We’ve put together a list of the top tech and startup podcasts in 2025—shows we consistently turn to for sharp thinking, fresh perspectives, and practical advice. These are the ones we genuinely enjoy listening to, and we believe they offer real value to anyone building or backing the next generation of companies.
If you host a podcast that helps startups grow and innovate, feel free to contact us—we’re always looking to expand this list with shows worth listening to.
Top Startup & Tech Podcasts of 2025
20VC (The Twenty Minute VC)
Host: Harry Stebbings
Arguably one of the most influential voices in VC, Harry Stebbings continues to deliver fast-paced, high-quality interviews with top investors, operators, and founders. The 2025 season sees deeper dives into AI investing, global LP trends, and emerging fund managers.
a16z Podcast
Host: Andreessen Horowitz team
The a16z Podcast is a staple for anyone wanting to explore trends in technology, business models, and startup strategy. This year, its AI-focused mini-series and deep dives into biotech, defense tech, and decentralization stand out.
How I Built This
Host: Guy Raz
Hosted by Guy Raz, How I Built This features in-depth conversations with some of the world’s most well-known entrepreneurs. Each episode explores the highs and lows behind iconic brands, offering a candid look at the personal doubts, failures, and breakthroughs that shaped their journeys. It’s a compelling masterclass in innovation, resilience, and leadership.
This Week in Startups
Host: Jason Calacanis
Hosted by Jason Calacanis, This Week in Startups dives into the latest in startups, technology, markets, and media. The show features sharp commentary on current trends, along with in-depth interviews with some of the world’s top founders, investors, and industry leaders. It’s a must-listen for anyone following the pulse of innovation.
Acquired
Hosts: Ben Gilbert and David Rosenthal
Every great company has a story. Acquired unpacks the strategies behind the rise (and occasional fall) of the world’s most iconic companies, from Nvidia to OpenAI. Each episode is a deep dive, blending meticulous research with compelling storytelling. With multi-hour formats, it’s a goldmine for strategic thinkers looking to learn from the best.
The Knowledge Project
Host: Shane Parrish
The Knowledge Project explores the art of decision-making, mental models, and leadership. Often featuring founders and tech leaders, the podcast dives into the psychology and strategic thinking that underpin high performance and long-term success.
The Tim Ferriss Show
Host: Tim Ferriss
Tim Ferriss blends performance science, entrepreneurship, and deep introspection in long-form conversations with world-class achievers. His 2025 content highlights peak founder routines, mental resilience frameworks, and unorthodox paths to innovation. This year’s standout episodes include interviews with biotech pioneers, creators scaling media empires, and angel investors rewriting the playbook. A must-listen for those looking to enhance both business and life performance.
Business Wars
Host: David Brown
Narrated like a gripping audio drama, Business Wars dissects legendary company rivalries. The 2025 season dives into the battles shaping the next economy: OpenAI vs. Google DeepMind, Tesla vs. BYD, and Amazon vs. Shopify 2.0. With rich storytelling, each arc reveals the psychology of disruption and the strategic missteps that define market winners and losers. Ideal for founders navigating competitive landscapes and product moats.
Innovation Rockstars
Host: Dr. Christian Mühlroth
Produced by ITONICS, this podcast sits at the intersection of corporate foresight, strategic innovation, and future trends. Dr. Mühlroth interviews thought leaders from Fortune 500 companies, research institutes, and startups. The 2025 season covers AI in R&D, venture clienting models, and how corporations are using scenario planning to build resilient innovation portfolios. Especially valuable for innovation managers and strategy leads.
Talk Innovation: Unlocking Technology
Host: Johannes Schaaf
Brought to you by the European Patent Office, this podcast zooms in on breakthrough technologies and the inventors behind them. In 2025, the show explores frontier topics like quantum materials, green hydrogen, and the ethics of tech patenting in AI. It’s a compelling blend of science, entrepreneurship, and policy — ideal for deep-tech founders and corporate R&D leaders.
Technovation
Host: Peter High
Peter High has spent over a decade advising CIOs and innovation executives — and his podcast reflects that experience. In 2025, Technovation focuses on the intersection of IT leadership and business strategy, covering topics like AI as a co-pilot for decision-making, the role of the Chief Innovation Officer, and smart infrastructure. With frequent guests from Fortune 100 companies, it’s tailored for enterprise innovators navigating digital transformation.
Innovation Answered
Host: The Innovation Leader Team
This podcast distills real-world lessons from corporate innovation teams. The 2025 season covers how global companies are reinventing internal incubation, measuring innovation ROI, and bridging the gap between product and strategy. With its case-study-driven format, it’s particularly useful for those leading innovation in complex or regulated industries.
Culture of Innovation
Host: Nancy Ridge
Nancy Ridge brings a seasoned perspective on how organizations foster ecosystems of innovation. Her 2025 interviews explore how culture, diversity, and strategic partnerships drive exponential value. From government innovation labs to telecom consortiums, each episode is a thoughtful exploration of collaborative growth — perfect for ecosystem builders, intrapreneurs, and transformation consultants.
Who Should Tune In?
- Startup founders gain insights from industry leaders and real-world case studies.
- Investors and VCs discover new trends, emerging ecosystems, and unfiltered founder perspectives.
- Policy makers and ecosystem developers hear directly from the voices shaping innovation policy.
- Corporate innovation teams stay informed on disruption and strategic partnerships.
- Students and aspiring entrepreneurs can learn, be inspired, and start building with the right knowledge.
Whether you’re scaling a startup or exploring the space for the first time, these shows offer immense value, fresh perspectives, and inspiration from the front lines of innovation.
If you have a podcast that you believe should be listed here, please contact us.