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The World Health Organization (WHO) had proposed the cardiovascular polypill more than a decade ago as a ‘best buy’ intervention for secondary prevention, and a simple, cost-effective strategy to reduce the evidence implementation gap and as an instrument to improve the prescription, accessibility, adherence and cost of secondary CVD prevention.The concept of a polypill, composed of a combination of medications that are known to effectively treat CVD, has been proposed as a simple, cost effective and innovative public health strategy to combat the CVD epidemic on a global scale. Several studies have shown the polypill to be well tolerated and superior in terms of adherence to standard of care.Polypills include guideline-recommended treatments for secondary prevention, such as BP-lowering, cholesterol-lowering and antiplatelet drugs. Polypill strategies have been shown to be effective.
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