PlenSat is a preclinical stage biomedical device venture pursuing its patented technology for the treatment of obesity. PlenSat ‘Digestible Balloons™” are a unique approach which may achieve the benefits of Bariatric therapy to treat obesity without invasive techniques such as surgery, laparoscopy or endoscopy. Digestible Balloons promise the simplicity of pharmaceutical dosage with the weight loss profile of Bariatric therapy.
PlenSat’s technology involves the production of ingestible ‘pills’ that are self-inflating in the acidic environment within the stomach. The expanded capsule, a “Digestible Balloon”, is sized such that once inflated it will not pass beyond the stomach. Preclinical pilot studies in dogs have shown that the capsules do inflate to the appropriate size to remain in the stomach for an extended time. The Digestible Balloon is ultimately broken down in the stomach over time and residual material is digested in the intestine and passed.