22 Top startups in Frankfort for April 2025

We rank Payhoa, My Racehorse and Purchaser in Frankfort along with 19 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Frankfort startup ecosystem ranks #1018 globally and #244 in United States.

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Best Startups in Frankfort for 2025

SB Score:460

This innovative software simplifies daily tasks for residents and property managers, enhancing communication and streamlining operations. By centralizing essential functions, it fosters a more efficient living environment, making life easier for everyone involved in the community.

Industry:
Software & Data
Subindustry:
SaaS

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SB Score:423

My Racehorse is an innovative online platform that enables users to legally purchase shares in racehorses. With features like easy searching and comparison, instant online buying, regular updates on horse performance, and access to exclusive ownership events, it offers a unique experience for aspiring racehorse owners.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

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SB Score:299

Purchaser enhances the indirect procurement process with autonomous purchasing agents that operate continuously, 24/7. These digital agents seamlessly connect internal and external data to identify optimal prices, lead times, and other essential information on industrial products, streamlining procurement and improving efficiency.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:285

Nymbl Systems provides innovative healthcare management software designed to enhance the medical experience. By streamlining documentation processes, it enables healthcare professionals to dedicate more time to patient care, ultimately improving outcomes and fostering stronger patient-provider relationships.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:284

Commonwealth offers a unique investment platform that enables users to invest in athletes, specifically golfers and racehorses, allowing them to engage with the sports world in a new and exciting way while potentially benefiting from the athletes' successes.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

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SB Score:255

SalesRiver is an all-in-one sales platform designed for distributed teams, enabling seamless collaboration and streamlined communication. It empowers users to manage their sales processes efficiently, enhancing productivity and driving results in a dynamic work environment.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:254

Nexosome Oncology specializes in using exosome-based diagnostics for cancer detection and monitoring. Their innovative approach offers advanced solutions in the field of oncology.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Regional Rank (North America)

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SB Score:236

This startup revolutionizes cataract surgery outcomes by developing advanced technologies that enhance visual clarity post-operation. By addressing the limitations of current surgical methods and intraocular lens designs, it aims to significantly improve the percentage of patients who can see clearly without glasses after their procedure.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:221

PlanStreet develops case management software for nonprofits, healthcare, and human services. Their goal is to empower organizations by automating processes and providing easy access to information, helping staff operate at their best.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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SB Score:218

Thynk Health offers an innovative platform for managing cancer screenings and incidental findings. By streamlining the process, it empowers healthcare providers to enhance patient care, ensuring timely follow-ups and improved outcomes in cancer detection and management.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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SB Score:216

Churnlify provides cutting-edge, machine learning-driven sales analytics tailored for small and medium-sized enterprises (SMEs) in the German-speaking DACH region. By leveraging advanced insights, it empowers businesses to enhance sales strategies and boost performance effectively.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Regional Rank (North America)

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Total amount:22

Top 8 Software & Data Startups in Frankfort for 2025

The top three Software & Data startups in Frankfort have raised more than USD 39M. Frankfort startup ecosystem ranks among the top 10 locations in the world for startups in Software & Data, holding the falseth position.
SB Score:460

This innovative software simplifies daily tasks for residents and property managers, enhancing communication and streamlining operations. By centralizing essential functions, it fosters a more efficient living environment, making life easier for everyone involved in the community.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:285

Nymbl Systems provides innovative healthcare management software designed to enhance the medical experience. By streamlining documentation processes, it enables healthcare professionals to dedicate more time to patient care, ultimately improving outcomes and fostering stronger patient-provider relationships.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:284

Commonwealth offers a unique investment platform that enables users to invest in athletes, specifically golfers and racehorses, allowing them to engage with the sports world in a new and exciting way while potentially benefiting from the athletes' successes.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:8

Top 4 Healthtech Startups in Frankfort for 2025

The top three Healthtech startups in Frankfort have raised more than USD 4.32M. Frankfort startup ecosystem ranks among the top 10 locations in the world for startups in Healthtech, holding the falseth position.
SB Score:254

Nexosome Oncology specializes in using exosome-based diagnostics for cancer detection and monitoring. Their innovative approach offers advanced solutions in the field of oncology.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:236

This startup revolutionizes cataract surgery outcomes by developing advanced technologies that enhance visual clarity post-operation. By addressing the limitations of current surgical methods and intraocular lens designs, it aims to significantly improve the percentage of patients who can see clearly without glasses after their procedure.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:218

Thynk Health offers an innovative platform for managing cancer screenings and incidental findings. By streamlining the process, it empowers healthcare providers to enhance patient care, ensuring timely follow-ups and improved outcomes in cancer detection and management.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:4

Top 2 Ecommerce & Retail Startups in Frankfort for 2025

The top three Ecommerce & Retail startups in Frankfort have raised more than USD 7.11M. Frankfort startup ecosystem ranks among the top 10 locations in the world for startups in Ecommerce & Retail, holding the falseth position.
SB Score:423

My Racehorse is an innovative online platform that enables users to legally purchase shares in racehorses. With features like easy searching and comparison, instant online buying, regular updates on horse performance, and access to exclusive ownership events, it offers a unique experience for aspiring racehorse owners.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:216

Discover a curated selection of premium coffee blends and accessories at our online shop. Indulge in the perfect brew with our high-quality products, from beans to brewing equipment. Elevate your coffee experience with us.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:2

Most Funded Startups in Frankfort for 2025

The top three most funded startups in Frankfort have raised total funding of more than USD 42.1M. Payhoa has 2.67% more funding than Nymbl Systems.
SB Score:460

This innovative software simplifies daily tasks for residents and property managers, enhancing communication and streamlining operations. By centralizing essential functions, it fosters a more efficient living environment, making life easier for everyone involved in the community.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:285

Nymbl Systems provides innovative healthcare management software designed to enhance the medical experience. By streamlining documentation processes, it enables healthcare professionals to dedicate more time to patient care, ultimately improving outcomes and fostering stronger patient-provider relationships.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:423

My Racehorse is an innovative online platform that enables users to legally purchase shares in racehorses. With features like easy searching and comparison, instant online buying, regular updates on horse performance, and access to exclusive ownership events, it offers a unique experience for aspiring racehorse owners.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:22

Top Hiring Startups in Frankfort by Employee Number

The top three hiring startups in Frankfort have an median employee size that is between [51-100]
SB Score:285

Nymbl Systems provides innovative healthcare management software designed to enhance the medical experience. By streamlining documentation processes, it enables healthcare professionals to dedicate more time to patient care, ultimately improving outcomes and fostering stronger patient-provider relationships.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:236

This startup revolutionizes cataract surgery outcomes by developing advanced technologies that enhance visual clarity post-operation. By addressing the limitations of current surgical methods and intraocular lens designs, it aims to significantly improve the percentage of patients who can see clearly without glasses after their procedure.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:221

PlanStreet develops case management software for nonprofits, healthcare, and human services. Their goal is to empower organizations by automating processes and providing easy access to information, helping staff operate at their best.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:460

This innovative software simplifies daily tasks for residents and property managers, enhancing communication and streamlining operations. By centralizing essential functions, it fosters a more efficient living environment, making life easier for everyone involved in the community.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:22

Explore the Startup Ecosystem of Frankfort

National Rank

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Regional Rank

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290th

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Global Rank

(WorldWide)

1018th

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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121.937
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4th
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109.679
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