet-based technology to rapidly dissolve blood clots faster than current modalities. This faster rate of delivery of FDA-approved clot-busting medication could dramatically reduce the number of lives lost each year to stroke, heart disease, and other diseases. This pioneering medical development company was founded by leading physicists Francis “Duke” Creighton and Rogers Ritter. Dr. Creighton, who also serves as Pulse’s chief technical officer, has 20-plus years of expertise in the medical technology industry, specializing in the stroke and cardiovascular sectors. He responsible for 30 patents and is a technology reviewer for the National Cancer Institute, National Science Foundation, and National Institutes of Health. The ground-breaking medical solutions of Pulse Therapeutics continues to attract investors and garner media coverage.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
Unranked

Formerly Known as Vasculox. Arch Oncology is an immuno-oncology company developing anti-CD47 antibodies for the treatment of solid and hematologic cancers. The company's functionally diverse antibodies represent a new class of checkpoint inhibitors that harness both the adaptive and innate immune responses.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

NewLeaf Symbiotics is an agriculture technology firm focused on discovering and developing sustainable agricultural solutions based on bacteria and related microorganisms. The company's services are primarily focused on the study, development, and commercialization of symbiotic bacteria, which are helpful plant bacteria that help farmers combat plant disease and boost agricultural yields.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:6

Explore the Startup Ecosystem of Lake Saint Louis

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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Quantity Score
Quality ScoreBusiness Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
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